Curator Dashboard

A unified resource that combines text-based and 3D graphical methods to store, display, and analyze mouse developmental gene expression information. The Mouse Gene Expression Information Resource resource will integrate the following components: * Gene Expression Database (GXD) - Integrates different types of expression data and provides links to many other resources to place the data into the larger biological and analytical context. * Anatomy Database - Provides the standard nomenclature for developmental anatomy. * 3D Atlas / Graphical Gene Expression Database - Provides a high-resolution digital representation of mouse anatomy reconstructed from serial sections of single embryos at each representative developmental stage enabling 3D graphical display and analysis of in situ expression data.

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• SciCrunch
• 17 years ago - by Anonymous

Public research university located in Guanshan Subdistrict, Hongshan District, Wuhan, Hubei province, China.

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• SciCrunch
• 15 years ago - submitted by Andrea Stagg

Software that archives evidence collected from different sources, then analyzes and presents these data. Its data come from manually curated protein-protein interaction databases that have adhered to the IMEx consortium.

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• RRID-Legacy
• 9 years ago - by Anonymous

Web game that provides an innovative infrastructure for labeling to enable an alternative to expert raters for medical image labeling through statistical analysis of the collaborative efforts of many, minimally-trained raters. Statistical atlases of regional brain anatomy have proven to be extremely useful in characterizing the relationship between the structure and function of the human nervous system. Typically, an expert human rater manually examines each slice of a three-dimensional volume. This approach can be exceptionally time and resource intensive, so cost severely limits the clinical studies where subject-specific labeling is feasible. Methods for improved efficiency and reliability of manual labeling would be of immense benefit for clinical investigation into morphological correlates of brain function.

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• SciCrunch
• 13 years ago - by Anonymous

Public research university in Berlin, Germany. The Free University of Berlin is one of eleven elite German research universities in the German Universities Excellence Initiative.

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• SciCrunch
• 13 years ago - submitted by Andrea Stagg

Gene Expression Atlas is a semantically enriched database of meta-analysis based summary statistics over a curated subset of ArrayExpress Archive, servicing queries for condition-specific gene expression patterns as well as broader exploratory searches for biologically interesting genes/samples. The EBI Gene Expression Atlas Blog discusses ideas, features and problems of creating a large scale meta-analytical atlas of gene expression from publicly available microarray data. Atlas REST API provides all the results available in the main web application in a pragmatic, easy to use form - simple HTTP GET queries as input and either JSON or XML formats as output. Gene Expression Atlas goals: 1. Provision of a statistically robust framework for integration of gene expression experiment results across different platforms at a meta-analytical level 2. A simple interface for identifying strong differential expression candidate genes in conditions of interest 3. Integration of ontologies for high quality annotation of gene and sample attributes 4. Construction of new gene expression summarized views, with a view to analysis of putative signaling pathway targets, discovery of correlated gene expression patterns and the identification of condition/tissue-specific patterns of gene expression.

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• SciCrunch
• 17 years ago - by Anonymous

Biomedical technology research center that provides expertise for the design of quantitative magnetic resonance imaging (MRI) and spectroscopy (MRS) data acquisition and processing technologies that facilitate the biomedical research of a large community of clinicians and neuroscientists in Maryland and throughout the USA. These methods allow noninvasive assessment of changes in brain anatomy as well as in tissue metabolite levels, physiology, and brain functioning while the brain is changing size during early development and during neurodegeneration, i.e. the changing brain throughout the life span. The Kirby Center has 3 Tesla and 7 Tesla state of the art scanners equipped with parallel imaging (8, 16, and 32-channel receive coils) and multi-transmit capabilities. CIS has an IBM supercomputer that is part of a national supercomputing infrastructure. Resources fall into the following categories: * MRI facilities, image acquisition, and processing * Computing facilities and image analysis * Novel statistical methods for functional brain imaging * Translating laboratory discoveries to patient treatment

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• SciCrunch
• 14 years ago - by Anonymous

A Louisiana-based university with programs in dentistry, medicine, public health, patient care and allied health professions. This university Includes a graduate program in fields including neuroscience, pharmacology, and genetics.

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• SciCrunch
• 14 years ago - submitted by Andrea Stagg

A database of three-dimensional protein structures. It contains molecules, complexes, sequences, ligand/receptor pairings, and other useful tools. Currently, 1655 entries are managed , with 1602 IMGT/3Dstructure-DB cards (PDB) and 53 IMGT/2Dstructure-DB cards (INN).

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• SciCrunch
• 17 years ago - by Anonymous

It is a collection of selected human-focused cellular pathways implicated in cancer that are linked to visualization and analysis tools. Biologists can browse and search the Cancer Cell Map pathways and view gene expression data on any pathway. All data is freely available. Computational biologists can download all pathways in BioPAX format for global analysis. Software developers can build software on top of the Cancer Cell Map using the web service API. Download and install the cPath pathway database software to create a local mirror of the Cancer Cell Map. Cancer Cell Map pathways were selected based on the scientific interests of research labs at Memorial Sloan-Kettering Cancer Center. Effort was made not to duplicate information in other public pathway databases. Available pathways include: Alpha6Beta4Integrin, AndrogenReceptor, EGFR1, Hedgehog, ID, KitReceptor, NOTCH, TGFBR, TNF alpha/NF-kB, Wnt. Each pathway has around 100-400 interactions.

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• SciCrunch
• 14 years ago - by Anonymous

Medical university that specializes in health sciences, medical arts, public advocacy, and allied health profession training.

