Curator Dashboard

Services include genome editing of mice, rats and cell lines, mouse line cryopreservation and re-derivation, ES cell targeting, PDX models, drug screening.Crispr Mediated KO/KI and Conditional KO Mice,KI mouse by mouse ES cell genome editing,Integrase Mediated Transgenesis,Conventional Transgenic Mouse,Mouse Line Services,Cell Line Services. Tumor Model Services include In vivo tumor models,In vivo pharmacology,In vitro and biochemical assays,Translational imaging services.

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• SciCrunch
• 3 years ago - submitted by Edyta Vieth

A brain imaging classification tool, which can help researchers to discriminate patients from normal controls. The M3 includes three steps: feature selection, maximum uncertainty linear discriminant analysis (MLDA)-based classification and multi-classifier. A leave-one-out cross-validation (LOOCV) is further used to estimate the performance of the M3. Finally, the most discriminative features are identified.

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• SciCrunch
• 13 years ago - by Anonymous

Core that supports and coordinates the NORCH and all the components of the center. It provides insight into the processes that govern the center, to recruit and vet new members, and to communicate with all our members about center happenings.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Provides access to highly specialized and custom genomics and epigenomics assays that Genomics Core Facility does not currently support. Examples include ATAC sequencing; RUN sequencing;Tag sequencing;Chromatin immunoprecipitation;Custom assays. Offers hands-on experiences and training for researchers in genomic technologies, methodologies, and instrumentation.

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• SciCrunch
• 3 years ago - submitted by Craig Praul

Software tool to detect physiologic signals from the data itself as well as an adaptive physiologic noise removal tool (Impulse Response Function or IRF-RETROICOR) that zooms in on noise with only 6 regressors, getting all the noise that 5th order RETROICOR gets. These tools will allow you to correct your data for physiologic noise with what you currently have. These signals are equivalent to a parallel monitored pulse signal and a respiratory chest-bellows signal. Do you have 3D+time EPI data (BOLD or perfusion) but no usable physio signals for pulse and respiration? Are you concerned about the effect of physio noise on your data but don't know what to do but regress data-derived signals that mix unknown functional signal with possible physio noise signal? Are you concerned about the number of regressors you're incorporating once you add 5th order RETROICOR (20 more regressors!)? This is for you.

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• SciCrunch
• 13 years ago - by Anonymous

Software that analyzes and estimates heritability. LDAK adjusts for linkage disequilibrium (LD) by calculating SNP weightings which downweight the contribution of SNPs in highly tagged regions.

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• RRID-Legacy
• 10 years ago - by Anonymous

Open source, and interactive platform to resolve trans disciplinary problems related to coastal and marine ecosystem. Data sharing and science communication portal holds amounts of fishery, reef, and mangrove data pertaining to Gulf of California and Mexico specific oceans, and delivers this information in interactive and easily digestible manner. Consistently expands library of datasets while improving functionality and overall usability of the platform. Facilitate access to scientific knowledge and data to promote transparency, education, and deeper understanding of Mexico’s ecosystems and their biodiversity to bridge gap between science and design process of conservation and resource management programs.

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• RRID
• 3 years ago - submitted by Edyta Vieth

An MRI-based atlas of normal adult human brain anatomy, generated by template-free nonrigid registration from images of 24 normal control subjects. The atlas comprises T1, T2, and PD weighted structural MRI, tissue probability maps (GM, WM, CSF), maximum-likelihood tissue segmentation, DTI-based measures (FA, MD, longitudinal and transversal diffusivity), and two labels maps of cortical regions and subcortical structures. The atlas is provided at 1mm isotropic image resolution in Analyze, NIFTI, and Nrrd format. We are also providing an experimental packaging for use with SPM8.

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• SciCrunch
• 13 years ago - by Anonymous

De novo sequence assembler that can reconstruct genomic sequences of highly heterozygous diploids from massively parallel shotgun sequencing data., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 10 years ago - by Anonymous

Synthesis science center to help to transform ecology and environmental science to generate bigger insights. Leader in environmental data science, has led development of technological solutions to improve data access and management and efficiency of analyses, and helped set scientific standards in data ethics.

