Curator Dashboard

Software R package for splitting, applying and combining data. Used to split up big data structure into homogeneous pieces, apply function to each piece and then combine all the results back together.

• Resource
• RRID
• 1 year ago - by Anonymous

The database of protein-chemical structural interactions includes all existing 3D structures of complexes of proteins with low molecular weight ligands. When one considers the proteins and chemical vertices of a graph, all these interactions form a network. Biological networks are powerful tools for predicting undocumented relationships between molecules. The underlying principle is that existing interactions between molecules can be used to predict new interactions. For pairs of proteins sharing a common ligand, we use protein and chemical superimpositions combined with fast structural compatibility screens to predict whether additional compounds bound by one protein would bind the other. The current version includes data from the Protein Data Bank as of August 2011. The database is updated monthly.

• Resource
• SciCrunch
• 15 years ago - by Anonymous

Database for evolutionary biochemical studies of caspase functional divergence and ancestral sequence inference. Tool to rapidly disseminate organized caspase sequence data. Includes all animal species with currently available annotated genomes in NCBI genome database. Manually curated and not curated sequences are available to download.

• Resource
• RRID-Legacy
• 6 years ago - by Anonymous

Software function as Matlab implementation of the TFA as specified in the White Paper (2015). An example of use on the supplied data (tfa_sample_data.txt) is given in tfa_demo.m and results are reported at the end of this report.

• Resource
• RRID
• 1 year ago - by Anonymous

KNIME (Konstanz Information Miner) is a user-friendly and comprehensive Open-Source data integration, processing, analysis, and exploration platform. KNIME (naim) is a user-friendly graphical workbench for the entire analysis process: data access, data transformation, initial investigation, powerful predictive analytics, visualization and reporting. The open integration platform provides over 1000 modules (nodes), including those of the KNIME community and its extensive partner network. KNIME can be downloaded onto the desktop and used free of charge. KNIME products include additional functionalities such as shared repositories, authentication, remote execution, scheduling, SOA integration and a web user interface as well as world-class support. Robust big data extensions are available for distributed frameworks such as Hadoop. KNIME is used by over 3000 organizations in more than 60 countries. The modular data exploration platform, initially developed at the University of Konstanz, Germany, enables the user to visually create data flows, execute selected analysis steps, and later investigate the results through interactive views on data and models. KNIME is a proven integration platform for tools of numerous vendors due to its open and modular API. The KNIME.com product pipeline includes an Enterprise Server, Cluster Execution, Reporting solutions, and professional KNIME support subscriptions. KNIME.com also offer services such as data analysis, hands-on training and the development of customized components for KNIME.

• Resource
• SciCrunch
• 15 years ago - by Anonymous

Facility dedicated to high resolution electron cryomicroscopy and electron cryotomography. It houses three electron microscopes,120kV Spirit, 200kV F20, and 300kV Titan Krios. These microscopes are available to researchers either for direct use, or aided by MEMC personnel, to collect data aimed at high resolution structural biology projects.

• Resource
• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Nectin4 Gene in Situ hybridization probe and centromeric control regions to determine copy number alterations of NECTIN4 gene relative to control centromeric region.

• Resource
• RRID
• 1 year ago - submitted by Markus Eckstein

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 1, 2022. Organization whose mission is to build and promote a sustainable ecosystem of professional societies, funding agencies, foundations, companies, and citizens together with life science researchers and innovators in computing, infrastructure and analysis with the expressed goal of translating new discoveries into tools, resources and products.

• Resource
• SciCrunch
• 15 years ago - by Anonymous

International initiative led by team of researchers and clinicians and supported by the US Cystic Fibrosis Foundation that seeks to provide complete, advanced and expert reviewed functional and clinical information on CFTR mutations. Provides information for patients, researchers, and general public about specific variants. For each variant or variant combination included in database, website will provide information about whether variant or variant combination is CF-causing, and information about sweat chloride, lung function, pancreatic status, and Pseudomonas infection rate in patients in CFTR2 database with this variant or variant combination.

• Resource
• RRID-Legacy
• 6 years ago - by Anonymous

Software R package for storing the regulons. Gene regulatory network containing signed transcription factor (TF) - target gene interactions. DoRothEA regulons, the collection of TF and its transcriptional targets, were curated and collected from different types of evidence for both human and mouse. Confidence level was assigned to each TF-target interaction based on number of supporting evidence.

• Resource
• RRID
• 1 year ago - by Anonymous

A patient registry to identify people with neurofibromatosis (NF) who are interested in participating in clinical trials, as well as determining the commonality of specific characteristics of NF. The NF Registry is committed to secure methodologies and pioneering research that will lead to improving the health and well-being of individuals and families affected by NF. This registry has been created to collect data on large numbers of people with NF. This has never existed before and will help: * Identify people who may be eligible for clinical trials or other research studies being conducted in the field of NF. New clinical trials are launched each year yet challenges identifying participants too often mean that these studies finish late or never really get started. Today, 80 percent of trials fail to recruit enough volunteers within planned timelines. Under enrollment is one of the most significant problems facing NF drug development. Together, we can solve it. * Determine the commonality of specific NF characteristics. This will help researchers and doctors devise better ways to care for people with NF If you or your child has been diagnosed with neurofibromatosis (NF) please join the NF Registry today. It''s quick, it''s easy, and it matters. The key to treatments lies within you researchers can''t deliver treatments without committed volunteers.

• Resource
• SciCrunch
• 14 years ago - by Anonymous

Software tool as rRNA marker gene amplicon pipeline coded in python framework that enables fine tuning and integration of virtually any potential rRNA gene amplicon bioinformatic procedure. Designed to work within HPC environment, supporting complex network of job dependencies with smart restart mechanism in case of job failure or parameter modifications.

• Resource
• SciCrunch
• 6 years ago - submitted by Julien Tremblay

Core provides library prep and NGS services using Illumina NextSeq 2000. Our services include sample QC, DNA, RNA bulk sequencing, single cell sequencing, and Sanger sequencing.

• Resource
• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Data set of almost 2,000 neurosurgical images using a variety of search options.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Silhouette images of animals, plants, and other life forms, available for reuse. Database stores reusable silhouette images and phylogenetic taxonomy of all organisms. Each image is associated with one or more taxonomic names and indicates roughly what ancestral member of each taxon looked like.

• Resource
• RRID-Legacy
• 6 years ago - by Anonymous

Research university in Poznań, Poland. It traces its origins to 1611, when under the Royal Charter granted by King Sigismund III Vasa, the Jesuit College became the first university in Poznań.

• Organization
• SciCrunch
• 13 years ago - submitted by Andrea Stagg

API for requesting images from Global-Multi Resolution Topography (GRMT).

• Resource
• SciCrunch
• 12 years ago - by Anonymous

Core helps researchers identify and interpret patterns in RNA and DNA by placing sequencing data into biologically meaningful context. Services include experimental design, developing reproducible workflows, analyzing next-generation sequencing data, and supporting manuscript development/publication.

• Resource
• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Facility provides access to imaging equipment and analysis tools. It houses widefield, laser scanning confocal, spinning disk confocal, multi-photon, light-sheet, and super-resolution microscopes, along with two transmission electron microscopes and high-content screener. Offers centralized workstation for image processing, high-performance computing capabilities, and data storage. Provides access to several commercial software programs for image analysis and data quantification. Services include consultations for sample preparation, training on the microscopes, full imaging support, and assistance with analysis strategies. Provides several services related to transmission electron microscopy: tissue/cell processing, image acquisition training or assistance, and image analysis support. CoRE scientists can collaborate with investigators to develop novel imaging methods and analysis approaches.

• Resource
• RRID
• 1 year ago - submitted by Edyta Vieth

Database that aggregates and markets technologies from CTSA institutions as well as those of the National Institutes of Health, with the goal of enhancing research activity and private partnerships across the CTSA consortium. Regular, automatic updating with a standardized template facilitates broad participation by CTSA consortium members. Currently, there are over a dozen CTSAs contributing information on their technologies to the site. CTSA-IP Mission * Intellectual Property information exchange * Links publicly available licensing opportunities from CTSI Institutions in an easily searchable format that connects providers & users. * Aim of creating a consortium view of IP, licensing & sponsored research opportunities. * Stimulus to collaboration and partnering with and between CTSA member institutions.

• Resource
• SciCrunch
• 14 years ago - by Anonymous