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• SciCrunch
• 17 years ago - submitted by Andrea Stagg

High quality ribosomal RNA databases providing comprehensive, quality checked and regularly updated datasets of aligned small (16S/18S, SSU) and large subunit (23S/28S, LSU) ribosomal RNA (rRNA) sequences for all three domains of life (Bacteria, Archaea and Eukarya). Supplementary services include a rRNA gene aligner, online tools for probe and primer evaluation and optimized browsing, searching and downloading on the website. The extensively curated SILVA taxonomy and the new non-redundant SILVA datasets provide an ideal reference for high-throughput classification of data from next-generation sequencing approaches. Alignment tool, SINA, is available for download as well as available for use online.

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• SciCrunch
• 13 years ago - by Anonymous

The Epilepsy Genetic Association Database (epiGAD) is an online repository of data relating to genetic association studies in the field of epilepsy. It summarizes the results of both published and unpublished studies, and is intended as a tool for researchers in the field to keep abreast of recent studies, providing a bird''s eye view of this research area. The goal of epiGAD is to collate all association studies in epilepsy in order to help researchers in this area identify all the available gene-disease associations. Finally, by including unpublished studies, it hopes to reduce the problem of publication bias and provide more accurate data for future meta-analyses. It is also hoped that epiGAD will foster collaboration between the different epilepsy genetics groups around the world, and faciliate formation of a network of investigators in epilepsy genetics. There are 4 databases within epiGAD: - the susceptibility genes database - the epilepsy pharmacogenetics database - the meta-analysis database - the genome-wide association studies (GWAS) database The susceptibility genes database compiles all studies related to putative epilepsy susceptibility genes (eg. interleukin-1-beta in TLE), while the pharmacogenetics studies in epilepsy (eg. ABCB1 studies) are stored in ''phamacogenetics''. The meta-analysis database compiles all existing published epilepsy genetic meta-analyses, whether for susceptibility genes, or pharmacogenetics. The GWAS database is currently empty, but will be filled once GWAS are published. Sponsors: The epiGAD website is supported by the ILAE Genetics Commission.

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• SciCrunch
• 17 years ago - by Anonymous

We are a vibrant community of educators, students, scientists, clinicians and others working side-by-side to heal, teach, discover and serve. We support 1,750 faculty, 1,200 students and 750 residents and fellows in 27 departments and 17 centers and institutes. We offer doctorates in medicine and philosophy, masters in science, public health and physician assistant studies and combined degrees. Our faculty is dedicated to preparing physicians for the medical, ethical and humanistic responsibilities of their calling, while also providing outstanding care to patients from Oregon and elsewhere. Along with the art of teaching and healing comes the responsibility for discovery. The School of Medicine faculty is widely recognized nationally and internationally for the pursuit of new knowledge in a breadth of investigative areas ranging from molecular biology and cancer to heart disease, behavioral science and issues of public health.

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• SciCrunch
• 15 years ago - submitted by Andrea Stagg

Database containing information on marketed medicines and their recorded adverse drug reactions. The information is extracted from public documents and package inserts. The available information include side effect frequency, drug and side effect classifications as well as links to further information, for example drug-target relations. The SIDER Side Effect Resource represents an effort to aggregate dispersed public information on side effects. To our knowledge, no such resource exist in machine-readable form despite the importance of research on drugs and their effects. The creation of this resource was motivated by the many requests for data that we received related to our paper (Campillos, Kuhn et al., Science, 2008, 321(5886):263-6.) on the utilization of side effects for drug target prediction. Inclusion of side effects as readouts for drug treatment should have many applications and we hope to be able to enhance the respective research with this resource. You may browse the drugs by name, browse the side effects by name, download the current version of SIDER, or use the search interface.

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• SciCrunch
• 16 years ago - by Anonymous

An open source tool to help researchers document, manage, and archive their tabular data that integrates with Microsoft Excel. The tool will parse .xlsx or .csv file to detect the presence of potential issues that do not comply with data management best practices, assign a unique identifier to a data set and deposit it within the DataONE repository system.

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• SciCrunch
• 14 years ago - by Anonymous

Public liberal arts college in Mahwah, New Jersey. It is part of New Jersey's public system of higher education.

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• SciCrunch
• 16 years ago - submitted by Eddy Kim

National facility for permanent curatorial preservation of rock collections from Antarctica and Southern Ocean. Repository preserves existing rock/dredge/unconsolidated/terrestrial core/photo archive collections for research use. Database allows online requests for sample loans. Mapping tool combines existing PRR database with high resolution satellite images of Antarctica, REMA or USGS topographic layers. PRR created Polar Rock Boxes for educators who are teaching about Earth science and Antarctica. Each Polar Rock Box contains samples with binder full of teaching information about Earth science and Antarctica. These boxes are freely available as short loans to US schools.

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• SciCrunch
• 14 years ago - by Anonymous

PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens. PLEXdb is a genotype to phenotype, hypothesis building information warehouse, leveraging highly parallel expression data with seamless portals to related genetic, physical, and pathway data. The integrated tools of PLEXdb allow investigators to use commonalities in plant biology for a comparative approach to functional genomics through use of large-scale expression profiling data sets.

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• SciCrunch
• 15 years ago - by Anonymous

Public research university in Carbondale, Illinois. Founded in 1869, SIU is the oldest campus of the Southern Illinois University system.

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• SciCrunch
• 17 years ago - submitted by Andrea Stagg