Curator Dashboard

Facility that generates, analyzes, and interprets high-throughput genomic data to understand the genetic basis of disease. Genomics Platform has played leadership role in the design, data generation, and methods development in support of major genomic resource projects.Through the Broad Clinical Labs (BCL), formerly known as the Clinical Research Sequencing Platform (CRSP), it supports clinical trials, diagnostic testing, and major initiatives, including COVID-19 testing. Offers services including Nucleic Acid Extractions, Single Cell Sequencing (using 10x Genomics products), and GWAS Arrays.

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• dkNET
• 8 months ago - submitted by Maryann Martone

Biospecimen repository that provides scientists with the opportunity to bank their pluripotent stem cell lines and develops in-house induced pluripotent stem cell (iPSC) lines for distribution. They have developed core capabilities to maintain, characterize, bank, and distribute important stem cell resources. The SCB performs extensive identification and characterization testing for all submitted human induced pluripotent stem cell (iPSC) and mouse embryonic stem cell (mES) lines. The identification and quality control measures include karyotype analysis, microsatellite analysis for parental cell line identity matching, sterility testing, and assessment of viability after cryopreservation. Pluripotency characterizations performed by SCB vary depending upon the distributing repository. * NIGMS iPSCs: Surface antigen expression, Embryoid body formation, Pluritest Gene Expression assay * NINDS iPSCs: Surface antigen expression, Embryoid body formation * NIA mES: Surface antigen expression, Embryoid body formation, Transgene induction Each characterized human iPSC line and mES line released for distribution is provided with a Certificate of Analysis, which includes information regarding characterization and quality of the line, images and links to original publications. The human iPSCs distributed by Coriell are strictly for research purposes and cannot be used in human subjects. All terms described in the Material Transfer Agreement (NIGMS and NINDS Repositories) or Assurance Form (NIA Repository) for the stem cell line must be agreed to prior to using stem cell lines from Coriell.

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• SciCrunch
• 16 years ago - by Anonymous

EPSRC is the main UK government agency for funding research and training in engineering and the physical sciences, investing more than £850 million a year in a broad range of subjects from mathematics to materials science, and from information technology to structural engineering. We support research into engineering, mathematics, physics, chemistry, materials science, information and communications technologies. EPSRC is a non-departmental public body funded by the UK government through the Department for Universities, Innovation and Skills. We employ around 300 staff in Swindon. We manage our portfolio through programmes. Research base programmes focus on investigator-led research and training. Business innovation programmes deliver our priority research themes and maximise the economic and social impact of the research and training we fund.

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• SciCrunch
• 16 years ago - submitted by Andrea Stagg

Software R package providing functions to assist cellular neighborhood analysis of any spatial transcriptomics data with single-cell resolution. Spatial cellular neighbourhood scanning in R.

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• RRID
• 7 months ago - by Anonymous

Aggregator of blogs about new developments in science and other fields that allows readers to easily find blog posts about serious peer-reviewed research, instead of just news reports and press releases. If you''re a blogger who writes about serious research, Research Blogging offers you a way to distinguish your serious posts from news, politics, family, bagpipes, and so on. They can direct your regular readers - and new readers - to the posts you''ve worked the hardest to create. All you need to get started is a blog and a peer-reviewed research report that you''d like to discuss. How it works * Bloggers -- often experts in their field -- find exciting new peer-reviewed research they''d like to share. They write thoughtful posts about the research for their blogs. * Bloggers register and use a simple one-line form to create a snippet of code to place in their posts. This snippet not only notifies this site about their post, it also creates a properly formatted research citation for their blog. * Their software automatically scans registered blogs for posts containing their code snippet. When it finds them, it indexes them and displays them on their front page -- thousands of posts from hundreds of blogs, in one convenient place, organized by topic. * Their editors identify the notable posts in each major discipline, publishing the results on their news page. * Other services like PubGet index their database as well, so every time readers search for a journal article, they can also locate blog posts discussing the article. * The quality of the posts listed on their site is monitored by the member bloggers. If a post doesn''t follow their guidelines, it is removed from their database. Borderline cases may be discussed publicly on the blog as well. Bloggers are also provided with an icon they can use to show when they''re talking about a peer-reviewed work that they''ve read and analyzed closely. There are already over seven thousand blog posts using the icon, and now it''s easier than ever to find them.

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• SciCrunch
• 15 years ago - by Anonymous

A funding agency of the Australian government which supports research across the full spectrum of health and medical research, from basic science through to clinical, public health and health services research.

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• SciCrunch
• 17 years ago - submitted by Andrea Stagg

Core facility provides infrastructure and services to academic researchers, biotech companies and industry partners that need vectors or cell culture models for their studies. Focuses on generating cell models, genetic modification, viral vector development, and advanced flow cytometry analysis.

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• RRID
• 7 months ago - by Anonymous

An algorithm to estimate isoforms expression from RNA-seq data based on a model that doesn''t assume uniform distribution of count within transcripts.

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• SciCrunch
• 13 years ago - by Anonymous

Nonprofit American medical research facility that focuses on research and education in the biomedical sciences. Headquartered in San Diego, California with a sister facility in Jupiter, Florida, the institute has laboratories employing scientists, technicians, graduate students, and administrative and other staff, making it the largest private, non-profit biomedical research organization in the United States and among the largest in the world.

