We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Polish governmental agency that administers governmental activities in science and higher education. Funding is provided by the state for scientific research.
Collection of molecular genetic reagents to gain access to many different brain cell types. Provides scientists with advanced genetic tools, primarily AAV (Adeno-Associated Virus) vectors with cell-type specific "enhancers," to precisely target, map, monitor, and manipulate specific cell types and circuits in the brain and spinal cord.
Software automated tool for analysis and determination of Nuclear Localization Signals (NLS). Predicts that your protein is nuclear or finds out whether your potential NLS is found in our database. The program also compiles statistics on the number of nuclear/non-nuclear proteins in which your potential NLS is found. Finally, proteins with similar NLS motifs are reported, and the experimental paper describing the particular NLS are given.
Royal Institute of Technology is a university in Stockholm, Sweden that has undergraduate, master's, and doctoral degree programs.
Standardized, open-source framework of classes and properties designed to annotate and interlink data regarding metabolites, species taxonomy, ecological traits, and environmental interactions. It powers the METRIN-KG knowledge graph, mapping the chemical diversity of Earth's species to support biodiversity conservation. Knowledge representation schema designed to capture, contextualize, and structure chemical diversity data across all known species. It reuses and harmonizes several existing ontologies, while introducing over 100 new concepts and relations to enable interoperability and data reuse.
NumPy is the fundamental package needed for scientific computing with Python. It contains among other things: * a powerful N-dimensional array object * sophisticated (broadcasting) functions * tools for integrating C/C and Fortran code * useful linear algebra, Fourier transform, and random number capabilities. Besides its obvious scientific uses, NumPy can also be used as an efficient multi-dimensional container of generic data. Arbitrary data-types can be defined. This allows NumPy to seamlessly and speedily integrate with a wide variety of databases. Sponsored by ENTHOUGHT
Globally recognized for certain specialities and ultra-specialities such as severe trauma, serious heart and pulmonary problems, and important mental illnesses.
Core provides services supporting generation, modification, cryopreservation, and rederivation of genetically modified rodent models for biomedical research, generates genetically modified mouse models via both targeted and random mutagenesis using tools such as CRISPR/Cas9 in zygotes or embryonic stem (ES) cells, provides cryopreservation and rederivation of existing animal models to preserve hygienic integrity. Services for rodent transgenic model development include: Pronuclear Injection and amp; Viral Transgenesis with introduction of genetic constructs into zygotes using microinjection or lentiviral systems; ES Cell-Based Techniques: use of embryonic stem cell manipulation for genetic targeting; Embryo Transfer: transferring manipulated embryos into recipient females; In Vitro Fertilization (IVF): assisted reproductive technology to generate embryos for manipulation or cryopreservation; Cryopreservation: freezing of embryos and sperm for archiving or rederivation of lines as required. Facility’s expertise includes quality control of cryopreserved material to ensure viability upon thawing.
Ensembl Genomes project produces genome databases for important species from across the taxonomic range, using the Ensembl software system. Five sites are now available, one of which is Ensembl Plants, which houses plant species. Sponsors: EnsembPlants is a project run by EMBL - EBI to maintain annotation on selected genomes, based on the software developed in the Ensembl project developed jointly by the EBI and the Wellcome Trust Sanger Institute.
The world''s largest private, nonprofit ocean research, engineering and education organization.
Core research service unit at the Charité – Universitätsmedizin Berlin specializing in laboratory animal husbandry, breeding, and experimental usage for biomedical research. Provides infrastructure for animal-based studies, ensures compliance with animal welfare regulations (e.g., training, veterinary oversight), and supports the creation of genetically modified models.
A permutation-based method (written in Python) for ascertaining genes with a somatic mutation distribution showing evidence of positive selection for non-silent mutations.
Research and development organization that hosts a knowledgebase in diverse scientific areas. It also hosts a network of national Indian laboratories, outreach centres, and innovation complexes.
Core provides services including processing and production of cell therapy products for clinical use, expertise in translation of cellular therapies to the clinic, and instrumentation supporting the development of novel immunotherapy strategies and insights on mechanisms of action for effective therapies.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 12,2023. Software application with implementation of the Sad statistic, more robust to transmission ratio distortion in the context of allele sharing (entry from Genetic Analysis Software)
One of 27 institutes and centers that make up the NIH, National Human Genome Research Institute (NHGRI) is devoted to advancing health through genome research. The Institute led NIH''s contribution to the Human Genome Project, which was successfully completed in 2003 ahead of schedule and under budget. Building on the foundation laid by the sequencing of the human genome, NHGRI''s work now encompasses a broad range of research aimed at expanding understanding of human biology and improving human health. The NHGRI''s mission has expanded to encompass a broad range of studies aimed at understanding the structure and function of the human genome and its role in health and disease. To that end NHGRI supports the development of resources and technology that will accelerate genome research and its application to human health. A critical part of the NHGRI mission continues to be the study of the ethical, legal and social implications (ELSI) of genome research. NHGRI also supports the training of investigators and the dissemination of genome information to the public and to health professionals.
Core dedicated to developing, characterizing, and distributing gene-edited rabbit models for biomedical studies. Team specializes in rabbit embryology, molecular biology, and animal reproduction, including developing Rabbit Gene Editing Technology (RbGET) workshops. Provides services including generating novel, customized gene-edited models (knockout/knock-in), and conducting preclinical, proof-of-concept studies to support drug development.
A tool for extraction and collaboration for data curation related to biology. CBioC runs as a web browser extension and allows unobtrusive use of the system during the regular course of research in PubMed. It can also be accessed directly (without having to install a plug-in). Automated text extraction is used as a starting point to bootstrap the database, but then it is up to biologists improve upon the extracted data, ironing out inconsistencies by subsequent edits on a massive scale. * After install, it loads when you visit PubMed. * Gets interactions from PubMed abstracts. * Allows you to vote and modify extracted data. * Also shows data from BIND, DIP, MINT, GRID, IntAct.
Sasakawa Memorial Health Foundation (SMHF) was established in 1974, with Mr. Ryoichi Sasakawa, founder and first chairman of the Nippon Foundation (TNF) as President, and Professor Morizo Ishidate, father of chemotherapy of Hansen''s Disease (HD) in Japan, as chair. The principal objective of SMHF is to eliminate HD, a disease which has struck fear into human beings for millennia and stigmatized those it touched. SMHF approaches HD not only as a public health problem but also as a social and human issue. Apart from HD, the work of SMHF covers many of issues within the realm of basic health needs. In doing so SMHF has always respected the ownership by the people, of their own health related needs. SMHF believes in sharing resources and knowledge, rather than creating a situation in which the ''haves'' give to the ''have-nots''. Through this we would like to share with you the joy of working together across national borders for the benefit of people in need. Sasakawa Memorial Health Foundation provides grants to projects implemented by non-profit organizations based outside of Japan. Funding Areas: Hansen''s disease (HD), Neglected Tropical Diseases (NTDs), and Palliative Care (For Japan based Applicants Only)
Project provides data currently generated with support from the NIH Brain Initiative Cell Atlas Network (BICAN). Broad Institute collaboration supported by the NIH BRAIN Initiative, to create comprehensive atlas of cellular variation in the healthy human brain. It maps data from millions of cells across diverse individuals to understand how brain biology differs, helping researchers distinguish healthy variation from disease states.