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National consortium of medical research institutions working together to transform the local, regional, and national environment to increase the efficiency and speed of clinical and translational research across the country. Consortium members share a common vision to reduce the time it takes for laboratory discoveries to become treatments for patients, to engage communities in clinical research efforts and to train clinical and translational researchers. This consortium includes 60 medical research institutions located throughout the nation, linking them together to energize the discipline of clinical and translational science. The CTSA consortium has five Strategic Goals: * National Clinical and Translational Research Capability * The Training and Career Development of Clinical and Translational Scientists * Consortium-Wide Collaborations * The Health of our Communities and the Nation * T1 Translational Research

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• SciCrunch
• 17 years ago - by Anonymous

Society of prestigious German research institutions that conduct basic research in the service of the general public in the natural sciences, life sciences, social sciences, and the humanities. Max Planck Institutes focus on research fields that are particularly innovative, or that are especially demanding in terms of funding or time requirements. And their research spectrum is continually evolving: new institutes are established to find answers to seminal, forward-looking scientific questions, while others are closed when, for example, their research field has been widely established at universities. This continuous renewal preserves the scope the Max Planck Society needs to react quickly to pioneering scientific developments.

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• SciCrunch
• 16 years ago - submitted by Andrea Stagg

World-renowned institution dedicated to ending cancer through expert, compassionate patient care, pioneering research, and education for adults and children with all types of cancer, combining cutting-edge science with a holistic approach to treatment and support. Its mission focuses on innovative diagnosis and treatment (surgery, chemo, radiation, immunotherapy), supportive care (nursing, counseling, rehab), and training future cancer leaders.

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• RRID
• 10 months ago - submitted by Edyta Vieth

The aim of this resource is to facilitate and promote, even through fund-raising, the scientific research for the treatment of Friederich''s Ataxia. The mission of this portal is to: - To distribute information to the people affected by the disease and to make the general population aware. - Promote, fund and support the diagnosis, research, cure and potential treatments. - Promote the cooperation with other voluntary associations both national and international. Sponsors: This resource is supported by the RUDI Committee. Keywords: Research, Diagnosis, Cure, Treatment, Disease, Scientific, Friederich''s Ataxia,

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• SciCrunch
• 17 years ago - by Anonymous

Leadership in the national effort to reduce alcohol-related problems. It does this by by: * Conducting and supporting research in a wide range of scientific areas including genetics, neuroscience, epidemiology, health risks and benefits of alcohol consumption, prevention, and treatment; * Coordinating and collaborating with other research institutes and Federal Programs on alcohol-related issues; * Collaborating with international, national, state, and local institutions, organizations, agencies, and programs engaged in alcohol-related work; and * Translating and disseminating research findings to health care providers, researchers, policymakers, and the public. The Institute''s efforts to fulfill its mission are guided by the NIAAA vision to support and promote, through research and education, the best science on alcohol and health for the benefit of all by: * Increasing the understanding of normal and abnormal biological functions and behavior relating to alcohol use; * Improving the diagnosis, prevention, and treatment of alcohol use disorders; and * Enhancing quality health care. Research opportunities to increase our understanding of why, how, and when people drink, and why and how some people develop alcohol use disorders, are set forth in the NIAAA Strategic Plan for Research

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• SciCrunch
• 17 years ago - submitted by Andrea Stagg

Open source resource of manually curated and expert reviewed infant brain segmentations hosted on OpenNeuro.org. and OSF.io. Anatomical MRI data was segmented from 71 infant imaging visits across 51 participants, using both T1w and T2w images per visit. Images showed dramatic differences in myelination and intensities across 1–9 months, emphasizing the need for densely sampled gold-standard segmentations across early life. This dataset provides a benchmark for evaluating and improving pipelines dependent upon segmentations in the youngest populations. As such, this dataset provides a vitally needed foundation for early-life large-scale studies such as HBCD.

