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British charity and fundraiser for cardiovascular research.
The Research Computing System is a vision for a user controlled collection of applications, tools, and services integrated through a uniform understanding of user identity and the communities (groups) to which the user belongs. This environment enables seamless access to shared resources and facilitates collaborations within departments, across campus and around the globe. The RCS development project is a collaborative effort to build a private cloud to support the construction and operation of research applications. RCS is the collection of these resources and the communities surrounding their development. RCS is an open development effort that welcomes participation of those interested in the construction, use, or operation of this platform.
Software performing alignment of high-throughput RNA-seq data. Aligns RNA-seq reads to reference genome using uncompressed suffix arrays.
An independent, not-for-profit consortium to accelerate research, and improve treatment for patients affected with the most commonly-diagnosed cancers in Asia by generating a genomic data resource for the most prevalent cancers in Asia. ACRG is focusing its initial efforts on Asian liver, gastric and lung cancers. Goals * Generate comprehensive genomics data sets for Asia-prevalent cancers * Conduct all research under good clinical practices and in accordance with local laws * Uncover key mutations and pathways for developing targeted therapies * Discover molecular tumor classifiers for patient stratification * Discover prognostic markers to identify high-risk patients * Freely share resulting raw data with scientific community to empower researchers globally and enable development of new diagnostics and medicines * Publish data analysis results jointly in prominent scientific journals Over the next two years, Lilly, Merck and Pfizer have committed to create an extensive pharmacogenomic cancer database that will be composed of data from approximately 2,000 tissue samples from patients with lung and gastric cancer that will be made publicly available to researchers and, over time, further populated with clinical data from a longitudinal analysis of patients. Comparison of the contrasting genomic signatures of these cancers could inform new approaches to treatment. Lilly has assumed responsibility for ultimately providing the data to the research public through an open-source concept managed by Lilly''''s Singapore research site. Moreover, Lilly, Merck and Pfizer will each provide technical and intellectual expertise. One dataset can be found at http://gigadb.org/dataset/100034
The European Clinical Research Infrastructures Network (ECRIN) is focused on synergizing and connecting the clinical research capabilities within the European continent.
A software pipeline for building loci from short-read sequences, such as those generated on the Illumina platform. It was developed to work with restriction enzyme-based data, such as RAD-seq, for the purpose of building genetic maps and conducting population genomics and phylogeography.
THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 19, 2022.The mission of the Human Antibody Initiative (HAI) aims to promote and facilitate the use of antibodies for proteomics research. The initiative consists of two separate activities; (1) the generation of a catalogue of validated antibodies from many different sources and (2) a protein atlas for the expression and localization of human proteins in normal and disease tissue. The two separate activities have as their primary deliverables to generate databases with free public accessibility. The Antibody Resource database (www.antibodypedia.org) is aimed to produce a comprehensive catalogue of validated antibodies towards human proteins. This initiative depends on input from a large number of academic groups and commercial companies. The Protein Atlas initiative (www.proteinatlas.org) is aimed to provide comprehensive and annotated database of high-resolution images showing tissue profiles in normal and cancer tissues. Both databases will be open to the public without restriction (no passwords).
A worm atlas that provides an interactive 4D atlas of nuclear positions, from zygote until hatching which can be used to guide cell identification. The tools enable examination of the connectome during development from integrate knowledge of C. elegans embryogenesis to widely used resources, such as WormAtlas and WormBase.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. High-throughput sequence alignment tool that aligns short DNA sequences (reads) to the whole human genome at a rate of over 1500 million 60bps reads per hour, which is one to two orders of magnitudes faster than the leading state-of-the-art techniques. Feature list for the current version (v 0.1.5) of WHAM: * Supports paired-end reads * Supports up to 5 errores * Supports alignments with gaps * Supports quality scores for filtering invalid alignments, and sorting valid alignments * finds ALL valid alignments * Supports multi-threading * Supports rich reporting modes * Supports SAM format output
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 1, 2019. The first brain atlas for the common marmoset to be made available since a printed atlas by Stephan, Baron and Schwerdtfeger published in 1980. It is a combined histological and magnetic resonance imaging (MRI) atlas constructed from the brains of two adult female marmosets. Histological sections were processed from Nissl staining and digitized to produce an atlas in a large format that facilitates visualization of structures with significant detail. Naming of identifiable brain structures was performed utilizing current terminology. For the present atlas, an adult female was perfused through the heart with PBS followed by 10% formalin. The brain was then sent to Neuroscience Associates of Knoxville, TN, who prepared the brain for histological analysis. The brain was cut in the coronal (frontal) plane at 40 microns, every sixth section stained for Nissl granules with thionine and every seventh section stained for myelinated fibers with the Weil technique. The mounted sections were photographed at the NIH (Medical Arts and Photography Branch). The equipment used was a Nikon Multiphot optical bench with Zeiss Luminar 100 mm lens, and scanned with a Better Light 6100 scan back driven by Better Light Viewfinder 5.3 software. The final images were saved as arrays of 6000x8000 pixels in Adobe Photoshop 6.0. A scale in mm provided with these images permitted construction of the final Nissl atlas files with a horizontal and vertical scale. Some additional re-touching (brightness and contrast) was done with Adobe Photoshop Elements 2.0. The schematic (labeled) atlas plates were created from the Nissl images. The nomenclature came almost exclusively from brainmaps.org, where a rhesus monkey brain with structures labeled can be found. The labels for the MRI images were placed by M. R. Zametkin, under supervision from Dr. Newman.
