We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Core provides Genomics, Transcriptomics and Proteomics Services to researchers.
Software application as implementation of ASCAT allowing generation of CNV profiles from single cell and short coverage sequencing data.
Ontology that describes the content of the models used in medical image simulation developed in the context of the Virtual Imaging Platform project (VIP), a french project aiming at sharing medical image simulation resources. This ontology can be used to annotate such models in order to highlight the different entities that are present in the 3D scene to be imaged, i.e. anatomical structures, pathological structures, foreign bodies, contrast agents etc. The model allows also to associate to these entities information about their physical qualities, which are used in the medical image simulation process (to mimick physical phenomena involved in CT, MR, US and PET imaging). This ontology partly relies on the OntoNeuroLOG ontology (ONL-DP ONL-MR-DA), as well as PATO, RadLex, FMA and ChEBI.
Software R package provides functions for creating and customizing ggplot2 based publication ready plots.Used for creation of ggplot2 based graphs.
Core facility provides technical services including transgenic breeding, chemical carcinogenesis treatment, tumourigenicity studies in nude mice and quarantine facilities to allow the import of animals from both Europe and other countries.
An ontology for describing biological activities of natural products.
Cryo-electron microscopy (cryo-EM) facility providesTitan Krios cryo-transmission electron microscope that is fully equipped for high-throughput data collection of the utmost quality possible. It has the ability to determine the atomic structure of a single protein or view molecules interacting in their cellular context. Provides guidance, training or data collection for researchers at the College of Medicine.Equipment includes Zeiss LSM 980 Cryo-Confocal Microscope,300 kV Krios Cryo-TEM for SPA and tomography, Equipped with Volta phase plates, bioquantum energy filter and K3 direct electron detector,200 kV thermionic JEOL 2100 for cryo-imaging, cryo-tomography, and standard imaging of stained grids.
Core provides analytic expertise and infrastructure needed to transform complex spatial data into actionable insights to support cancer research, precision population health, learning health system interventions and policy and resource planning at institutional and regional levels.
Generic ontology for the domain of data mining that includes the information processing processes that occur in the domain of data mining, participants in the processes and their specifications. OntoDM is highly transferable and extendable due to its adherence to accepted standards, and compliance with existing ontology resources. The generality in scope allows wide number of applications of the ontology, such as semantic annotation of data mining scenarios, ontology based support for QSARs, etc.
Portal allows researchers and clinicians to access and work across multiple Common Fund program data sets within digital cloud environment because biomedical research interaction with digital data is changing and no longer can large biomedical datasets be stored or analyzed using local computers and servers. Provides list of tutorials and resources to learn how to perform bioinformatic analyses and access data.
Core scientists collaborate with research teams from a variety of disciplines and institutions. MATR services include recruitment, data and sample collection, dataset curation and access, protocol development, cost estimates, grant development support, and IRB submissions. Twins and their families who are willing to consider taking part in twin-based, health-related research can participate. For twins of any age, ethnicity, and zygosity (identical or fraternal), as well as higher order multiples such as triplets, quadruplets and quintuplets. Most of twins registered in MATR are from Virginia, North Carolina, and South Carolina, but twins from all over the country and all around the world are welcome to register. MATR repository containing DNA samples provided by twins and allows to study twin data collected by studies along with their DNA.
A controlled vocabulary of growth and developmental stages in various plants. Note that this has been subsumed into the Plant Ontology (PO). This file is created by filtering plant_ontology_assert.obo to contain only terms from the plant structure development stage branch of the PO. For more information, please see: http://palea.cgrb.oregonstate.edu/viewsvn/Poc/tags/live/
GNU Project shell. Sh-compatible shell that incorporates useful features from Korn shell (ksh) and the C shell (csh). Improvements offered by Bash include command-line editing, unlimited size command history,job control,shell functions and aliases,indexed arrays of unlimited size,integer arithmetic in any base from two to sixty four.
Provides manufacturing micro- and nanofluidic devices for biomedical research, equipment and resources for applications with micro- and nanofabrication needs. Facility conisists of ISO class 7 cleanroom space, housing tools and materials for techniques including photolithography, nano-imprint lithography, plasma (dry) etching (ICP-RIE), wet etching, thin film deposition, scanning electron microscopy (VP-SEM), atomic force microscopy, contact angle goniometry, ellipsometry, profilometry, wafer dicing, wire bonding, laser ablation and engraving, 3D printing, hot embossing, and COMSOL software for device modeling. In addition, the facility has numerous microscopes for general inspection, ovens and furnaces, ultrapure water, and dedicated process fume hoods.
A domain ontology that provides a formal representation (OWL-DL) of genomic variations. Despite its name it is not limited to the representation of SNPs but it encompasses genomic variations in a broader meaning. SNP-Ontology is general enough to enable the representation of variations observed in genome of various species. Latest versions of SNP-Ontology include the representation of haplotype and of CNV. The unambiguous representation of genomic variations provided by SNP-Ontology enables to integrate heterogeneous data related to genomic variations. To achieve this goal SNP-Ontology enables (1) to represent one variation in accordance with various ways that exist for describing it, (2) to represent the equivalence between two distinct descriptions of one variation, and (3) to represent correspondence between a genomic variation and its outcome at the transcriptome and proteome levels.
Genomics Section provides services and instrumentation that enable DNA/RNA extraction and quality control, next-generation Illumina and Nanopore sequencing, epigenetic profiling, and microarray analysis on a whole-genome scale, from the level organisms to single cells. Molecular Biology Section provides DNA fragment analysis qPCR, Sanger sequencing and NanoString Technology.
Core offers a variety of preclinical imaging services. Small animal imaging core facility with high-resolution ultrasound (FujiFilm, Vevo F2, Visual Sonics) and micro CT (SkyScan 1276 (Bruker), micro CT with in vivo and ex vivo capabilities, Caliper IVIS Lumina LT (Revvity). Offers complete services for non-destructive, longitudinal optical imaging with bioluminescence and fluorescence capabilities of mice.
A multi-species anatomical ontology for the vertebrate lineage, developed as part of the Bgee project. The mapping to species-specific anatomical ontologies is provided as a separated file: http://bgee.unil.ch/download/organ_association_vHOG.txt This mapping represents homology-strict relationships, in the sense of HOM:0000007 historical homology. Each mapping has been manually reviewed, and theye provide confidence codes and references when available.
Portal within Wikipedia platform for presenting content, tools, and discussion related to clinical trials.Anyone can join to express their interest in developing content in Wikidata related to clinical trials.
Core provides access to biophysical and biochemical instrumentation focused on the study of conformations, activities, and assembly of biological and other macromolecules.