Curator Dashboard

Software R package and ShinyApp for producing PRISMA 2020 compliant flow diagrams. ShinyApp for producing PRISMA 2020 compliant flow diagrams.

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• RRID-Legacy
• 6 years ago - by Anonymous

Core facility which provides mass spectrometry analyses to Diabetes Research Center investigators that includes quantification as well as structural characterization of diabetes-related biomolecules.

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• SciCrunch
• 10 years ago - submitted by Kristen Jensen

Ontology to define the abstract division of the total genetic information of an organism by its physical separation into different components, thereby providing a high level reference point to which more specific descriptions of the characteristics of these components can be linked.

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• SciCrunch
• 13 years ago - by Anonymous

Software R package to find and filter artificial chimeric reads specifically generated in next generation sequencing process of formalin fixed paraffin embedded tissues. These artificial chimeric reads can lead to large number of false positive structural variant calls. Artifact chimeric read filter to improve SV detection in FFPE samples.

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• SciCrunch
• 6 years ago - submitted by Lanying Wei

Core is dedicated to advancing biomedical discovery through modern and highly advanced imaging technologies. Provides access to high-resolution, non- and minimally invasive imaging tools that enable visualization of biological processes in vivo. Core offers imaging services including MR Solutions Multi-Field MRI systems (3T, 7T, and 9.4T) for detailed anatomical and functional imaging, the IVIS Lumina S5 platform for sensitive bioluminescence and fluorescence imaging, and the TriTom Photoacoustic Imager for high-contrast 3D photoacoustic visualization and multi-spectral imaging of molecular and vascular dynamics.Facility supports a wide range of preclinical applications. These include longitudinal animal studies, drug development, biomarker discovery, and validation of novel imaging agents.

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• SciCrunch
• 4 months ago - submitted by Edyta Vieth

A system of classifications to enable systematic description of how injuries occur. It is designed especially to assist injury prevention. It was originally designed for use in settings in which information is recorded in a way that allows statistical reporting--for example, injury surveillance based on collection of information about cases attending a sample of hospital emergency departments. It has also been found useful for other purposes. For example, it has been used as a reference classification during revision of another classification, to record risk-factor exposure of children in a cohort study, as the basis for special-purpose classifications and in a growing number of other ways.

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• SciCrunch
• 13 years ago - by Anonymous

Portal devoted to suite of MORF reporter mice labels of Cre positive neurons and glia distributed stochastically throughout brain and can be imaged with endogenous fluorescence (mNeonGreen in MORF1 and EGFP in TIGRE-MORF) or stained for multivalent immunoreporter (Spaghetti Monster fluorescent protein V5, or smFP-V5, in MORF3). MORF technology used to label and reconstruct thousands genetically defined cells per brain for large scale, unbiased classification and quantitative analyses of CNS cell types brainwide.

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• RRID-Legacy
• 5 years ago - submitted by Anita Bandrowski

Nanofabrication and characterization facility that provides open access to advanced cleanroom infrastructure, instrumentation, and technical expertise. Offers infrastructure for fabrication and characterization of nanoscale materials, systems and devices. Provides user training, process development assistance, and access to specialized expertise for research and prototyping.

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• RRID
• 4 months ago - submitted by Yousheng (Wilson) Lin

Ontology that contains the former BIRNLex-Disease, version 1.3.2. -- The BIRN Project lexicon provided entities for data and database annotation for the BIRN project, covering anatomy, disease, data collection, project management and experimental design. It was built using the organizational framework provided by the foundational Basic Formal Ontology (BFO). It used an abstract biomedical layer on top of that - OBO-UBO which was constructed as a proposal to the OBO Foundry. This was meant to support creating a sharable view of core biomedical objects such as biomaterial_entity, and organismal_entity that all biomedical ontologies are likely to need and want to use with the same intended meaning. The BIRNLex biomaterial entities have already been factored to separately maintained ontology - BIRNLexBiomaterialEntity.owl which this BIRNLex-Main.owl file imports. The Ontology of Biomedical Investigation (OBI) is also imported and forms the foundation for the formal description of all experiment-related artifacts. The BIRNLex will serve as the basis for construction of a formal ontology for the multiscale investigation of neurological disease.

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• SciCrunch
• 13 years ago - by Anonymous

Software framework for analysis of single cell chromatin data. Used for analysis, interpretation, and exploration of single cell chromatin datasets including datasets that co-assay DNA accessibility with gene expression, protein abundance, and mitochondrial genotype. Analysis of single-cell chromatin data including peak calling, quantification, quality control, dimension reduction, clustering, integration with single-cell gene expression datasets, DNA motif analysis, and interactive visualization.

