We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Database for completely identified inorganic crystal structures. Collection of known inorganic crystal structures published since 1913, including their atomic coordinates. Includes only data which have passed thorough quality checks. Tool for materials research.
THIS RESOURCE IS NO LONGER IN SERVICE, documented September 2, 2016. SysZNF is an information resource for C2H2 Zinc Finger genes in humans and mice. C2H2 Zinc Finger genes (C2H2-ZNF) constitute the largest class of transcription factors in humans and mouse. C2H2 zinc finger proteins primarily bind to DNA. In most cases, they attach to regions near certain genes and turn the genes on and off as needed. The researches on these genes show light on the evolution of gene regulation systems and development. Therefore, we develop SysZNF (Systematical information resource of Zinc Finger genes) to collect the information related to C2H2 Zinc Finger genes. The aim of SysZNF was to provide a user-friendly interface for rendering the information (DNA, Expression, Protein, Reference and so on) of each C2H2-ZNF (e.g., ZNF10) and to enable a comprehensive analysis of C2H2-ZNF. This project was supported by the Proteome-Center at Rostock University (PCRU) who conceives the concept of the database and Key laboratory of Systems biology at the Shanghai Institute for Biological Sciences (SIBS) who implemented the database. It is maintained jointly by PCRU and SIBS.
Research university in Dublin, Ireland, and a member institution of the National University of Ireland.
Core to promote translation of basic science discoveries by Cleveland Clinic researchers into new therapeutics. Through collaboration with investigators we de-risk promising approaches and illuminate fundamental biology using small molecule chemical probes. We have established a pipeline of innovative research programs directed toward improving patient care with a true bench-to-bedside vision. To achieve these goals, we use state of the art technologies in small molecule library screening, fragment-based methods, X-ray crystallography, computational tools, and target validation towards generating starting points for nascent hit-to-lead and lead optimization campaigns.
Sixty years of study have made Escherichia coli K-12 the most deeply understood organism at the molecular level. Much of what we know about cellular processes can be traced to fundamental discoveries in E. coli. In spite of its great importance as a model organism, information about E. coli is distributed among many online resources. EcoliHub uses web services that are being developed to make seamless bidirectional connections between E. coli resources, thereby enabling the full use of existing knowledge and supporting cutting-edge research into the molecular basis of life. :topical portal;
Public research university in Conway, Arkansas that offers degree programs in nursing, education, physical therapy, business, performing arts, and psychology.
ARGE Research Services is dedicated to empowering Purdue Agriculture research by providing expert solutions in conducting team science, implementing best practices for data acquisition, stewardship, and analysis.
Biopython is a set of freely available tools for biological computation written in Python by an international team of developers. It is a distributed collaborative effort to develop Python libraries and applications which address the needs of current and future work in bioinformatics. The source code is made available under the Biopython License, which is extremely liberal and compatible with almost every license in the world. It works along with the Open Bioinformatics Foundation, who generously host it''s website, bug tracker, and mailing lists. Sponsor: This resource is supported by the Open Bioinformatics Foundation. Keywords: Tool, Software, Python, Biological, Computation, Bioinformatics,
University
University of Ottawa often referred to as uOttawa or U of O, is a bilingual public research university in Ottawa, Ontario, Canada.
Frontiers community is a web portal for both open access Frontiers journals and a community portal for jobs, books, and scholarly events. Frontiers is more than just an open-access publisher of scholarly articles: it is a pioneering approach to the world of academia, radically improving the way scholarly research is managed. The grand vision of Frontiers is a world where all people have an equal opportunity of seeking, sharing and generating knowledge. As a first active measure in this direction, Frontiers provides immediate and permanent online open access to all of its publications, but this alone is not enough to realize our grand goals. The Frontiers solution develops around two main concepts, mutually integrating each other within the innovative Frontiers'' platform: * the Frontiers Journal Series, and * the Frontiers Community. As an open-access Journal Series, Frontiers revolutionizes research publishing by freely delivering the most outstanding research, evaluated with no bias from both the academic and social point of view. As an interdisciplinary Community system, Frontiers is reshaping research management with a state-of-the-art platform, designed as a collaborative architecture and aimed at all research communities, whether academicians or research enthusiasts, investors or grantmakers. By applying the most advanced information technologies, Frontiers is catapulting scholarly publishing into a new 21st century generation.
Public university located in Johannesburg, South Africa. Came into existence on 1 January 2005 as result of merger between Rand Afrikaans University, Technikon Witwatersrand and Soweto and East Rand campuses of Vista University.
Core is fee-for-service research laboratory providing internal and external users a wide spectrum of electron microscopy (EM) techniques. As part of the Houston Methodist Research Institute Department of Neurology, we routinely process samples related to the peripheral nervous system but can help with the ultrastructural study of many biological samples.
