Curator Dashboard

Database of traceable, standardized, annotated gene signatures which have been manually curated from publications that are indexed in PubMed. The Advanced Gene Search will perform a One-tailed Fisher Exact Test (which is equivalent to Hypergeometric Distribution) to test if your gene list is over-represented in any gene signature in GeneSigDB. Gene expression studies typically result in a list of genes (gene signature) which reflect the many biological pathways that are concurrently active. We have created a Gene Signature Data Base (GeneSigDB) of published gene expression signatures or gene sets which we have manually extracted from published literature. GeneSigDB was creating following a thorough search of PubMed using defined set of cancer gene signature search terms. We would be delighted to accept or update your gene signature. Please fill out the form as best you can. We will contact you when we get it and will be happy to work with you to ensure we accurately report your signature. GeneSigDB is capable of providing its functionality through a Java RESTful web service.

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• SciCrunch
• 15 years ago - by Anonymous

Facility provides full service whole genome and targeted molecular profiling of DNA and RNA on multiple platforms. Core supports quantitative RNA profiling (gene expression) on Affymetrix GeneChips and high-throughput Gene Titan instruments, Fluidigm BioMark HD and, ABI QS 12K real-time PCR machine. DNA profiling (genotyping) is offered on Affymetrix SNP GeneChip and high-throughput Gene Titan instruments, Fluidigm BioMark HD and, ABI QS 12K. Agilent aCGH platform provides genome-wide chromosomal analysis.Users benefit from consultation and training available throughout their projects, including during experimental design and budget development, sample accrual, data management and analyses and, manuscript preparation.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

THIS RESOURCE IS NO LONGER IN SERVCE, documented June, 2019.Comparative Genomic Visualization with Adobe Flash.

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• SciCrunch
• 13 years ago - by Anonymous

Provides comprehensive services essential to the conduct of clinical research projects, including Phase I-IV, multi-center, randomized, clinical trials, registry, and cohort studies. Offers expert staff who maintain a strong focus on data integrity and quality and offers support in optimizing process tracking and management to enhance operational efficiency. Core specializes in the following: Study design and development; Site management and training; Data collection, processing, and quality control; Regulatory requirements and reporting; Database development, storage, and security; System integration (e.g., EPIC data); 21CFR Part 11 Compliance; Proposal development and administration; REDCap development; Honest Broker services.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

A suite of free software tools to facilitate the analysis of high-throughput genomics data sets. The package is currently a work-in-progress and infrequently updated.

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• SciCrunch
• 14 years ago - by Anonymous

Provides histological services, equipment, and technical expertise for processing and analyses of digestive, pancreatic, and liver tissues as well as three dimensional tissue culture models.�Part of the Center for Molecular Studies in Digestive and Liver Diseases

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

The International Behavioral Neuroscience Society (IBNS) was formed to encourage research and education in the field of behavioral neuroscience. Founded in 1992, the IBNS has approximately 719 members which derive from 36 different countries and consist of scientists, clinicians, teachers, and others with a background and interest in the relationship between brain and behavior. :

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• SciCrunch
• 17 years ago - by Anonymous

Offers embryological manipulation services, focused on, but not limited to, murine model systems. These services primarily enable generation of genetically modified murine models, as well as experimental research in germ cell function and early embryonic development.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

It fosters Interdisciplinary research, teaching, and service activities linked to health and development in Nigeria and resource limited settings of the developing world. :OBJECTIVES OF THE CENTRE: The Institute helps strengthen and sustain the interests and activities of the science community by: :Facilitation of international contacts for program development and training. :* Advocacy for better equity in global health investments. :* Assistance in securing resources for international activities. :* Standardization and facilitation of overseas administrative approaches. :* Improved communication through grand rounds, seminars, and discussion forums. :* Taking up public enlightenment campaigns and public health education :* Active partnerships with institutions in Nigeria and abroad that share the Institute''s goals and wish to partner with CSIT faculty, staff, and students. :* Publishes the JEN Biomedicine, an international journal that gives unfettered access to research from Nigeria and other parts of Africa and the world. :* It''s CSIT Service Centre that helps with works and writing of scientists to make them acceptable for publication. The centre is equipped with research aids and staff that can help out with planning, executing, writing, graphic works including black and white and colour photos, editing research papers to make them acceptable by journals of interest. You can also undertake statistical analyses. In particular preparing journal figures, peer-review before publication, and statistical analyses. :* It''s Teaching Aids Centre that provides teaching aids to institutions and for workshops and conferences. Has in store models for studying behaviour including Elevated plus, Y, T, Radial-arm, Light/Dark Box, Open Box mazes. Available also are projectors, image analysers, computers, scanners, microscopes, microscope slides, animal skeletons, fixed animal tissues for biology and anatomy, patch clamping, stereotaxic equipment and methods, etc. The Centre can also teach you how to use any of the above. :

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• SciCrunch
• 14 years ago - by Anonymous

Software R package for mixed models with single variance component besides residual error, which allows for efficient prediction with unreplicated training data. Makes ridge regression and other kernel methods accessible to plant breeders interested in genomic selection.

