We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
THIS RESOURCE IS NO LONGER IN SERVICE, documented September 2, 2016. A clinical database and PTB were created in 1990 and 2000, respectively, to collect clinical information and biospecimens from patients with suspected or confirmed pancreatic cancer, other pancreatic diseases, and tumors of the duodenum, ampulla of Vater, and distal bile duct. Standard procedures for biospecimen collection and data entry were developed. The use of human tissue for research is an invaluable tool to understand the basic mechanisms of tumor biology, which will hopefully lead to the development of new therapeutic approaches to pancreatic cancer treatment. The cornerstone of any large translational research program is the development of an accurate and comprehensive tumor bank. All tumors removed in the operating room are sampled for careful pathologic study and the remainder of the tumor is promptly stored in our Pancreas Tissue Bank (PTB) to be used for research. Other samples, including blood, pancreatic juice and biopsy material, can also be utilized to identify early markers for pancreatic cancer. The molecular profile of tumors in the PTB can be linked to information in our clinical database to provide insight on the relationship between molecular events and clinical outcome. Patients may contribute to the tissue banking effort by choosing to participate in select research protocols. Protecting patient privacy is of great importance and thus, to maintain the confidentiality of health information, the PTB complies with all federal and institutional regulations governing research with human participants.
Core offers researchers, clinicians and biotech companies regulatory compliant labs and services to manufacture minimally manipulated and complex biotechnology products.
Core offers assistance in experimental design, sample preparation, library prep, sequencing, data analysis and bioinformatics. Provides experience working with non-human primate genomes and other non-standard genomes in addition to the more commonly studied human and mouse genomes. Provides expertise in the use of transcriptomics and genomics to study immune responses and repertoires.Houses Illumina NovaSeq 6000 and Illumina MiSeq.
TBI/Tissue Banks International is a non-profit network of medical eye and tissue banks dedicated to the relief of human suffering through transplantation. More than 100,000 patients are treated with TBI tissue annually. TBI is a recognized innovator in the field of eye and tissue banking and has led advancements in recovery, processing, and distribution of allograft tissue. Each person who chooses to become an eye and tissue donor can help more than a dozen people through their gift. Sight can be restored with a cornea, mobility enabled with a ligament, pain eased with a spinal implant made of bone, burns treated with skin, and lives saved with heart valves. The largest provider of ocular tissue in the world, TBI started as a single eye bank in 1962, and has grown to a network that covers the United States and reaches around the globe. Each year, more than 130,000 TBI tissues are used in transplant surgery, with thousands more utilized in research and medical education.
Software R package provides tools to infer proportions of priori known cell-types present in sample representing mixture of such cell-types. Comparison of reference based algorithms for correcting cell-type heterogeneity in Epigenome-Wide Association Studies.
Software R package for Affymetrix Affymetrix HG-U133_Plus_2 Array annotation data assembled using data from public repositories.
GenMAPP is a free computer application designed to visualize gene expression and other genomic data on maps representing biological pathways and groupings of genes. Integrated with GenMAPP are programs to perform a global analysis of gene expression or genomic data in the context of hundreds of pathway MAPPs and thousands of Gene Ontology Terms (MAPPFinder), import lists of genes/proteins to build new MAPPs (MAPPBuilder), and export archives of MAPPs and expression/genomic data to the web. The main features underlying GenMAPP are: *Draw pathways with easy to use graphics tools *Color genes on MAPP files based on user-imported genomic data *Query data against MAPPs and the GeneOntology Enhanced features include the simultaneous view of multiple color sets, expanded species-specific gene databases and custom database options.
Core provides access to computing infrastructure while offering technical support. Provide tools and instruction allowing for inclusion of high performance computing in classroom.
X.Org project provides open source implementation of X Window System. The development work is being done in conjunction with the freedesktop.org community. The X.Org Foundation is the educational non-profit corporation whose Board serves this effort, and whose Members lead this work.
