Curator Dashboard

Database for genomes that have been completely sequenced, have active research community to contribute gene-specific information, or that are scheduled for intense sequence analysis. Includes nomenclature, map location, gene products and their attributes, markers, phenotypes, and links to citations, sequences, variation details, maps, expression, homologs, protein domains and external databases. All entries follow NCBI's format for data collections. Content of Entrez Gene represents result of curation and automated integration of data from NCBI's Reference Sequence project (RefSeq), from collaborating model organism databases, and from many other databases available from NCBI. Records are assigned unique, stable and tracked integers as identifiers. Content is updated as new information becomes available.

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• SciCrunch
• 16 years ago - by Anonymous

Software R package providing missing functionality to ggplot2 through extension system introduced with ggplot2 v2.0.0.

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• RRID
• 4 years ago - by Anonymous

Database that summarizes diverse information about metabolic pathways in crop plants and allows automatic export of information for the creation of detailed metabolic models. It contains manually curated, highly detailed information about metabolic pathways in crop plants, including pathway diagrams, reactions, locations, transport processes, reaction kinetics, taxonomy and literature. It contains information about seven major crop plants with high agronomical importance and two model plants.

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• SciCrunch
• 17 years ago - by Anonymous

Provides advanced light microscopy services for biomedical and translational research including workflow, training for independent work, assistance and technical support in microscopy techniques, quantitative image analysis. Offers training and support for imaging and analyzing gels and blots.

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• SciCrunch
• 4 years ago - submitted by Cassie Sather

Agency that produces evidence to make health care safer, higher quality, more accessible, equitable, and affordable. Funding opportunities, grants, and a large collection of longitudinal hospital care data in the United States including the Systematic Review Data Repository and data sources on healthcare cost, quality, and accessibility, emergency room visits, hospitalization, and medical insurance are available. It works within the U.S. Department of Health and Human Services and with other partners to make sure that the evidence is understood and used.

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• SciCrunch
• 13 years ago - by Anonymous

Offers imaging techniques using imaging and measurement tools. Offers consulting services ranging from educational seminars to assistance with grant and industry funding support.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Public registry of nucleic acid reagents designed for use in a wide variety of biomedical research applications including genotyping, gene expression studies, SNP discovery, genome mapping, and gene silencing. Probe records contain information on reagent distributors, probe effectiveness, and computed sequence similarities. The database is constantly updated, with over 11,000,000 probes available. Users may deposit their data into NCBI Probe Database.

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• SciCrunch
• 13 years ago - by Anonymous

Offers comprehensive CRISPR services to generate gene edited rodents and cells, and helps generate transgenic and chimeric mice via our microinjection service, cryopreserving unique mouse lines, and recovering them from liquid nitrogen storage via IVF and embryo transfer services.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

A multidisciplinary repository of public data sets such as the Human Genome and US Census data that can be seamlessly integrated into AWS cloud-based applications. AWS is hosting the public data sets at no charge for the community. Anyone can access these data sets from their Amazon Elastic Compute Cloud (Amazon EC2) instances and start computing on the data within minutes. Users can also leverage the entire AWS ecosystem and easily collaborate with other AWS users. If you have a public domain or non-proprietary data set that you think is useful and interesting to the AWS community, please submit a request and the AWS team will review your submission and get back to you. Typically the data sets in the repository are between 1 GB to 1 TB in size (based on the Amazon EBS volume limit), but they can work with you to host larger data sets as well. You must have the right to make the data freely available.

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• SciCrunch
• 14 years ago - by Anonymous

Software R package for exploratory data analysis and data visualization for biological sequence, DNA and protein, data.

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• RRID
• 4 years ago - by Anonymous

Longitudinal datasets of demographic, social, medical and economic information from a rural demographic in northern KwaZulu-Natal, South Africa where HIV prevalence is extremely high. The data may be filtered by demographics, years, or by individuals questionnaires. The datasets may be used by other researchers but the Africa Centre requests notification that anyone contact them when downloading their data. The datasets are provided in three formats: Stata11 .dta; tables in a MS-Access .accdb database; and worksheets in a MS-Excel .xlsx workbook. Datasets are generated approximately every six months containing information spanning the whole period of surveillance from 1/1/2000 to present.

