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A database of over 300 Electron Microscopy (EM) images of centrioles and centriole related structures from almost 60 species, described by a controlled vocabulary allowing detailed description of the observed structures. This knowledge is supplemented by a manually curated list of proteins known to be involved in centriole assembly, their (putative) orthologs, and localization information. mtocDB aims to characterize the naturally occurring morphological variation observed in centrioles and centriole associated structure alongside molecular information on the proteins involved in their assembly. Examining these in an evolutionary context will allow the cell biology community to infer meaningful relationships between cellular assembly mechanisms and the structures they form. This community resource for cell biologists interested in the the evolution of centrioles and centriole related structures aims to bridge the gap between structural morphology and molecular function by examining naturally occurring structural variation in a phylogenomic context. Centrioles are cylindrical microtubule arrays required for stability and duplication of the centrosome in animal cells, and for the assembly of cilia and flagella in many eukaryotes. The presence of centrioles throughout most eukaryotic branches suggests that this structure was present in the last eukaryotic common ancestor. Although centrioles show a typically well conserved structure, they can perform several functions and display a diversity of accessory structures. However, this diversity is not properly classified beyond model organisms, and the information contained in decades of electronic microscopy of other organisms remains untapped.

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• SciCrunch
• 14 years ago - by Anonymous

Commercial supplier of bioproducts for studies of inflammation, autoimmune disease, cancer, coronary disease, Alzheimer's Disease and more. These include antibodies, enzymes, coagulation factors, and assay kits.

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• SciCrunch
• 14 years ago - by Anonymous

Ethiopia's oldest and largest public research university, founded in 1950 and located in the capital, Addis Ababa. It is the premier higher education institution in the country, featuring multiple campuses, extensive postgraduate programs, and ranking high among East African universities.

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• RRID
• 7 months ago - submitted by Edyta Vieth

Database of age-related changes covering different biological levels, including molecular, physiological, psychological and pathological age-related data, to create an interactive portal that serves as a centralized collection of human aging changes and pathologies. To facilitate integrative, system-level studies of aging, the DAA provides a centralized source for aging-related data as well as basic tools to query and visualize the data, including anatomical models. Data in the DAA is manually curated from the literature and retrieved from public databases. For more detailed analyses users are able to download the entire database. More information on how to use the DAA is available on the help page. The DAA primarily focuses on human aging, but also includes supplementary mouse data, in particular gene expression data, to enhance and expand the information on human aging. If you would like to contribute to the database yourself, for instance if you have new data on aging, please use the contribute page to submit your data.

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• SciCrunch
• 14 years ago - by Anonymous

Commercial organism provider selling mice, rats and other model animals. American corporation specializing in a variety of pre-clinical and clinical laboratory services for the pharmaceutical, medical device and biotechnology industries. It also supplies assorted biomedical products and research and development outsourcing services for use in the pharmaceutical industry. (Wikipedia)

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• SciCrunch
• 13 years ago - by Anonymous

National facility providing advanced automated chemical and genetic in vivo screening for researchers, utilizing zebrafish embryos for studying disease mechanisms. Dedicated zebrafish-focused research imaging and screening facility adapting and developing cutting edge edge microscopy for automated multiscale imaging.

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• RRID
• 6 months ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 4, 2023.Java program for characterizing the haplotype block structure and selecting haplotype tagging SNP (entry from Genetic Analysis Software)

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• SciCrunch
• 14 years ago - by Anonymous

A higher education institute for advanced undergraduate and graduate studies in France. The institute has fourteen teaching and research departments that span the humanities and sciences.

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• SciCrunch
• 16 years ago - submitted by Andrea Stagg

Neuroanatomy-anchored Information Management Platform for collaborative BICAN data generation developed by UTHealth Houston. Serves as metadata tracking engine to support generation, management, and sharing of brain research data. Integrates data production pipelines across brain banks, laboratories, sequencing centers, and data archives. Platform enables integrative and collaborative, consortium-scale FAIR data generation within the BICAN project. Platform is designed to manage complex dataset, including tissue samples and sequencing data, through Specimen Portal and Sequence Library Portal. Portals provide multiple types of data interfaces through dashboards, APIs, faceted queries, and batch data ingestion and exporting.

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• RRID
• 6 months ago - submitted by Guo-Qiang Zhang

THIS RESOURCE IS NO LONGER IN SERVCE, documented September 6, 2016.

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• SciCrunch
• 14 years ago - by Anonymous

A privately held spinal company that is driving significant technological advancements across a complete suite of spinal products. Founded in 2003, Globus'' single-minded focus on advancing spinal surgery has made it the fastest growing company in the history of orthopedics. Globus is driven to utilize superior engineering and technology to achieve pain free, active lives for all patients with spinal disorders. The ultimate goal at Globus is to deliver innovation by utilizing superior engineering and technology to help improve patients'' lives. This clinical inspiration is central to every endeavor we undertake. We have developed a Spine Innovation Engine to focus our efforts on delivering industry leading solutions to surgeons and their patients. Our Spine Innovation Engine has developed a portfolio that includes a comprehensive line of technologically-advanced spine products. To date we have released over 50 major products and have over 30 more in various stages of development. Clinical Studies are the foundation for advancing innovative spine care and Globus is committed to a robust investment into prospective and retrospective clinical trials to evaluate the safety and efficacy of our products. Globus is currently conducting several FDA-approved Investigational Device Exemption (IDE) clinical studies.

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• SciCrunch
• 16 years ago - by Anonymous

Facility supports micro- and nanoscale fabrication, microsensor development, and atomic-scale materials synthesis. Provides comprehensive technical capabilities, including microlithography (mask aligners, photoresist processing, laser lithography), thin film deposition (e-beam evaporation, sputtering, PECVD, atomic layer deposition), and advanced characterization tools (profilometry, spectroscopic ellipsometry). Fabrication processes are supported by both dry etching (DRIE, RIE) and wet chemical processing (RCA clean, KOH etch, solvent benches), as well as thermal processing systems such as diffusion furnaces and rapid thermal annealing.

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• RRID
• 6 months ago - by Anonymous

A collection of tools for MRI T1 brain image segmentation in the Windows environment. It helps construct a complete pipeline with necessary preprocessing and postprocessing procedures besides brainparser, the core program of our fast brain segmentation. The execution of the whole pipeline can be completed in 2 hours with good segmentation results. Execution requires: FSL

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• SciCrunch
• 13 years ago - by Anonymous

An Antibody supplier

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• SciCrunch
• 14 years ago - by Anonymous

Core offers custom peptide services. Facility provides expertise and instrumentation dedicated to chemical synthesis, purification, and characterization of peptides and peptide materials. Provides standard and catalog peptides, and synthesis of specialty custom peptides modified to fit specific research needs.

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• RRID
• 6 months ago - by Anonymous

This central project points to all open-source and open-data initiatives provided by the German Cancer Research Center in the field of diffusion MRI.

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• SciCrunch
• 13 years ago - by Anonymous

MPI Research exists to provide comprehensive discovery, safety evaluation, bioanalytical, and analytical services that meet the requirements of biopharmaceutical, medical device, animal health, and chemical companies as we partner globally to bring safer and more effective products to the world. Our goal is to exceed the expectations of our Sponsors and maintain the highest respect in our industry by providing customized, responsive, and on-time services that add value to our Sponsors'' efforts to discover, develop, and enhance products in regulated international environments. We excel as a high performance, high quality organization because of our scientific knowledge and experience, integrity, trust, teamwork, and dedication to strong and enduring Sponsor relationships. MPI Research has conducted thousands of drug safety, discovery, bioanalytical, and analytical studies. We offer extensive support and resources including, but not limited to * A wide and diverse range of classes of compounds * All routes of administration except inhalation * Studies with numerous species and models * Comprehensive reporting capabilities Flexibility and ample capacity enable us to * Accommodate multiple requirements simultaneously * Adjust schedules readily * Produce results quickly Responding to a broad spectrum of research needs: Working in partnership with pharmaceutical, biotech, medical device, and chemical companies, we conduct customized preclinical research throughout the discovery and development process, from early proof of concept testing to regulatory submissions, including IND, EPA/OPPTS, NDA, PMA, and 510K.

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• SciCrunch
• 16 years ago - by Anonymous

Core provides high-plex immunohistochemistry (PhenoCycler/CODEX) on human and mouse FFPE tissues, image analysis (IHC, mIHC, high-plex), and support for collaborative and fee-for-service projects.

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• SciCrunch
• 6 months ago - submitted by Edyta Vieth

GAMMA suite is an open-source cross-platform data mining software package designed to analyze neuroimaging data. A neuroimaging study often focuses on biomarker detection and classification. We designed and implemented a Bayesian, multivariate, nonparametric suite of algorithms for analyzing neuroimaging data. The GAMMA suite can be used for brain morphometric analysis, lesion-deficit analysis, and functional MR data analysis.

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• SciCrunch
• 13 years ago - by Anonymous

Biotechnology company that develops products for genomics research and molecular diagnostics, such as systems for DNA and protein analysis, DNA and protein fractionation technologies, and other sequencing equipment.

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• RRID-Legacy
• 10 years ago - submitted by Ivan Erill