The National Academy of Sciences (NAS) is a private, non-profit society of distinguished scholars engaged in scientific and engineering research, dedicated to the furtherance of science and technology and to their use for the public good. An Act of Congress, signed by President Abraham Lincoln in 1863 at the height of the Civil War, calls upon the NAS to provide independent advice to the government on matters related to science and technology. The National Research Council was created under the NAS charter in 1916 to extend the scope of the NAS in its advisory role. The National Academy of Engineering and the Institute of Medicine were organized under the NAS charter in 1964 and 1970, respectively. Since 1863, the nation''s leaders have turned to the National Academy of Sciences for advice on the scientific and technological issues that frequently affect policy decisions. Most of the institution''s science policy and technical work is conducted by the National Research Council (NRC), which was created expressly for this purpose and which provides a public service by working outside the framework of government to ensure independent advice on matters of science, technology, and medicine. The NRC enlists the nation''s top scientists, engineers, and other experts, who volunteer their time to study specific issues. The reports that result from their deliberations have led to some of the most significant and lasting improvements in the health, education, and welfare of all Americans. The Academy''s service to government has become so essential that Congress and the White House have issued legislation and executive orders over the years that reaffirm its unique role. NAS Award in the Neurosciences - Established by the Fidia Research Foundation Awarded in recognition of extraordinary contributions to progress in the fields of neuroscience, including neurochemistry, neurophysiology, neuropharmacology, developmental neuroscience, neuroanatomy, and behavioral and clinical neuroscience. The award is given every three years and will be awarded again in 2013
Software plugin for bone image analysis in ImageJ. Used for standard bone measurements. Provides free, open source tools for trabecular geometry and whole bone shape analysis.
Software tool for RNAi-target design and off-target prediction. Used for long double-stranded RNAi-target design and off-target prediction.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on March 17, 2022. A large-scale database of genetics and genomics data associated to a web-interface and a set of methods and algorithms that can be used for mining the data in it. The database contains two categories of single nucleotide polymorphism (SNP) annotations: # Physical-based annotation where SNPs are categorized according to their position relative to genes (intronic, inter-genic, etc.) and according to linkage disequilibrium (LD) patterns (an inter-genic SNP can be annotated to a gene if it is in LD with variation in the gene). # Functional annotation where SNPs are classified according to their effects on expression levels, i.e. whether they are expression quantitative trait loci (eQTLs) for that gene. SCAN can be utilized in several ways including: (i) queries of the SNP and gene databases; (ii) analysis using the attached tools and algorithms; (iii) downloading files with SNP annotation for various GWA platforms. . eQTL files and reported GWAS from NHGRI may be downloaded., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Public repository for archiving circular dichroism spectroscopic data and associated bioinformatics and experimental metadata. For authors to deposit experimental data as well as detailed information on methods and calculations associated with published work. Includes links for each entry to bioinformatics databases. Data are freely available to accessors either as single files or as complete data bank downloads.
Software package as set of tools, primarily shell scripts, for processing multi-modal, high-quality MRI images for the Human Connectome Project. Minimal preprocessing pipelines for structural, functional, and diffusion MRI that were developed by the HCP to accomplish many low level tasks, including spatial artifact/distortion removal, surface generation, cross-modal registration, and alignment to standard space.
A software tool for calling short indels in next generation sequencing data.
Core assists investigators whose research requires molecular marker characterization of cells in suspension as well as isolation of cells based on those markers. Advanced cell sorting and cytometric analyses by Flow or Mass Cytometry are provided.
Core provides microscopy services to departments at MD Anderson in high resolution and multispectral fluorescence microscopy for users from divisions including Basic Research, Cancer Medicine, Diagnostic Imaging, Surgery, Internal Medicine Pediatrics and Radiation Oncology, among others. Offers microscopy resources and expertise in fluorescence imaging to spatially and dynamically assess cells, tissues and their requisite contents across scales.
The Gene Wiki is a project that facilitates transferring information on human genes to Wikipedia article stubs with the goal of promoting collaboration and expansion of the articles. Number of gene articles The human genome contains an estimated 20,00025,000 protein-coding genes. The goal of the Gene Wiki project is to create seed articles for every notable human gene, that is, every gene whose function has been assigned in the peer-reviewed scientific literature. Approximately half of human genes have assigned function, therefore the total number of articles seeded by the Gene Wiki project would be expected to be in the range of 10,000 - 15,000. To date, approximately 10,271 articles have been created or augmented to include Gene Wiki project content. Expansion Once seed articles have been established, the hope and expectation is that these will be annotated and expanded by editors ranging in experience from the lay audience to students to professionals and academics. Proteins encoded by genes The majority of genes encode proteins hence understanding the function of a gene generally requires understanding of the function of the corresponding protein. In addition to including basic information about the gene, the project therefore also includes information about the protein encoded by the gene. Stubs for the Gene Wiki project are created by a bot and contain links to the following primary gene/protein databases * HUGO Gene Nomenclature Committee official gene name * Entrez Gene database * OMIM (Mendelian Inheritance in Man) database that catalogues all the known diseases with a genetic component * Amigo Gene Ontology * HomoloGene gene homologs in other species * SymAtlasRNA gene expression pattern in tissues * Protein Data Bank 3D structure of protein encoded by the gene * Uniprot (universal protein resource) a central repository of protein data
Software R package for species distribution modeling, calibration and evaluation, ensemble of models, ensemble forecasting and visualization.