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• SciCrunch
• 14 years ago - by Anonymous

Core performs expression profiling, SNP genotyping and copy number microarray (Thermo Fisher) services.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

A Windows (Win32) software application for montaging, aligning, tracing, measuring, and reconstructing objects from serial microscopic section images. The software is designed for microscopy in which section resolution is much less than section thickness, such as transmitted electron microscopy (EM) where the resolution is a few nanometers while the section thickness is many tens of nanometers. Reconstruct can easily handle series with hundreds of very large, high-resolution section images. It facilitates image cropping, scaling and alignment. Multiple images can be placed side-by-side to make a montage of a section from a mosaic of images. The alignment of adjacent sections can be rapidly compared by either blending the two sections or by flickering between them. Sections can be moved while blended. Reconstruct aids in the calibration of image size. Images taken at different magnifications can be combined, calibrated and aligned. Tools for tracing and editing of objects on sections are provided. Objects can be surfaced from the traces and previewed in an OpenGL-based 3D scene window. The 3D scene can be saved as a bitmap or as a VRML file.

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• SciCrunch
• 17 years ago - by Anonymous

Supports leading edge research with free access to advanced computing hardware and software.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core facility that provides the following services: Tissue trimming, cassetting, processing, and embedding, Cutting and staining of paraffin-embedded and cryostat sections, Immunohistochemistry for both routine and novel markers, In situ hybridization, using chromogenic or radioactive detection methods, Laser capture microdissection.

Tissue analysis is critical to validation and evaluation of animal models of human cancer, and human cancer tissues serve as the operating system for translational research. The facility supports a wide spectrum of cancer-relevant research, from basic studies on pathogenic mechanisms in cancer to translational research focused on the development of new tests for biomarkers that stratify patients and direct therapy. The Specialized Histopathology (SHP) Core, was created in 2005 by consolidating five histopathology cores into a single unit with two performance sites: Longwood, Directed by Jon Aster and based at the Brigham and Women?s Hospital and MGH, Directed by Anat Stemmer-Rachamimov and based at Massachusetts General Hospital East in Charlestown. The SHP Core provides professional and technical research pathology services to DF/HCC investigators working in diverse organisms (e.g., rodents, fish, and monkeys) or human tissues. The Core also assists in experimental design and the development and interpretation of tests and their results. As of July 2012, the Longwood site offers CLIA Certified services.

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• SciCrunch
• 13 years ago - by Anonymous

Core provides access to light microscope systems to perform widefield, confocal, 2-photon/multiphoton, second harmonic generation, total internal reflection (TIRF), and high content imaging.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 13, 2026. Bookmarklet suitable for all main browsers, that, when invoked, highlights concepts of scientific significance in text and offers links to many open information resources about any concept highlighted.

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• SciCrunch
• 13 years ago - by Anonymous

Provides service for production and purification of custom antibodies.Primary services include immunization of mice and rabbits to make mouse and rabbit monoclonal antibodies to select targets. Primary screening of hybridomas will be conducted using standard ELISA technology and positive lines will be preserved for cloning. Supernatants containing antibody selected as positive will be made available to investigators for secondary analyses in their labs (Westerns, immunofluorescence, functional assays). Investigator selected lines will be cloned, isotyped, and adapted to serum free culture for future production of high titer antibody if investigator requires large quantities of antibody. Standard purifications will be conducted as needed, and various modifications (fluorochrome, enzyme, biotin) are also provided as Antibody Core services.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

An ontology that aims to establish a standard in representing chemical information including chemical structure and the ability to richly describe chemical properties, whether intrinsic or computed. It includes terms for the descriptors commonly used in cheminformatics software applications and the algorithms which generate them.

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• SciCrunch
• 13 years ago - by Anonymous

Software tool as statistical framework for identifying distribution shapes in single-cell RNA-sequencing data.

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• RRID
• 4 years ago - submitted by Malindrie Dharmaratne