Curator Dashboard

Software package to visualize and analyze structural and functional characteristics of cerebral and cerebellar cortex in humans, nonhuman primates, and rodents. Runs on Apple (Mac OSX), Linux, and Microsoft Windows operating systems.

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• SciCrunch
• 17 years ago - by Anonymous

Provides biorepository resources, services and expertise in support of oncology research.Facilitates translational cancer research with standard operating procedures for patient consenting; protection of patient personal and clinical data; specimen procurement and processing; quality control of specimens; secured specimen storage, retrieval, and distribution; and provision of relevant de-identified clinical data. BSSR services include: biospecimen collection, annotation, processing, storage and distribution (including tissue, blood, and other fluids); plasma, serum, and peripheral blood mononuclear cell processing and cryopreservation; rapid acquisition of surgical tissue and fresh biopsies; participant screening and enrollment for biospecimen collection studies;formalin-fixed, paraffin embedded and frozen tissue retrieval, processing, sectioning, histological staining, and digital whole slide scanning; tissue microarrays production; support for non-therapeutic trials; consultation on project design, data analysis and interpretation. Offers access tobiobank of diverse tissue types, including clinically annotated neoplastic and non-neoplastic samples from diverse anatomical sites, and provides banked specimen as well as fresh specimen procurement at institution wide level.Through BSSR, investigators have access to specimens collected fromUniversity of Miami Hospital, Sylvester Comprehensive Cancer Center, Bascom Palmer Eye Institute, Jackson Memorial Hospital, as well as to specimens collected in more broadly based multi-site studies.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides education and training on the use of noninvasive brain stimulation for both clinical practice and research. Uses techniques like TMS and tDCS for diagnosing, treating, and researching neuropsychiatric conditions, aiding neurorehabilitation after brain injuries, and educating professionals, focusing on disorders like depression, schizophrenia, epilepsy, chronic pain, and stroke recovery to improve brain function and quality of life

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• SciCrunch
• 13 years ago - by Anonymous

Provides genetically modified animal models for our collaborators. For preexisting models provides rederivation or reconstitution for purpose of importing animals into Vivarium barrier. In the absence of preexisting models core works closely with partnering labs to generate their ideal mutation de novo, often using CRISPR technology. Usually beginning with a brief consultation, this process involves discussing factors such as ideal background strain, molecular methods for optimizing the intended genetic change, mutation induction strategies, screening approaches and eventual QC of the new mutant line with the overall goal of giving our collaborators a fully informed, realistic picture of their projects timeframe, pitfalls and workflow. Core provides mouse sperm and embryo cryopreservation services for purpose of archiving and distributing valuable lines. Institute is an AAALAC-accredited facility. All procedures are conducted according to the NIH Guide for the Care and Use of Laboratory Animals.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core facility that provides the following services: Sorting or analysis with operator service, Calcium flux measurements service, DNA analysis service, Cell sorting service.

This lab''s mission is to provide high standard cell sorting and analysis services to the research community at the Brigham and Women?s Hospital and the Longwood Medical area.

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• SciCrunch
• 13 years ago - by Anonymous

ETSG serves University of Chicago faculty led research projects. ETSG staff is available to help plan, design, build, test, and install mechanical and electro mechanical apparatus.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

In recognition of the value of small animal imaging to the research community, Children''s Hospital Boston has committed to developing a state-of-the-art Small Animal Imaging Laboratory. The SAIL facility is located within the Department of Radiology''s Kresge Laboratory.

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• SciCrunch
• 13 years ago - by Anonymous

Project to develop and utilize imaging infrastructure to create human brain cell census and instantiate it in coordinate system that will enable immediate impact of all in vivo MRI studies of human brain. Consortium for creating cellular census of human cerebral cortex.

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• RRID
• 4 years ago - submitted by Leah Morgan

Out of service. Documented on May,04,2021. This record has been removed from eagle-i search; this page is an archival copy only. Imaging Services offers high-quality poster printing.

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• SciCrunch
• 13 years ago - by Anonymous

Core provides statistical and big data analysis support. Performs data analysis and manuscript preparation services in Biostatistics, such as statistical genetics, longitudinal, survival, and high-throughput/high-dimensional omics data analysis; and Bioinformatics, such as DNA- and RNA-seq alignment, single cell DNA- and RNA-seq analysis, variant calling, differential expression and pathway analysis, data integration, online data submission, and custom script writing. Provides training to lab staff to enable them to perform future analyses.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Core facility that provides the following services: Illumina Gene Expression, Affymetrix gene expression. The Partners HealthCare Center for Personalized Genetic Medicine Microarray Facility is a full service facility dedicated to providing analysis for DNA or RNA samples. We provide support for high density microarrays to the Harvard Partners research community, including Harvard medical School, hospitals in the Partners Healthcare network, investigators in the Dana-Farber/Harvard Cancer Center, and the Harvard School of Public Health. Our services are open to both the PHS and non-PHS community.

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• SciCrunch
• 13 years ago - by Anonymous

ATTENTION: The 1000 Functional Connectomes Project has a new home page at NITRC. Please visit us at:http://fcon_1000.projects.nitrc.orgThis is the parent project for ABIDE, ADHD-200 (ADHD200), INDI, CORR, NKI-Rockland (NKI), Healthy Brain Network (HBN) and other projects.