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• SciCrunch
• 17 years ago - by Anonymous

Vectorology Core Facility (part of the Cellular Engineering and Vectorology platform) provides specialized, high-level expertise, tools, and services for designing, producing, and validating viral vectors used in neuroscience research and gene therapy development. It supports academic and industrial partners by generating modified, safe viral vectors (e.g., AAV, lentivirus) for gene transfer and cellular, including human iPS, engineering.

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• RRID
• 7 months ago - submitted by Blandine Bonnamy

An MRI data set that demonstrates the utility of a mega-analytic approach by identifying the effects of age and gender on the resting-state networks (RSNs) of 603 healthy adolescents and adults (mean age: 23.4 years, range: 12-71 years). Data were collected on the same scanner, preprocessed using an automated analysis pipeline based in SPM, and studied using group independent component analysis. RSNs were identified and evaluated in terms of three primary outcome measures: time course spectral power, spatial map intensity, and functional network connectivity. Results revealed robust effects of age on all three outcome measures, largely indicating decreases in network coherence and connectivity with increasing age. Gender effects were of smaller magnitude but suggested stronger intra-network connectivity in females and more inter-network connectivity in males, particularly with regard to sensorimotor networks. These findings, along with the analysis approach and statistical framework described, provide a useful baseline for future investigations of brain networks in health and disease.

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• SciCrunch
• 15 years ago - by Anonymous

A service-provider company specialized in developing and managing scientific research projects. Its mission is to support research activities from the idea to the realization of project. ALTA assists in finding the proper strategy, building European Consortia and putting science in the most appropriate administrative and management framework.

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• SciCrunch
• 13 years ago - by Anonymous

Provides technical, on-the-job training to build expertise in water management. Provides research, and training in water science, policy, and management to foster sustainable, community-driven water solutions across Eastern and Southern Africa.

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• SciCrunch
• 7 months ago - submitted by Edyta Vieth

A tool for finding dbGaP studies containing phenotype variables of interest. Lack of standardization makes locating and categorizing previously measured variables difficult. This query tool for biomedical researchers is to identify studies and phenotype variables of interest.

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• SciCrunch
• 14 years ago - by Anonymous

CMC Microsystems enables and supports the creation and application of micro- and nano-system knowledge by providing a national infrastructure for excellence in research and a path to commercialization of related devices, components and systems. CMC Microsystems provides the tools, technologies and services that make microsystems research and development possible in universities across Canada. CMC delivers innovative and cost-effective services to a growing community of microsystems researchers that connect 43 universities and one college across Canada, and presently involves over 3,100 faculty and graduate students. A 4th Pillar organization stimulating synergistic collaboration among universities, companies and government agencies, CMC is a pioneer in developing creative solutions including Canada-wide Internet-based access to advanced microsystems testing facilities-at a fraction of the cost of conventional methods. Over the last five years, CMC delivered a value of 342 million to Canadian universities. Throughout the last 25 years CMC has successfully demonstrated the ability to specify, acquire and distribute all the necessary tools and technologies to design, make and test microsystems devices, components and systems and in the last five years has significantly expanded its skill base and partnerships. CMC has also developed a series of key relationships with suppliers which have enabled smooth and uninterrupted access to the latest tools and technologies. The governance structure is widely viewed as one of the soundest among organizations of this type and the management team of five people has a total experience of well over 100 years in the microsystems field.

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• SciCrunch
• 17 years ago - by Anonymous

Core provides access to cost effective instrumentation, software, and scientific consultation. First-come first-serve, fee-for-service core facility with fulltime staff to help users generate rigorous scientific data. Offers two point-scanning confocal microscopes, Nikon A1R and Zeiss LSM900, LSRFortessa X-20 and MACSQuant 10 analytic flow cytometers and 4 laser Sony MA900 cell sorter.

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• SciCrunch
• 7 months ago - submitted by Edyta Vieth

THIS RESOURCE IS NO LONGER IN SERVCE, documented September 22, 2016. Software application that provides analysis tools for the detection of shifts in relative allele frequency between pooled genomic DNA from cases and controls using SNP-based genotyping microarrays. GenePool supports genotyping platforms from Affymetrix and Illumina.

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• SciCrunch
• 14 years ago - by Anonymous

Netherlands institute for permanent access to digital research resources. DANS encourages researchers to make their digital research data findable, accessible, interoperable and reusable. It does this by providing expert advice and certified services.

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• SciCrunch
• 13 years ago - by Anonymous

Facility provides infrastructure and technical expertise for maintenance, breeding, and experimental use of Danio rerio. The facility ensures standardized husbandry, health monitoring, and traceability of zebrafish lines in compliance with regulatory and ethical guidelines. Services include colony management, maintenance and distribution of wild-type, mutant, and transgenic lines, and support for experimental workflows. The platform offers technical services such as embryo microinjection (e.g., genome editing using CRISPR/Cas9), phenotypic screening, fin clipping for genotyping, and in vitro fertilization. Training and technical support are available for zebrafish handling, experimental design, and data reproducibility.

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• RRID
• 6 months ago - submitted by Noémie Frère

Software application that is a Windows-based system designed for pedigree data management, providing a graphical interface for pedigree construction and output. (entry from Genetic Analysis Software)

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• SciCrunch
• 14 years ago - by Anonymous