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• RRID-Legacy
• 5 years ago - by Anonymous

Core facility provides genome editing services in vitro and in vivo for translational cancer research. Services span functional genomics (CRISPR screens across cells, organoids and patient-derived xenograft models, integrated with single-cell RNA sequencing), transgenics (embryo manipulation, pronuclear injection, electroporation, cryopreservation, and import/export of genetically modified models), and multimodal pre-clinical trials run through a dedicated Small Animal Hospital using genetically engineered, xenograft and orthotopic models. Offers experimental design consultation to match editing technologies to each research question.

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• RRID
• 3 months ago - submitted by Nadia Cross

Ontology used to model the scientific investigation, especially Genome-Wide Association Study (GWAS), to find out genetic susceptibility factor to disease, such as Diabetes. It models the genetic varaints, polymorphisms, statistical measurement, populations and other elements that are essential to determine a genetic susceptibility factor in GWAS study. It must be used with other two ontologies, in the case of Diabetes, :Ontology of Geographical Region (OGR) and Ontology of Glucose Metabolism Disorder (OGMD) .

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• SciCrunch
• 13 years ago - by Anonymous

Provides either dynamic or static control of O2 and CO2 conditions for animal modeling when used in combination with one or two A-Chamber Animal Chamber(s).

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• SciCrunch
• 5 years ago - submitted by Ray Gould

National, peer led consortium of institutions that advocates for systemic changes to improve research quality, training, and open science practices. It unites researchers, universities, funders, and publishers to promote open research practices, share best practices, and reform how researchers are evaluated and rewarded. Provides training resources and workshops to help researchers adopt transparent methods, such as sharing open data and code. It operates grassroots local networks at universities across the country, connecting researchers to exchange ideas and collaborate across different career stages and disciplines.

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• RRID
• 3 months ago - submitted by anita bandrowski

Ontology that models provenance metadata associated with experiment protocols used in parasite research. The PEO extends the upper-level Provenir ontology (http://knoesis.wright.edu/provenir/provenir.owl) to represent parasite domain-specific provenance terms. The PEO (v 1.0) includes Proteome, Microarray, Gene Knockout, and Strain Creation experiment terms along with other terms that are used in pathway.

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• SciCrunch
• 13 years ago - by Anonymous

Software R package of igraph network analysis library.

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• RRID-Legacy
• 5 years ago - by Anonymous

Software R package to integrate and query microRNA (miRNA) data. It allows retrieve and analyze validated and predicted miRNA-target interactions, as well as their associations with various diseases and drugs.

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• RRID
• 3 months ago - submitted by Kemal Ugur Tufekci

Ontology in the domain of role classification that aims to standardize role classification and support computer-assisted reasoning. RoleO is a community-based ontology, and its development follows the OBO Foundry principles.

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• SciCrunch
• 13 years ago - by Anonymous

Comprises six service groups. Our services are available to all NIH intramural researchers, and by interagency agreements to FDA and US Army at Ft. Detrick. We are happy to consult and distribute materials to not-for-profit institutions.Clone Optimization service include DNA cloning for protein expression; Gateway-based; fluorescent, epitope, solubility, purification tags; mutagenesis; vectors for insect/ baculovirus, mammalian, E. coli, P. pastoris, K. lactis. Microbial Expression: E. coli, P. pastoris, K. lactis, 2 mL to 60 L, autoinduction and IPTG; fully instrumented fermenters.Eukaryotic Expression service include insect / baculovirus, mammalian transient and stable, monoclonal antibodies.Protein Purification service include parallel microscale for process development; affinity and native, tag and endotoxin removal; scale-up to low gram scale.Virus Technology service include custom and stock adenovirus and lentivirus production; titer determination; promoter and reporter panels in lentivirus ready to deliver.Molecular Detection: qPCR and ELISA assaysdeveloped and executed, focused on human viruses in human samples; qPCR assays for mycoplasma and human pathogenic viruses contaminating cell lines; cell line identity testing.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Core offers nanofabrication services and tools for lithography, deposition, etch, and characterization. Used for researching, building, and measuring materials on a microscopic scale. Provides cleanroom space and advanced tools for academic and industry projects.

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• RRID
• 3 months ago - by Anonymous