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• dkNET
• 10 months ago - submitted by Maryann Martone

The Cystic Fibrosis Foundation has built a dynamic pipeline for the development of more new potential cystic fibrosis (CF) therapies than ever before. To treat a complex disease like CF, therapies must target problems in the airways and the digestive system. In the CF drug development pipeline, there also are promising new therapies designed to rectify the cause of CF a faulty gene and/or its faulty protein product. Cystic fibrosis is an inherited chronic disease that affects the lungs and digestive system of about 30,000 children and adults in the United States (70,000 worldwide). A defective gene and its protein product cause the body to produce unusually thick, sticky mucus that: clogs the lungs and leads to life-threatening lung infections; and obstructs the pancreas and stops natural enzymes from helping the body break down and absorb food. In the 1950s, few children with cystic fibrosis lived to attend elementary school. Today, advances in research and medical treatments have further enhanced and extended life for children and adults with CF. Many people with the disease can now expect to live into their 30s, 40s and beyond.

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• SciCrunch
• 17 years ago - by Anonymous

Pasteur Institute of Lille is an international research institute in Lille, France focused on bettering human health by detecting risk factors in degenerative diseases.

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• SciCrunch
• 13 years ago - submitted by Andrea Stagg

Provides histology services from sample collection to data analysis.Training is available so that research staff understand the process. Contact us before you start your experiment so we can help you integrate histology with any other tissue-dependent assays you intend to perform.

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• SciCrunch
• 9 months ago - submitted by Edyta Vieth

This website is dedicated to the dissemination of information about the European research project FunGenES (Functional Genomics in Embryonic Stem Cells). FunGenES is a research programme carried out on mouse embryonic stem cells with the aim to improve our understanding of cellular self-renewal and differentiation processes into tissue-specific cells. The website contains general knowledge about stem cell research and related issues such as ethics in stem cell related research, and more detailed information about the specific scope and objectives of the FunGenES project. A brochure containing a general project description in PDF format is available for download in the section Publications. FunGenES - Functional Genomics in Embryonic Stem Cells brings together experts in stem cell research from 18 organisations from industry and academic research across Europe. This research initiative is set up as an Integrated Project with a budget of approximately 12 Million Euros, partially funded by the 6th Framework Programme of the European Union. Specialists from Germany, France, Italy, Portugal, Greece and the UK collaborate for a period of 3 years to investigate the functional genomics of mouse embryonic stem (ES) cells. FunGenES aims to achieve a detailed basic understanding of stem cell self-renewal and differentiation. FunGenES investigates the unique ability of mouse embryonic stem cells to develop into any cell of an organ (this ability is also known as pluripotency), creates new tools for functional genomic studies and will thus provide key knowledge to understand the commitment of cells to a particular cell type. This complex process occurs in several steps and controls the development of pluripotent cells into highly specialised cells of an organism. In particular, FunGenES aims to identify genes controlling the development of the pluripotent ES cells into heart cells (cardiomyocytes), nerve cells (neurons), smooth muscle cells, vascular endothelial cells, fat cells (adipocytes), liver cells (hepatocytes) and insulin-producing cells of the pancreas. FunGenES will deliver a gene expression atlas summarising the genetical pathways for cell differentiation. The project aims to contribute to future therapeutic strategies for degenerative diseases such as heart disease, diabetes and Parkinson''s. All these diseases are characterised by the irreversible loss of functional cells. FunGenES was selected from a large number of proposals to be funded as an advanced and promising project in the area of functional genomics in the Life-Science-Health Programme of the European Union. In addition to its ambitious scientific programme, FunGenES aims to inform the general public about stem cell research, its ethical aspects and future therapeutical applications The project is coordinated by Professor Jrgen Hescheler (University of Cologne) Jrgen Hescheler is excited about the potential of the project: By understanding how mammalian genomic information is selectively used in development, we will acquire an essential key to understanding ourselves and our health. Sponsor. The FunGenES Integrated Project was funded by a grant from the European Commission (6th Framework Programme, Thematic Priority: Life sciences, Genomics and Biotechnology for Health, Contract No. : FunGenES LSHG-CT-2003-503494; http://ec.europa.eu/grants/index_en.htm). H.B. and M.T. were also supported by the University Bordeaux 2 (http://www.u-bordeaux2.fr/index.jsp) and CNRS (http://www.cnrs.fr/); A.K.H. received NIH support, grant HL08395 (http://www.nih.gov/). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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• SciCrunch
• 17 years ago - by Anonymous

Max Planck Institute of Molecular Physiology is located in Dortmund, next to the Dortmund University of Technology. It is one of 80 institutes in the Max Planck Society.

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• SciCrunch
• 16 years ago - submitted by Andrea Stagg

Molecular Pharmacology and Chemical Biology Shared Resource (MPCBSR) provides services for the assessment of new therapeutics, including clinical trial specimens and determination of clinical PK/PD and potential drug-drug interactions (DDI), pharmacological studies on novel therapeutics in preclinical models, including DM/PK/PD, on-target mechanisms, biomarkers, and combination effects, and chemical synthesis of new compounds and drug delivery nanomaterials for improved therapy.

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• SciCrunch
• 9 months ago - submitted by Edyta Vieth

Purpose of the Myc Hubsite The emergence of complex DNA microarray data on gene expression creates vast new opportunities but also poses serious challenges for information and library sciences. This complexity becomes more challenging as certain genes, such as MYC that encodes a transcription factor, switch on other genes. The purpose of this website is to provide a hub for the integration of information on Myc target genes, the role of Myc in human cancers, and proteins that interact with the Myc transcription factors. Links are provided that connect to PUBMED citations, Unigene database, and in specific cases to original data. Sponsor: Funded by a grant from the National Library of Medicine

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• SciCrunch
• 17 years ago - by Anonymous

The United States federal government Department of Education, which oversees policies on federal financial aid for education, collecting data and disseminating research, and working to promote key educational discussions and equal access to education.

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• SciCrunch
• 16 years ago - submitted by Andrea Stagg

Core provides histological services in order to facilitate productivity and success of investigators based in the Rangos Research Center and researchers in other units of the University of Pittsburgh and UPMC, as well as clients in other academic institutions in the Pittsburgh area.

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• RRID
• 8 months ago - submitted by Riley Gedrys

THIS RESOURCE IS NO LONGER IN SERVICE. Documented August 23, 2017.

Annotated database of fluorescence microscope images depicting subcellular location proteins with two interfaces: a text and image content search interface, and a graphical interface for exploring location patterns grouped into Subcellular Location Trees. The annotations in PSLID provide a description of sample preparation and fluorescence microscope imaging.

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• SciCrunch
• 17 years ago - by Anonymous

Commissioned Corps of the United States Public Health Service, is the federal uniformed service of the U.S. Public Health Service, and is one of the eight uniformed services of the United States.

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• SciCrunch
• 17 years ago - submitted by Andrea Stagg

Core provides immunopathological services from sample embedding and staining to microscopic evaluation. Full service for histopathology includes tissue embedding, staining of tissue sections and microscopic analysis: preparation of paraffin blocks,cutting of cryo and paraffin sections,histochemistry,immunohistochemistry/-fluorescence/multiplexing, in-situ hybridization,Scoring/quantification,storage.

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• RRID
• 8 months ago - submitted by Edyta Vieth

Non profit organization and informational portal directed towards patients and families. AFA is an umbrella orgnization uniting over 1600 member organizations to collaborate on education, resources, best practices and advocacy. AFA provides several grant opportunities for AFA's nonprofit member organizations and to individuals in need.

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• SciCrunch
• 16 years ago - by Anonymous

The Danish Multiple Sclerosis Center (DMSC) comprises the MS Clinic and the MS Research Unit including the Neuroimmunology Laboratory. The main research areas are: clinical research including investigator driven trials of new therapies in MS, neuroimaging, neuropsychology and rehabilitation; pathogenesis of MS with focus on immunology, biomarkers and treatment response; as well as studies in the pathology and genetics of MS. DMSC is part of the Department of Neurology, Rigshospitalet, and the Faculty of Medicine, University of Copenhagen. The research facilities are located in sections 6311 and 9392 at the hospital site. DMSC constitutes one of the European MS Centers of Excellence and has extensive collaboration with institutions in Denmark, in other European countries, as well as overseas. DMSC is supported by both national and international grants.

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• SciCrunch
• 16 years ago - by Anonymous