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• RRID
• 4 years ago - submitted by Muhammad Farooq

Archive that acquires, preserves and disseminates data relevant to drug addiction and HIV research. Collection of data on drug addiction and HIV infection in United States. Most of datasets are raw data from surveys, interviews, and administrative records. They were originally gathered in research projects and for administrative purposes. Some datasets have been used in published studies. Bibliographies of these studies are available . Provides access to research data and technical assistance for data depositors. Provides e-workshops on data preparation and data systems.

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• SciCrunch
• 16 years ago - by Anonymous

Provides access to mass spectrometers and mass spectrometry expertise. The facility currently maintains the following equipment Waters Synapt-XS Q-IMS-TOF with Waters I-Class UHPLC; Agilent 6538 Q-TOF with Agilent 1290 UHPLC;Agilent 7800 Inductively Coupled Plasma with Laser Ablation (193 nm);Bruker micrOTOF with Agilent 1290 UHPLC; Agilent 6490 Triple Quadrupole Mass Spectrometer; Bruker MALDI Autoflex; Agilent GC-MS; Waters Synapt G2S-i Q-TOF with Ion Mobility.

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• SciCrunch
• 14 years ago - by Anonymous

Database developed to archive and distribute clinical data and results from studies that have investigated interaction of genotype and phenotype in humans. Database to archive and distribute results of studies including genome-wide association studies, medical sequencing, molecular diagnostic assays, and association between genotype and non-clinical traits.

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• SciCrunch
• 17 years ago - by Anonymous

Part of AIRR Data Model, describes abstract organizational unit of analysis that is defined by researcher and consists of study metadata, subject metadata, sample metadata, cell processing metadata, nucleic acid processing metadata, sequencing run metadata, set of raw sequence files, data processing metadata, and set of Rearrangements. Repertoire gathers all of this information together into composite object, which can be easily accessed by computer programs for data entry, analysis and visualization. AIRR Repertoire Schema has been implemented in YAML/JSON, which provides mechanism to share AIRR Repertoire metadata between research projects.

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• dkNET
• 4 years ago - submitted by Ko-Wei Lin

Structural variation database designed to store data on variant DNA > / = 1 bp in size from all organisms. Associations of defined variants with phenotype information is also provided. Users can browse data containing number of variant cells from each study, and filter studies by organism, study type, method and genomic variant. Organisms include human, mouse, cattle and several additional animals.

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• SciCrunch
• 13 years ago - by Anonymous

Helps investigators integrate, interpret and explore large and diverse datasets. Provides services that support analysis of large scale datasets for biomedical researchers, drawing on expertise in computational biology, software engineering and cloud architecture. Offers project based scientific analysis by bioinformaticians, automation of analytical pipelines using workflow management platforms, publication of complex datasets with web accelerated graphics, training and documentation to enable scientist driven computation.

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• SciCrunch
• 4 years ago - submitted by Cassie Sather

Collection of information about chemical structures and biological properties of small molecules and siRNA reagents hosted by the National Center for Biotechnology Information (NCBI).

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• SciCrunch
• 16 years ago - by Anonymous

Provides access to advanced analytical imaging and image post-processing methods for collaborators involved in basic and clinical research.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

An atlas of normal and abnormal brain images intended as an introduction to basic neuroanatomy, with emphasis on the pathoanatomy of several leading central nervous system diseases that integrates clinical information with magnetic resonance (MR), x-ray computed tomography (CT), and nuclear medicine images. A range of brain abnormalities are presented including examples of certain brain disease presented with various combinations of image type and imaging frequency. Submissions of concise, exemplary, clinically driven examples of neuroimaging are welcome.

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• SciCrunch
• 15 years ago - by Anonymous

Lab houses three cores providing support and services from nucleic acid isolation through data generation on multiple genomic and molecular analysis platforms. Nucleic acid extraction, qPCR, and Nanostring profiling services are available through the Gene Profiling Shared Resource for gene expression profiling, microRNA profiling, DNA genotyping and copy number analysis, and DNA methylation analyses. Currently running QuantStudio real-time PCR system. Comprehensive RNA and DNA extraction and quality assessment services available. Massively parallel sequencing (NGS) services, including library preparation, are available through Massively Parallel Sequencing Shared Resource on Illumina NovaSeq 6000 and NextSeq platforms. 10x Genomics single-cell and single-nuclei analysis services available. Cell line authentication, DNA plating, and custom oligo services are available through DNA Services Core.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth