Curator Dashboard

Software R package for estimation, testing and regression modeling of subdistribution functions in competing risks.

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• SciCrunch
• 3 years ago - submitted by Edyta Vieth

Software that allows large scale neuron simulators to communicate during runtime. It allows exchange of data among parallel applications in a cluster environment, interconnects large-scale neuronal network simulators with each other or with other tools, participates in multi-simulations, and is continuously developed and extended. Three simulators currently have MUSIC interfaces: Moose, NEURON and NEST. Three applications execute in parallel while exchanging data via MUSIC. The software interface promotes interoperability by allowing models written for different simulators to be simulated together in a larger system. It enables re-usability of models or tools by providing a standard interface. As data are distributed over a number of processors, it is non-trivial to coordinate data transfer so that it reaches the correct destination at the correct time. Current and future simulators can make use of MUSIC - compliant general purpose tools and participate in multi-simulations, for example when: * Different parts of a complex nervous system model are optimally implemented in different simulators, and need to communicate with each other. * Post-processing of generated data is needed, where the amounts of data are too large for intermediate storage, and requires the simulator to pass the data directly to the post-processing module. A standard interface enables straight-forward independent third-party development and community sharing of interoperable software tools for parallel processing. * Library and utilities are written in C++, uses MPI. * It is possible to add a MUSIC interface to existing simulators. * Works independently, no assumptions are made about other applications to facilitate development of general purpose tools. * Performance Data transport with high bandwidth and low latency.

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• SciCrunch
• 17 years ago - by Anonymous

Institute dedicated to research in immunology by utilizing the academic and research communities in the La Jolla area as well as technological advances in biomedical research, imaging and analysis. Specific topics include autoimmune disease, cancer, allergies, infectious diseases and inflammation.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Software R package for clinical trial simulations based on Clinical Scenario Evaluation approach. The package supports broad class of data models, analysis strategies and commonly used evaluation criteria.

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• SciCrunch
• 3 years ago - submitted by Edyta Vieth

An analysis and visualization software tool for high dimensional flow cytometry data that organizes cells into hierarchies of related phenotypes.

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• SciCrunch
• 12 years ago - by Anonymous

Core facility that provides sequencing services, access to equipment and consultation on experimental design and data analysis. Available instruments include the Life Technologies Ion Torrent PGM and Ion Proton sequencers. Core also provides amplification-free analysis of RNA expression using the NanoString nCounter, and additionally provides sequencing and analysis services to investigators outside of SBP. Included in the cost of sequencing is basic bioinformatic analysis (SNP/InDel calling, transcript abundance). Lastly, the core also provides advice on experimental design, and guidance on the capabilities of next-generation sequencing.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Software R package finds the k nearest neighbours for every point in a given dataset in O(N log N) time using Arya and Mount's ANN library (v1.1.3).

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• SciCrunch
• 3 years ago - submitted by Edyta Vieth

Dendritica is a program package for relating dendritic geometry and signal propagation. The programs are based on those used for the simulations described in the following paper: Vetter, P., Roth, A. & Husser, M. (2001). Action potential propagation in dendrites depends on dendritic morphology. Journal of Neurophysiology, 85: 926-937. Dendritica can functionally be divided into three main parts: - Interactive morphological analysis and electrophysiological simulation of single cells - Automated batch simulations across a set of morphologies using the same simulation parameters - Automated analysis of batch simulation runs Dendritica requires NEURON 4.1.1 with some modifications described in Appendix 1. It was tested for NEURON 4.1.1 on Linux and SGI IRIX. Some modifications to the Dendritica code may be necessary in order to run it on older or newer versions of NEURON. Sponsors: This work was supported by the Wellcome Trust, the European Community, the Max-Planck-Gesellschaft, the Wellcome Trust 4-year PhD Programme in Neuroscience.

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• SciCrunch
• 17 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. A website that provides access to a database, nomenclature, fac sheets, downloadable slides, and other information regarding RB1 gene mutations.

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• SciCrunch
• 17 years ago - by Anonymous

Software package as Java based common sequence file format reader and sequence file manipulation.

