We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Public research university in Kansas City, Missouri. UMKC is part of the University of Missouri System and one of only two member universities with a medical school.
Core offers biobanking services and diverse inventory of biospecimens in the field of Oncology. Offers prospective protocol specific banking tailored to your research needs, including patient eligibility, screening, consenting, biospecimen procurement, handling, and processing, clinical data annotation, short and long-term sample storage, and shipping.
Project aimed at making neuroimaging data sets of brain freely available to scientific community. By compiling and freely distributing neuroimaging data sets, future discoveries in basic and clinical neuroscience are facilitated.
A coeducational public research university located in Oklahoma, USA. The institution confers undergraduate and graduate degrees in fields such as law, medicine, aviation, energy management, history of science, and Native American studies.
Core provides mass-spectrometry solutions for small-molecule research. Supports experimental design, ensuring proper handling, appropriate controls, and adequate statistical power, and then executes analyses on Thermo Orbitrap IQ-X and Agilent 6495D LC/MS systems and an Agilent 5977C GC/MS system. Using validated methods annotated against a library of 1,000+ compounds, we maximize metabolite and small-molecule coverage. We also offer untargeted profiling for biomarker and novel metabolite and lipid discovery, as well as stable-isotope tracing for measuring substrate utilization. Results are delivered with custom informatics and statistical interpretation for faster, more approachable insights.
V-Cell is a remote user modeling and simulation environment utilizing Java''s Remote Method Invocation (RMI). The biologically oriented user interface allows experimentalists to create models, define cellular geometry, specify simulations and analyze the simulation results. The results are run and stored on a remote server and can be reviewed in the software and/or exported in a variety of popular formats. The design of the biological to mathematical mapping allows for separate use of biological and math components, and includes automatic mathematical simplification using pseudo-steady approximations and mass conservation relationships. This allows for direct specification of mathematical problems, performing simulations and analysis on those systems. The stand alone mathematics user interface is also a powerful tool for modeling reaction-diffusion systems. A transparent general purpose solver is used to translate the initial biological description into a set of concise mathematical problems. The solver is transparent to the average user, but is accessible to the theorist as the Math Editor component. The software is composed of three main components: 1. The modeling framework represents the physiological models of the Virtual Cell and allows for persistence and database support. 2. The mathematics framework transparently solves an important class of mathematical problems encountered in the cellular modeling. 3. The WWW accessible graphical user interface provides access to the technology mentioned above. The user interface has been developed using Java 2 Applets.
Public university in the Brazilian state of São Paulo. It is the largest Brazilian public university.
Core Facility at the Icahn Genomics Institute (IGI) offers custom-made lipid nanoparticles and RNA technology to develop new therapeutics and nanomedicines.
CellCircuits is an open-access database of molecular network models. Its goal is to bridges the gap between databases of individual pair-wise molecular interactions and databases of validated pathways. It contains functional network hypotheses produced by algorithms that screen molecular interaction networks based on their correspondence with expression or phenotypic data, their internal structure, or their conservation across species. The database is searchable using protein/gene names and Gene Ontology terms. Models are available either as images or in machine-readable formats. Overall, this resource serves as a clearinghouse in which theorists may distribute or revise models in need of validation and experimentalists may search for models or specific hypotheses relevant to their interests. Funding provided by the National Science Foundation (NSF 0425926).
A public research university in Sydney, Australia that offers a wide range of degree programs at the undergraduate and graduate level.
Core provides data-related support to cancer researchers by offering services like study design consultation, data management, programming, and access to patient data. Its purpose is to help researchers develop and execute studies, manage data, analyze results, and ultimately accelerate cancer research by making large, complex datasets more accessible and usable. CDS team uses evidence-based standards and effective quality assurance procedures from project design to study end. All CDS study staff are HIPAA-compliant and certified in Human Subjects and Good Clinic Practice training.
HepSEQ is the International Repository for Hepatitis B Virus Strain Data. It is web-accessible, quality-based, molecular, clinical and epidemiological database for hepatitis B infection and provides a tool for the research community or for those involved in hepatitis B case management. This database currently has 1012 patient records and 1253 viral sequences. The quality of all submitted sequences is checked. The tools provided include: SeqMatch: search the database for matching sequences Genotyper: genotype HBV strains (based on HBV surface antigen genes) Gene Mutation: display the sequences that contain mutations in HBV coding regions Mutation Annotator: annotate sequences for mutation known to be associated with anti-viral resistance This web database development is funded by the UK Department of Health is curated and is hosted by the Health Protection Agency.
Public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 28,2022. InterPare is a database server for protein interaction interface information. It contains large-scale interface data of proteins whose 3D-structures are known. Protein interface information is derived from three different methods. InterPare introduces a large-scale protein domain interaction interface database called InterPare. InterPare uses three methods: 1) the Euclidean distance method for checking the distance among subunits in multidomain proteins, 2) Accessible Surface Area (ASA) for detecting the buried region of a protein that is detached from a solvent when forming multimers or complexes, 3) the Voronoi diagram, a computational geometry method, that uses a mathematical definition of interface regions. InterPare includes tools with different display modes for viewing protein interior, surface, and interaction interfaces.
OPD is a public database for storing and disseminating mass spectrometry based proteomics data. It covers Escherichia coli, Homo sapiens, Saccharomyces cerevisiae, Mycobacterium smegmatis, and Mus musculus. The database currently contains roughly 3,000,000 spectra representing experiments from these 5 different organisms. The mirror url is provided below as the OPD website is no longer functional (http://bioinformatics.icmb.utexas.edu/OPD/).
Private, coeducational, liberal arts college in Poughkeepsie, New York.
Medical hospital-based research institute in Montreal, Quebec, Canada.
A sister database to ProSite, is constituted of manually created rules that increase the discriminatory power of PROSITE motifs (generally profiles) by providing additional information about functionally and/or structurally critical amino acids and can automatically generate annotation based on PROSITE motifs in the UniProtKB/Swiss-Prot format. Each ProRule is defined in the UniRule format. In addition to these rules corresponding to a unique PROSITE motif, there are also rules triggered by a specific combination of PROSITE motifs called metamotifs. Metamotifs allow the definition of arrangements of domains separated by spacers of variable size, as well as the anchoring to the N- and/or C-termini and the exclusion of a PROSITE motif. ProRule uses the UniRule format that is common to all types of rules created to annotate UniProtKB/Swiss-Prot, including the HAMAP family rules. Each rule contains information used to provide template based annotation associated with the domain or family detected by the PROSITE motif. ProRule is used to create UniProtKB/Swiss-Prot lines with basic and complex annotation derived from the presence of the domain and of biologically critical amino acids: domain name and boundaries, EC number, function, keywords, associated PROSITE patterns, PTMs, active sites, disulfide bonds, etc.). ProRule contains notably the position of structurally and/or functionally critical amino acid(s), as well as the condition(s) they must fulfil to play their biological role(s). Part of these supplementary data are used by ScanProsite that not only provides the protein sequence matched by a profile, but also information about the relevance of biologically meaningful residues, like active sites, binding sites, post-translational modification sites or disulfide bonds, to help function determination
Private research university in Seoul, South Korea. Particularly respected in studies of medicine and business administration.
Software package for the R Environment. Used for estimating multidimensional item response theory parameters for exploratory and confirmatory models by using maximum-likelihood meth- ods.