A web application which provides public access to scientific literature through text and data mining.
Software R package for developing heart rate variability analysis. Allows to import data files containing heartbeat positions in broadly used formats; eliminating outliers or spurious points present in time series with unacceptable physiological values; plotting HRV data and performing time domain, frequency domain and nonlinear HRV analysis.
The NAMM Foundation is a non-profit organization with the mission of advancing active participation in music making across the lifespan by supporting scientific research, philanthropic giving and public service programs from the international music products industry. FOUNDATION ACTIVITIES: * Research: The NAMM Foundation provides support for projects that explore the impact of active music making during various stages of life and on human experience and conditions. The Foundation then promotes this research through the media to educate people of all ages about the proven benefits of playing music. * Program Grants: The NAMM Foundation supports innovative community-based music learning programs that allow more people the opportunity to experience the proven benefits of active music making. In 2010, the NAMM Foundation provided close to $600,000 in grants to worthy organizations and programs. * Wanna Play Fund: Wanna Play? is a public education campaign designed by NAMM in 2006 to raise awareness of the many benefits of music making and inspire people of all ages and talent levels to become active music makers. Initiated in September 2009, the Foundation''s Wanna Play Fund seeks public donations for programs and activities that expand access to music education and participation in music making for people of all ages. Donations to the Wanna Play Fund will be used to provide musical instruments to schools that are expanding or re-instating music education programs. * The Museum of Making Music: The mission of the Museum of Making Music is to celebrate the rich history and encourage the future of music making. The one-of-a-kind museum invites all NAMM Members to tour the Museum FREE of charge. Located in the NAMM Industry Headquarters in beautiful Carlsbad, Calif., the museum is a great way to experience first-hand the impact of the music products industry over the last 100 years. For more information about the museum or its activities, call 877-551-9976 or visit www.museumofmakingmusic.org. * SupportMusic Coaltion and Music Education Advocacy: The NAMM Foundation seeks to strengthen music education in schools and communities nationwide through its SupportMusic Coalition and website. Music and the arts are vital to every child''s education. SupportMusic provides tools and resources to advance community support for music education with the idea that local parents, teachers, students and advocates CAN make a difference! The NAMM Foundation also annually releases a list of the ������??Best Communities for Music Education������?? honoring schools that demonstrate a strong commitment to music and arts as part of a well-rounded education for every child.
Repository for metabolomics data and metadata which provides analysis tools and access to various resources. NIH grantees may upload data and general users can search metabolomics database. Provides protocols for sample preparation and analysis, information about NIH Metabolomics Program, data sharing guidelines, funding opportunities, services offered by its Regional Comprehensive Metabolomics Resource Cores (RCMRC)s, and training workshops.
Software package as decision algorithms for solving binary classification problems. Faster and more frugal because every node allows making decision. Apart from being faster and requiring less information, FFTs tend to be robust against overfitting, and are easy to interpret, use, and communicate.
Wiki investigating human genetics including information about the effects of variations in DNA, citing peer-reviewed scientific publications. It is used by Promethease to analyze and help explain your DNA. It is based on a wiki model in order to foster communication about genetic variation and to allow interested community members to help it evolve to become ever more relevant. As the cost of genotyping (and especially of fully determining your own genomic sequence) continues to drop, we''''ll all want to know more - a lot more - about the meaning of these DNA variations and SNPedia will be here to help. SNPedia has been launched to help realize the potential of the Human Genome Project to connect to our daily lives and well-being. For more information see the Wikipedia page, http://en.wikipedia.org/wiki/SNPedia * Download URL: http://www.SNPedia.com/index.php/Bulk * Web Service URL: http://bots.SNPedia.com/api.php
A funding resource which allows researchers to receive funding from citizen and organizational donors. Benefunder encourages relationships between the donor(s) and researcher(s) as well as wealth management which facilitates long-term funding and low overhead.
Ultrahigh resolution 3D human brain model at nearly cellular resolution of 20 micrometers, based on reconstruction of histological sections. Provides considerable neuroanatomical insight into human brain, thereby allowing extraction of microscopic data for modeling and simulation. Enables testing of hypotheses on optimal path lengths between interconnected cortical regions or on spatial organization of genetic patterning, redefining traditional neuroanatomy maps such as those of Brodmann and von Economo.
Seattle based independent, nonprofit medical research organization dedicated to accelerating the understanding of how human brain works. Provides free data and tools to researchers and educators and variety of unique online public resources for exploring the nervous system. Integrates gene expression data and neuroanatomy, along with data search and viewing tools, these resources are openly accessible via the Allen Brain Atlas data portal. Provides Allen Mouse Brain, Allen Spinal Cord Atlas, Allen Developing Mouse Brain Atlas, Allen Human Brain Atlas,Allen Mouse Brain Connectivity Atlas, Allen Cell Type Database, The Ivy Glioblastoma Atlas Project (Ivy GAP), The BrainSpan Atlas of the Developing Human Brain.
A database that contains different CSL citation styles. Styles can be searched by name, journal title, or by example and then viewed or installed. Users can also edit current styles and save them.