We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Software R package to integrate and query microRNA (miRNA) data. It allows retrieve and analyze validated and predicted miRNA-target interactions, as well as their associations with various diseases and drugs.
Ontology in the domain of role classification that aims to standardize role classification and support computer-assisted reasoning. RoleO is a community-based ontology, and its development follows the OBO Foundry principles.
Comprises six service groups. Our services are available to all NIH intramural researchers, and by interagency agreements to FDA and US Army at Ft. Detrick. We are happy to consult and distribute materials to not-for-profit institutions.Clone Optimization service include DNA cloning for protein expression; Gateway-based; fluorescent, epitope, solubility, purification tags; mutagenesis; vectors for insect/ baculovirus, mammalian, E. coli, P. pastoris, K. lactis. Microbial Expression: E. coli, P. pastoris, K. lactis, 2 mL to 60 L, autoinduction and IPTG; fully instrumented fermenters.Eukaryotic Expression service include insect / baculovirus, mammalian transient and stable, monoclonal antibodies.Protein Purification service include parallel microscale for process development; affinity and native, tag and endotoxin removal; scale-up to low gram scale.Virus Technology service include custom and stock adenovirus and lentivirus production; titer determination; promoter and reporter panels in lentivirus ready to deliver.Molecular Detection: qPCR and ELISA assaysdeveloped and executed, focused on human viruses in human samples; qPCR assays for mycoplasma and human pathogenic viruses contaminating cell lines; cell line identity testing.
Core offers nanofabrication services and tools for lithography, deposition, etch, and characterization. Used for researching, building, and measuring materials on a microscopic scale. Provides cleanroom space and advanced tools for academic and industry projects.
Ontology of the value set for the Other Factors property of the International Classification of Traditional Medicine (ICTM).
Web tool as official query tool for Wikidata.
Software analysis pipeline for CUT&RUN and CUT&TAG experiments that includes QC, support for spike-ins, IgG controls, peak calling and downstream analysis. Used to process and analyze CUT&RUN, CUT&Tag, and TIP-seq genomic data. It maps protein-DNA interactions and chromatin profiles (similar to ChIP-seq, but with lower background noise) in a reproducible, portable way.
Ontology for pseudogenes including biological feature, classified type, Evidence code, and subcellular origin.
Software R package to identify cells with active gene sets in single cell RNA-seq data. Used for analysis of gene set activity in single cell RNA-seq data.Used to calculate whether critical subset of input gene set is enriched within expressed genes for each cell.
Core develops and utilizes preclinical and in-vivo systems for the testing of novel cancer therapeutics. Provides technical services and collaboration with the IACUC, DCM, and other core facilities on campus for labs that utilize small laboratory animals in their research. Offers technical expertise with small laboratory animal models for reproducibility of research at UNC, and complete study management as well as individual services. Technicians are experienced, highly skilled, and maintain American Association for Laboratory Animal Science Technician/Technologist (AALAS) certifications.
Software toolbox for data processing and analysis of brain imaging, evolved from DPARSF (Data Processing Assistant for Resting-State fMRI).
Software tool as macro for SPSS, SAS, and R that conducts observed variable mediation, moderation, and conditional process analysis.Observed variable OLS and logistic regression path analysis modeling tool. Used for estimating direct and indirect effects in single and multiple mediator models parallel and serial, two and three way interactions in moderation models along with simple slopes and regions of significance for probing interactions, and conditional indirect effects in moderated mediation models with single or multiple mediators or moderators. Operates on Windows and Mac versions of SPSS and SAS.
Software R package for the statistical identification and removal of contaminant sequences in marker-gene (e.g. 16S rRNA) and metagenomics sequencing data. Implements frequency- and prevalence-based contaminant identification methods. Used for simple statistical identification and removal of contaminants in marker-gene and metagenomics sequencing data.
Not for profit, precompetitive alliance of life science companies, vendors, publishers, and academic groups that aims to lower barriers to innovation by improving interoperability of R and D business processes.
Atlas is set of interactive tools built to promote retrieval, exploration, discovery, and analysis of Kidney Precision Medicine Project data by greater research community. Datasets available in repository are combination of raw and processed data from KPMP participant biopsies and reference tissue samples.
Academic health science center, located in the city of Jackson. Health sciences campus for the University of Mississippi. UMMC trains future medical professionals. It has multiple health science schools.
Genetic Alliance Registry and BioBank is a centralized, clinical data registry and sample repository (including DNA, serum, cells and tissues) that enables translational research. It is a nonprofit organization established by seven patient advocacy organizations. These organizations share resources for their BioBanks, such as the contract to the independent lab that processes the samples, but each organization will maintain ownership, control and costs associated with their sample collection. Founded in 2003, this cooperative venture provides shared infrastructure and customized solutions for disease advocacy organizations to lead sophisticated research initiatives. Genetic Alliance Registry and BioBank is an advocacy owned repository for biological samples and clinical data. It provides: * Centralized, standardized collection and archiving * Highest biorepository and participant protection standards * Open access for all organization approved researchers * Advocacy organization control
Software pipeline for creating harmonized single cell RNA-seq dataset for retina with publicly available data. Platform for analysis of single cell eye in disk. Snakefile based process to turn 1.4 million ocular cells into unified meta-atlas. Meta-atlas that compiles 1.2 million single-cell back of the eye transcriptomes across studies, publications, and species.
Core supports basic and translational cancer research by providing access to instrumentation and software for quantitative, multi-scale, and multi-modal fluorescence imaging. Provides access to commercial instruments for fluorescence, phase, or brightfield imaging, as well as multiple software platforms for image analysis.
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016.