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Showing 20 out of 11,605 Resources on page 570

Predictive Safety Testing Consortium

A public-private partnership to identify new and improved translational safety testing methods for use in nonclinical and clinical studies and submit them for formal regulatory qualification by the FDA (Food and Drug Administration), EMA (European Medicines Agency), and PMDA (Japanese Pharmaceutical and Medical Devices Agency). The current 19 corporate members of the consortium share internal experience with nonclinical and clinical safety biomarkers in six working groups: cardiac hypertrophy, nephrotoxicity, hepatotoxicity, skeletal myopathy, testicular toxicity, and vascular injury. The ultimate goal of the consortium is to improve the current approach to drug safety testing and offer assurance to the drug developers that these approaches will be accepted by the regulatory authorities in their drug development programs. Through PSTC, members are able to share their expertise, resources, data, and internally developed approaches in a neutral, precompetitive, confidential environment. There are more than 250 participating scientists and C-Path serves as the trusted third party, leading the collaborative process by collecting and summarizing the data, and leading the interactions with global health authorities.


Apache Spark

Software tool as a unified analytics engine for large scale data processing. An open source distributed general purpose cluster computing framework.

  • Resource
  • RRID-Legacy
  • 8 years ago - submitted by Boaz Mohar

Spectran

Software R package with web based GUI for spectral analysis of light.

  • Resource
  • RRID
  • 2 years ago - submitted by Edyta Vieth

Paleobiology Database

A non-governmental, non-profit public database for paleontological data providing researchers and the public with information about the entire fossil record. It has been organized and operated by a multi-disciplinary, multi-institutional, international group of paleobiological researchers. Its purpose is to provide global, collection-based occurrence and taxonomic data for organisms of all geological ages, as well data services to allow easy access to data for independent development of analytical tools, visualization software, and applications of all types. The Database's broader goal is to encourage and enable data-driven collaborative efforts that address large-scale paleobiological questions. Paleontological data files are accepted for upload. However, PaleoBioDB needs some basic data types to be included in order to perform an upload. The Application Programming Interface (API) gives scientists, students, and developers programmatic access to taxonomic, spatial, and temporal data contained within the database.

  • Resource
  • SciCrunch
  • 13 years ago - by Anonymous

biobakery

Analysis environment and collection of individual software tools to process raw shotgun metagenome or metatranscriptome sequencing data for quantitative microbial community profiling. Used for a metaomics data analysis., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

  • Resource
  • SciCrunch
  • 8 years ago - submitted by Edyta Vieth

Yale School of Medicine Flow Cytometry Core Facility

Core provides comprehensive flow cytometry analysis and cell sorting including instrumentation, technical support, training and consultation.

  • Resource
  • RRID
  • 2 years ago - by Anonymous

Ontology of Physical Exercises

Ontology that provides a reference for describing an exercise in terms of functional movements, engaged musculoskeletal system parts, related equipment or monitoring devices, intended health outcomes, as well as target ailments for which the exercise might be employed as a treatment or preventative measure.

  • Resource
  • SciCrunch
  • 13 years ago - by Anonymous

MouseLight Neuron Browser

Interactive web platform for anyone to explore, search, filter and visualize the single neuron reconstructions.

  • Resource
  • RRID-Legacy
  • 8 years ago - submitted by Anita Bandrowski

University of Virginia School of Medicine Radiochemistry Core Facility

Provides access to high-quality novel and existing radiopharmaceuticals (radiolabeled small molecules, peptides, proteins, and antibodies), that can be imaged by Positron Emission Tomography (PET) method, to meet their preclinical and clinical needs. Radiochemistry core is Good Manufacturing Practices (cGMP) certified facility as required by the U.S. Pharmacopeia Chapter 823 and 21CFR part 212 and is BSL-2 certified facility to conduct research.

  • Resource
  • RRID
  • 2 years ago - submitted by Phillip Deyerle

ONE Study

Consortium aiming to produce regulatory T cells that are compatible with a kidney transplant patient''''s immune system, as a measure to suppress the body''''s natural immune response against a transplanted organ. If successful, this approach will reduce a transplantation patient''''s life-long dependency on immune suppressing drugs, many of which are often associated with undesirable side effects and can limit the patient''''s daily routine. The consortium goals are to develop and conduct clinical trials of various immunoregulatory T-cell-based products in organ transplantation recipients, allowing a direct comparison of the safety, clinical practicality and therapeutic efficacy of each cell type. The central focus of the project is to: # Production and manufacture of distinct populations of hematopoietic immunoregulatory T cells # Comparatively study the tolerogenic characteristics of these regulatory cell types # Test these cell therapy products side by side in a clinical trial living donor renal transplant recipients The first workstream will work with different T regulatory cell, tolerogenic DC and suppressive macrophage cell products that are currently in development. In addition to these therapeutics, another goal of this workstream is to develop a cell tracking technology that assesses pharmacodynamics and pharmacokinetics of these cell-based therapies. The second workstream is focused on designing and conducting a cell therapy based clinical trial in renal transplantation, taking into consideration ethics, concurrent immunosuppressive drug use, state-of-the-art immune monitoring, innovative all-in-one data capturing systems, and pharmacovigilance. The goal is to have a comparative evaluation of hematopoietic cell therapy safety in renal transplantation. The third workstream aims to learn more about the specific comparative characteristics of suppressive cell types and to use this knowledge to improve later trial designs and foster novel ideas for new or improved suppressive / tolerogenic cell population.