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• SciCrunch
• 3 years ago - submitted by Edyta Vieth

Database providing a sequence-centered genome view for Arabidopsis thaliana, with a narrow focus on gene structure annotation. The current genome assembly displayed at AtGDB is version TAIR9. Annotated gene models are TAIR10. They have mapped the complete set of 176,915 publicly available Arabidopsis EST sequences onto the Arabidopsis genome using GeneSeqer, a spliced alignment program incorporating sequence similarity and splice site scoring. About 96% of the available ESTs could be properly aligned with a genomic locus, with the remaining ESTs deriving from organelle genomes and non-Arabidopsis sources or displaying insufficient sequence quality for alignment. The mapping provides verified sets of EST clusters for evaluation of EST clustering programs. Analysis of the spliced alignments suggests corrections to current gene structure annotation and provides examples of alternative and non-canonical pre-mRNA splicing.

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• SciCrunch
• 17 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. FUGOID is a database for functional genomics of organelle introns. The taxonomically broad organelle intron database contains comprehensive functional and structural information on organellar (mitochondria and chloroplast) introns. FUGOID collects and integrates various structural and functional data on organellar (mitochondrial and chloroplast) introns, particularly functional information about intron splicing and mobility. It is implemented in a relational database management system and can be searched either by intron information or by a major reference. Data entry and revision systems have also been developed.

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• SciCrunch
• 17 years ago - by Anonymous

Software toolbox provides set of basic functions allowing SBML models to be used in both MATLAB and Octave.

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• SciCrunch
• 3 years ago - submitted by Edyta Vieth

International society dedicated to advancing understanding of anatomical and functional organization of human brain using neuroimaging. Primary function of society is to provide educational forums for exchange of up-to-the-minute and groundbreaking research across neuroimaging methods and applications. OHBM achieves this through its member led committees and Annual Meeting that is held in different locations throughout the world.

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• SciCrunch
• 17 years ago - by Anonymous

Desktop software suite targeted to curators and experimentalists that assists in the reporting and local management of experimental metadata, engages with minimum information checklists and ontologies and formats studies for submission to international public repositories. The ISA software suite is the product of an ongoing collaboration between various research and service groups from diverse life science domains. It represents an opportunity for the wider research community to start taking data management into their own hands by supporting graduated adherence to community standards and the efficient curation of experimental metadata at source, shielded from underlying complexities. The software suite is comprised of several platform-independent Java-based software components for local use, including a relational database, built around the ISA-Tab format. The components work both as stand-alone applications and as a unified system.

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• SciCrunch
• 17 years ago - by Anonymous

Software for alignment free sequence comparison. Uses pattern of care and don't care positions. Compares frequencies of spaced words according to pre-defined pattern.

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• SciCrunch
• 3 years ago - submitted by Edyta Vieth

A common portal for minimum information (MI) checklists to act as a one-stop shop for those exploring the range of extant projects, foster collaborative development and ultimately promote gradual integration. Goals include * To increase the visibility of projects developing guidance for the reporting of biological and biomedical science. * To encourage appropriate collaborative development between projects to avoid duplication of effort or competition. * To promote the adoption of consensus guidance on reporting by journals and funders.

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• SciCrunch
• 17 years ago - by Anonymous

Group Sparse Canonical Correlation Analysis is a method designed to study the mutual relationship between two different types of data.

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• NIF
• 10 years ago - submitted by Matt Travers

Software tool as structural variant calling.

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• SciCrunch
• 3 years ago - submitted by Edyta Vieth

Database of publicly available pathways from multiple organisms and multiple sources represented in a common language. Pathways include biochemical reactions, complex assembly, transport and catalysis events, and physical interactions involving proteins, DNA, RNA, small molecules and complexes. Pathways were downloaded directly from source databases. Each source pathway database has been created differently, some by manual extraction of pathway information from the literature and some by computational prediction. Pathway Commons provides a filtering mechanism to allow the user to view only chosen subsets of information, such as only the manually curated subset. The quality of Pathway Commons pathways is dependent on the quality of the pathways from source databases. Pathway Commons aims to collect and integrate all public pathway data available in standard formats. It currently contains data from nine databases with over 1,668 pathways, 442,182 interactions,414 organisms and will be continually expanded and updated. (April 2013)

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• SciCrunch
• 17 years ago - by Anonymous