Online access (html or xml) to structural connectivity ("wiring") data on the Macaque brain. The database has become by far the largest of its kind, with data extracted from more than four hundred published tracing studies. The main database, contains data from tracing studies on anatomical connectivity in the macaque cerebral cortex. Also available are a variety of tools including a graphical simulation workbench, map displays and the CoCoMac-Paxinos-3D viewer. Submissions are welcome. To overcome the problem of divergent brain maps ORT (Objective Relational Transformation) was developed, an algorithmic method to convert data in a coordinate- independent way based on logical relations between areas in different brain maps. CoCoMac data is used to analyze the organization of the cerebral cortex, and to establish its structure- function relationships. This includes multi-variate statistics and computer simulation of models that take into account the real anatomy of the primate cerebral cortex. This site * Provides full, scriptable open access to the data in CoCoMac (you must adhere to the citation policy) * Powers the graphical interface to CoCoMac provided by the Scalable Brain Atlas * Sports an extensive search/browse wizard, which automatically constructs complex search queries and lets you further explore the database from the results page. * Allows you to get your hands dirty, by using the custom SQL query service. * Displays connectivity data in tabular form, through the axonal projections service. CoCoMac 2 was initiated at the Donders Institute for Brain, Cognition and Behaviour, and is currently supported by the German neuroinformatics node and the Computational and Systems Neuroscience group at the Juelich research institute.
Public university based in the city of Liverpool, England. Founded as a college in 1881, it gained its Royal Charter in 1903 with the ability to award degrees and is also known to be one of the six original 'red brick' civic universities.
Procures high-quality biologic specimens along with coded clinical and demographic data across broad ethnic, racial, and social demographic of patients. All specimens are systematically collected and processed so that their multi-functional potential for recovering high-quality bioanalytes (including RNA, genomic DNA, protein, enzymes and metabolites) is conserved. All specimens are stored and protected in a database hub to connect researchers conducting variety of scientific projects across multiple medical specialties. Muilti-disciplinary biorepository with capacity for generating specialized bioanalytes.
Collects, stores, and distributes samples of nervous tissue, cerebrospinal fluid, blood, and other tissue from HIV-infected individuals. The NNTC mission is to bolster research on the effects of HIV infection on human brain by providing high-quality, well-characterized tissue samples from patients who died with HIV, and for whom comprehensive neuromedical and neuropsychiatric data were gathered antemortem. Researchers can request tissues from patients who have been characterized by: * degree of neurobehavioral impairment * neurological and other clinical diagnoses * history of drug use * antiretroviral treatments * blood and CSF viral load * neuropathological diagnosis The NNTC encourages external researchers to submit tissue requests for ancillary studies. The Specimen Query Tool is a web-based utility that allows researchers to quickly sort and identify appropriate NNTC specimens to support their research projects. The results generated by the tool reflect the inventory at a previous time. Actual availability at the local repositories may vary as specimens are added or distributed to other investigators.
Public research university in Oxford, Mississippi. Including the University of Mississippi Medical Center in Jackson, it is the state's largest university by enrollment and promotes itself as the state’s flagship university.
Core is dedicated to providing access to cost-effective and high quality genomics services including standard and custom-tailored DNA sequencing using Illumina technologies, epigenomics, panel-based profiling (Luminex and Nanostring) and functional genomics. Single cell genomics applications on variety of popular platforms.
The UCSD-Nature Signaling Gateway Molecule Pages provide essential information on more than 3900 proteins involved in cellular signaling. Each Molecule Page contains regularly updated information derived from public data sources as well as sequence analysis, references and links to other databases. Published Molecule Pages contain an expert-authored review article that describes the biological activity, regulation and localization of the protein. This review is supplemented by highly structured data that illustrate protein-protein interactions, post-translational modifications, subcellular localization and biological function. :Prior to publication, Nature Publishing Group administers rigorous peer and editorial review of each Molecule Page. The published pages are citable by digital object identifiers (DOIs). All data in the Molecule Pages are freely available to the public. :proteins, cellular signaling, neurobiology, genetic and structural information, biophysical properties, 5-Hydroxytryptamine receptor 2A, 5-Hydroxytryptamine receptor 2B, 5-Hydroxytryptamine Receptor 6, Adrenergic receptor a1a, Adrenergic Receptor 1, Ags1, Ags3, Arg, Darpp32, DCLK1, Dopamine receptor D3, Galanin receptor 1, Galanin receptor 2, (Glutamate receptor, metabotropic, type 1), (Glutamate receptor, metabotropic, type 5), (Glutamate receptor, metabotropic, type 8), Homer 1a, Homer 1b, Homer 1c, Homer 2a, Homer 2b, Homer 3, Laminin 2, Mark1, Mlk3, Neurotensin receptor 1, Neurotensin receptor 2, Trpc3, Trpc6, Trpc7, Trpm1, Trpm3, Trpm6, Trpv4, sequence analysis, protein-protein interactions, post-translational modifications, subcellular localization, biological function, signaling molecules, transcription factors, membrane receptors, Lcmt2, HB-EGF, Pak1, Itpk1, Ubr5, Rab35, CAP1, Plasma membrane calcium transporting ATPase isoform 4, 5-Hydroxytryptamine receptor 2C, Vangl2, mTOR, Catenin, beta, Pak1, Ubr5, Adrenergic receptor alpha 2a, Plasma membrane calcium transporting ATPase isoform 4, PCAF lysine acetyltransferase, G protein alpha 13, Rab35, Cell signaling, molecules, signaling protein, protein-protein interactions, subcellular localizations, post-translational modifications, enzymatic functions, states (A state is a physiological condition of a molecule), functions, transitions, network map, protein class, protein function, regulation of activity, interactions with ligands and other proteins, regulation of concentration (both protein and mRNA), subcellular localization, major sites of expression, phenotypes, splice variants and antibodies, pathways, Domains and Motifs, Orthologs and Blast Data,