Science and Technology Facilities Council

One of nine Councils within United Kingdom Research and Innovation, an organisation that brings together the UK’s Research Councils, Innovate UK and Research England. Works in partnership with universities, research organisations, businesses, charities, and government to create the environment for research and innovation.

  • Organization
  • SciCrunch
  • 8 years ago - submitted by Edyta Vieth

Indiana University School of Medicine Bioinformatics Core Facility

Bioinformatics Core provides advanced computation and informatics approaches to analyze large and complex biological datasets. Core offers services including Next Generation Sequence Data Analysis; Microarray Data Analysis; Proteomics Data Analysis;Multi-omics Data Integration;Statistical Genetics;Pharmacokinetics/Pharmacodynamics Data Analysis; Drug Absorption, Disposition, Metabolism, Elimination and Transportation Prediction, and Drug Exposure Prediction;Public Domain Database Access and Custom Data Annotation.

  • Resource
  • SciCrunch
  • 2 years ago - submitted by Edyta Vieth

American Nephrology Nurses Association

Non-profit professional association that represents nurses who work in all areas of nephrology including hemodialysis, chronic kidney disease, peritoneal dialysis, acute care, and transplantation. Most members work in freestanding dialysis units, hospital outpatient units, and hospital inpatient units. ANNA develops and updates standards of clinical practice, educates practitioners, stimulates and supports research, disseminates knowledge and new ideas, promotes interdisciplinary communication and cooperation, and monitors and addresses issues encompassing the breadth of practice of nephrology nursing.

  • Resource
  • SciCrunch
  • 12 years ago - by Anonymous

Leginon

System designed for automated collection of images from a transmission electron microscope.

  • Resource
  • SciCrunch
  • 8 years ago - submitted by Edyta Vieth

km.ci

Software R package to compute various confidence intervals for the Kaplan-Meier estimator, namely: Peto's CI, Rothman CI, CI's based on Greenwood's variance, Thomas and Grunkemeier CI and the simultaneous confidence bands by Nair and Hall and Wellner.

  • Resource
  • RRID
  • 2 years ago - by Anonymous

ACTTION

A public-private partnership with the United States Food and Drug Administration (FDA) to identify, prioritize, sponsor, coordinate, and promote innovative activities - with a special interest in optimizing clinical trials - that will expedite the discovery and development of improved analgesic, anesthetic, and addiction medications and to more generally accelerate the development of treatments with improved efficacy and safety. This multi-year, multi-phase initiative is closely aligned with the FDA''''s Critical Path Initiative. The key objectives of ACTTION involve initiating and supporting strategic collaborations among a broad spectrum of stakeholders - including, but not limited to, academia, the FDA and other government agencies, industry, professional organizations, patient advocacy groups, foundations, and philanthropic organizations - with the goals of sharing data and innovative thinking about the development of novel therapeutics. These strategic collaborations involve a wide range of research projects and other activities, for example, scientific workshops, consensus meetings, and in-depth analyses of clinical trial data to determine the effects of research methods on study assay sensitivity and efficiency. ACTTION launched an initiative to develop training materials for clinical trial subjects (and staff) to be used with pain rating scales and other pain-related patient reported outcomes. Once materials have been developed and evaluated, proof-of-concept trials will be conducted to test the hypothesis that patient and staff training can improve the assay sensitivity of analgesic trials.


Juventus Inter in DIRETTA STREAMING

Juventus Inter in DIRETTA STREAMING

  • Resource
  • SciCrunch
  • 8 years ago - submitted by Juve Inter Calcio In tv Streaming

Peter MacCallum Cancer Centre Research Flow Core Facility

Internationally recognised shared resource laboratory which provides researchers with access to equipment, education and expertise that enables isolation, separation and analysis of cell populations.

  • Resource
  • RRID
  • 2 years ago - by Anonymous

Renal Support Network

A nonprofit, patient-focused, patient-run organization that provides non-medical services to those affected by chronic kidney disease (CKD). RSN strives to help patients develop their personal coping skills, special talents, and employability by educating and empowering them and their family members to take control of the course and management of the disease. RSN plays a vital role in providing lawmakers and policymakers with the patient''s perspective on the needs and capabilities of people with CKD.

  • Resource
  • SciCrunch
  • 12 years ago - by Anonymous

AD Model Builder

Open source software suite environment for nonlinear statistical modeling enabling model development, numerical stability, computation, and accuracy parameter estimates. Language built around the AUTODIF Library, a C++ language extension which transparently implements reverse mode automatic differentiation.

  • Resource
  • SciCrunch
  • 8 years ago - submitted by Edyta Vieth