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• RRID
• 3 years ago - submitted by Edyta Vieth

Software framework which uses an unscented Kalman filter for performing tractography. At each point on the fiber the most consistent direction is found as a mixture of previous estimates and of the local model. It is very easy to expand the framework and to implement new fiber representations for it. Currently it is possible to tract fibers using two different 1-, 2-, or 3-tensor methods. Both methods use a mixture of Gaussian tensors. One limits the diffusion ellipsoids to a cylindrical shape (the second and third eigenvalue are assumed to be identical) and the other one uses a full tensor representation. The project is written in C++. It could be used both as a Slicer3 module and as a standalone commandline application.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides Center investigators and their laboratories the tools and advice needed to establish and study mouse (including transgenic and knockout) and human (i.e. GI organoids) physiology of GI disease.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

THIS RESOURCE IS NO LONGER AVAILABLE. SAME SERVICES ARE AVAILABLE IN Molecular Virology and Sequencing Core. Documented on January 28,2025. Core provides services for maintaining Specific Pathogen Free status in macaque breeding colonies. Services include antibody detection in serum or plasma by Luminex-based assays and /or ELISA for SPF-agents like SIV, SRV, STLV, B virus, SFV. CMV, RRV, SVV, SV40, and LCV, and non-SPF infectious agents like measles, Burkholderia pseudomallei, Tripanosoma cruzi, Mycobacterium tuberculosis, and SARS-CoV-2. Offers services of cytokines quantification, and molecular assays for detection of SRV, CMV, SFV, and RRV.Performs nucleic acid purification from blood and tissue samples as well as qPRC for SIV viral load in plasma, cells, or tissue.

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• SciCrunch
• 3 years ago - submitted by Edyta Vieth

A stand-alone axecutable under all main Windows OS for training the working memory. The WM Trainer looks and behaves a little bit like a video-game and has been specifically conceived for children attending the primary school. However, it can be used purposefully by people of any age, including adult and elderly. This application features highest graphic quality, a powerful adaptive engine for the difficulty level, a database of users and statistical tools to evaluate the progress. Currently English, French and Italian are supported, but any language can be easily supported.

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• SciCrunch
• 13 years ago - by Anonymous

Search engine for querying novel microbiome samples against a comprehensive database of curated samples. Visibiome accepts rRNA data in the form of BIOM files.

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• RRID-Legacy
• 9 years ago - by Anonymous

Medical Genome Facility includes Cytogenetics Core, Genome Analysis Core and Proteomics Core. Available services include Sanger DNA sequencing, genotyping, gene expression and cytogenetic analysis, biospecimens accessioning and processing, tissue and cell molecular analysis, RNA interference, and oligonucleotide synthesis. Provides Illumina HiSeq2000 platforms and Pacific Biosciences RS single molecule real-time sequencer.Offers applied research services for development of innovative, personalized tests and treatments, especially with regard to biomarkers.

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• SciCrunch
• 3 years ago - submitted by Edyta Vieth

A Semantic content editor based on TinyMCE WYSIWYG editor. RDFaCE is created as a proof of concept for WYSIWYM (What You See Is What You Mean) concept. WYSIWYM aims to enable end-users to easily annotate their content using RDFa and Microdata markups. RDFaCE employs external NLP APIs to suggest namespaces, properties, URIs and to automatically annotate content.

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• SciCrunch
• 13 years ago - by Anonymous

Database that integrates evidence on tissue expression from manually curated literature, proteomics and transcriptomics screens, and automatic text mining. It maps all evidence to common protein identifiers and Brenda Tissue Ontology terms, and further unifies it by assigning confidence scores that facilitate comparison of the different types and sources of evidence.

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• SciCrunch
• 9 years ago - submitted by Daniel Himmelstein

Biomedical technology research center that focuses on the computational bottlenecks that impair the interpretation of data, bringing modern algorithmic approaches to mass spectrometry and building a new generation of reliable, open-access software tools to support both new mass spectrometry instrumentation and emerging applications.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 17,2023. A database of genes and interventions connected with aging phenotypes including those with respect to their effects on life-span or age-related neurological diseases. Information includes: organism, aging phenotype, allele type, strain, gene function, phenotypes, mutant, and homologs. If you know of published data (or your own unpublished data that you'd like to share) not currently in the database, please use the Submit a Gene/Intervention link.

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• SciCrunch
• 14 years ago - by Anonymous