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• NIF
• 4 years ago - by Anonymous

Core facility that provides the following services: Sperm Cryoperservation - Standard Mouse Backgrounds; including quality test (QC), 129 or Hybrid ES Cell transfection package for conventional or BAC vector (from DNA transfection to DNA preparation) ~200 colonies, C57BL/6 (JM8A) ES Cell transfection package for conventional or BAC vector (from DNA transfection to DNA preparation) ~200 colonies, Microinjection of one targeted 129, JM8A, or hybrid ES Cell clone, Microinjection of one targeted C57BL/6 (JM8 & others) ES Cell clone, Transgenic / DNA pronuclear Microinjection, Transgenic/ BAC DNA pronuclear Microinjection to hybrid mouse strain, Mice colony breeding, Mice ID tag & tail biopsy, Mice tail DNA preparation, Sperm Cryoperservation - Non-Standard Mouse Backgrounds; including quality test(QC), Recovery live born pups for testing following QC, IVF recovery of one mouse line from cryopreserved sperm for most strains (~10 pups provided), Recovery of cryopreserved mice embryos (up to 80 embryos), Special DNA Prep.

The MGH Transgenic and Gene Targeting Facility generates transgenic and knockout or knock-in mice to study gene function in embryonic stem cell and somatic cell systems. Services include: microinjection of DNA into fertilized embryos for the creation of transgenic mice, transfection of DNA into ES cells for the generation of recombinant ES cell clones, injection of gene-targeted ES cell clones into host blastocysts for the generation of gene knockout or knock-in mice, and other related ES cell based services. The facility is also equipped to perform in vitro fertilization projects, cryopreservation of mouse sperm and embryos, recovery of cryopreserved mouse sperm and embryos, and derivation of ES cell lines from a variety of genetic backgrounds. The facility provides consultation within reason on experimental design and vectors for gene targeting-related projects. The facility can also provide advice for the preparation of DNA, recombinant ES clones, mouse genotyping, handling and husbandry. The facility supports innovative and experimental approaches involving transgenic and knockout or knock-in mice to better help investigators study gene regulation and function, and develop appropriate animal models to study human genetic disorders.

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• SciCrunch
• 13 years ago - by Anonymous

Software R package for comprehensive visualization of genomic signal associations. Visualizes enrichment of genomic signals on specific target regions. Used to visualize e.g. how histone marks are enriched to specific sites.

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• RRID
• 4 years ago - by Anonymous

Study designed to test the hypothesis that African-Americans respond less well to combination pegylated interferon and ribavirin therapy than Caucasian-Americans who have chronic hepatitis C genotype 1 and who were not previously treated with either interferon or ribavirin. Reasons for differences in response, regardless of race, will be studied. All patients were treated with combination therapy of pegylated interferon and ribavirin for 48 weeks, and were followed for an additional 48 week safter cessation of therapy. 400 patients, half African-American and half Caucasian American, from 8 clinical centers with the goals of establishing rates of response to optimal current therapy in the two ethnic groups, identify factors predictive of response, establish patterns of viral kinetics in response to antiviral therapy, and test hypotheses concerning viral and host factors determining response to therapy. Four ancillary studies designed to elucidate biological and virological basis for non-response are also included in Virahep-C. Additionally, the study has central facilitates for pathology, the virological testing laboratory and a serum/tissue repository.

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• dkNET
• 14 years ago - by Anonymous

Core provides latest sequencing technology combined with Institute's expansive bioinformatics capabilities. Provides instrumentation including Illumina Miseq, Covaris Model E220, NovaSeq 6000, Agilent 2200 Tapestation, Beckman Coulter Biomek FXP, HiSeq 2500.

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• RRID
• 4 years ago - by Anonymous

A prospective, double-blind, randomized, sham-controlled, multi-center clinical trial that enrolls subjects who have received a prior cholecystectomy and are diagnosed with the clinical syndrome of Sphincter of Oddi Dysfunction III (SOD III) as defined by the Rome III criteria. The goal of the study is to asses the value of endoscopic sphincterotomy as a treatment for adult subjects categorized as SOD III suffering from pain after cholecystectomy and to define the role of manometry in treating these patients.

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• dkNET
• 14 years ago - by Anonymous

Sequencing Core offers Illumina next generation sequencing services to University of Pittsburgh research community. Offers expertise in next generation sequencing technologies. Encourages to contact Assistant Director to arrange for consultation.Staff is available to share their experience and expertise to assist with development of projects of all sizes, standard or custom assay design, and other specialized application needs.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

An integrative platform for diverse types of gene set analysis with annotation network navigation. It includes tools for statistical analysis, visualization of annotation relationships, retrieval of genes from annotation database, and set operation for gene sets. In an effort to allow access to a full spectrum of amassed biological knowledge, they have integrated a variety of annotation data that include the GO, domain, disease, drug, chromosomal location, and custom-defined annotations. Diverse types of molecular networks (pathways, transcription and microRNA regulations, protein-protein interaction) are also included. The pair-wise relationship between annotation gene sets was calculated using kappa statistics. GARNET consists of three modules--gene set manager, gene set analysis and gene set retrieval, which are tightly integrated to provide virtually automatic analysis for gene sets. A dedicated viewer for annotation network has been developed to facilitate exploration of the related annotations.

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• SciCrunch
• 13 years ago - by Anonymous

Used to store, publish and share research data in FAIR way. Facilitates research data storage, guarantees long-term persistence of data and allows data, results or ideas to be shared worldwide.Supports community domains with metadata extensions, access rules and publishing workflows.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth