We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
One of the largest public universities in Mexico.
Software package for quantifying transposable elements at a locus level for RNAseq datasets. TElocal base algortihm is derived from the published TEtranscripts tool.
Organization that facilitates spinal cord injury research and care. By accelerating the translation of discoveries and best practices into improved treatments, it aims to improve the lives of people living with SCI.
The Salk Institute conducts research within three major areas of study: Molecular Biology and Genetics; Neurosciences; and Plant Biology. Six key areas represent strategic research priorities: Chemistry and Proteomics; Stem Cell Biology; Cell Biology; Regulatory Biology; Metabolic Research; and Computational and Theoretical Biology.
Core provides access to advanced imaging and analytical instrumentation, expert technical support, hands-on training, and collaborative project support. Services include high-resolution imaging through Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) to examine surface features, internal structures, microstructures, nanoparticles, biological specimens, and engineered materials at micro- to nanoscale resolution; X-Ray Diffraction (XRD) for phase determination and crystallographic analysis; Atomic Force Microscopy (AFM) for nanoscale surface characterization. Provides solid analyzer and rheometer for evaluating material properties and behavior. Specialized sample preparation services include polishing, ultramicrotomy, sputter coating, and other preparation techniques needed for microscopy and materials analysis. Individualized, non-credit instruction is available for instrument operation and sample prep techniques. Offers expert support with sample preparation, data acquisition, sample analysis, troubleshooting, and preparation of results for reports, proposals, presentations, and publications.
The Transgenic Hydra Facility is a non-profit facility in the laboratory of Thomas Bosch at the University of Kiel that assists scientists to use and to develop transgenic Hydra polyps. Our mission is to provide investigators access to the latest technology for the efficient production of transgenic polyps. We particularly encourage scientists from laboratories lacking the infrastructure for transgenic Hydra technologies to use our services. Abstract: Understanding the evolution of development in large part relies on the study of phylogenetically old organisms. Cnidarians, such as Hydra, have become attractive model organisms for these studies. However, despite long-term efforts, stably transgenic animals could not be generated, severely limiting the functional analysis of genes. Here we report the efficient generation of transgenic Hydra lines by embryo microinjection. One of these transgenic lines expressing EGFP revealed remarkably high motility of individual endodermal epithelial cells during morphogenesis. We expect that transgenic Hydra will become important tools to dissect the molecular mechanisms of development at the base of the Metazoan tree. Sponsors: Financial support for this research was provided by the German Research Foundation [Deutsche Forschungsgemeinschaft Grants B0848/13 and SFB617.
Research institute of the Chinese Academy of Sciences, in Shanghai, established on July 3, 1999. When it was created, it was one of four basic science research institutions of China.
Software quality-assurance layer for pathway enrichment interpretation that converts enrichment term lists into context-conditioned, evidence-linked, schema-bounded claims and assigns PASS/ABSTAIN/FAIL via predefined, rule-based audit gates (stability, context validity stress tests, evidence-link integrity, and contradiction checks), producing decision-grade reports with audit logs. The LLM is confined to proposal-only steps; final decisions are mechanical and reproducible.
Tools for the integration of data from various sources (public and confidential), for the generation and validation of computer models for toxic effects, libraries for the development and seamless integration of new algorithms, and scientifically sound validation routines. The goal of OpenTox is to develop an interoperable predictive toxicology framework which may be used as an enabling platform for the creation of predictive toxicology applications. OpenTox is relevent for users from a variety of research areas: Toxicological and chemical experts (e.g. risk assessors, drug designers, researchers) computer model developers and algorithm developers non specialists requiring access to Predictive Toxicology models and data OpenTox applications can combine multiple web services providing users access to distributed toxicological resources including data, computer models, validation and reporting. Applications are based on use cases that satisfy user needs in predictive toxicology. OpenTox was initiated as a collaborative project involving a combination of different enterprise, university and government research groups to design and build the initial OpenTox framework. Additionally numerous organizations with industry, regulatory or expert interests are active in providing guidance and direction. The goal is to expand OpenTox as a community project enabling additional expert and user participants to be involved in developments in as timely a manner as possible. To this end, our mission is to carry out developments in an open and transparent manner from the early days of the project, and to open up discussions and development to the global community at large, who may either participate in developments or provide user perspectives. Cooperation on data standards, data integration, ontologies, integration of algorithm predictions from different methods, and testing and validation all have significant collaboration opportunities and benefits for the community. OpenTox is working to meet the requirements of the REACH legislation using alternative testing methods to contribute to the reduction of animal experiments for toxicity testing. Relevant international authorities (e.g., ECB, ECVAM, US EPA, US FDA) and industry organizations participate actively in the advisory board of the OpenTox project and provide input for the continuing development of requirement definitions and standards for data, knowledge and model exchange. OpenTox actively supports the development and validation of in silico models and algorithms by improving the interoperability between individual systems (common standards for data and model exchange), increasing the reproducibility of in silico models (by providing a quality source of structures, toxicity data and algorithms) and by providing scientifically sound and easy-to-use validation routines. OpenTox is committed to the support and integration of alternative testing methods using in vitro assay approaches, systems biology, stem cell technology, and the mining and analysis of human epidemiological data. Hence the framework design must take into account extensibility to satisfy a broad range of scientific developments and use cases.
A portal that provides a province-wide, population-based cancer control program for the residents of British Columbia and the Yukon. The BC Cancer Agency''s mandate covers the spectrum of cancer care, from prevention and screening, to diagnosis, treatment, and through to rehabilitation. The BC Cancer Agency''s mandate is driven by a three-fold mission: 1. To reduce the incidence of cancer; 2. To reduce the mortality rate of people with cancer; 3. To improve the quality of life of people living with cancer. This mission drives everything we do, including providing screening, diagnosis and care, setting treatment standards, and conducting research into causes of, and cures for, cancer. The BC Cancer Agency operates five regional cancer centers, providing assessment and diagnostic services, chemotherapy, radiation therapy, and supportive care. Each of the BC Cancer Agency''s centers delivers cancer treatment based on provincial standards and guidelines established by the Agency. We work in partnership with communities to provide a network of chemotherapy clinics so patients can receive care closer to home. Research is an essential part of the BC Cancer Agency''s mission to not only find the causes of cancer, but to find better treatments for prolonged life and better quality of life. With direct links between the BC Cancer Agency''s physicians and researchers at our five centers, the Deeley Research Centre (located in Victoria) and the BC Cancer Agency''s Research Centre (located in Vancouver), we can quickly translate new discoveries into clinical applications. The BC Cancer Agency''s Research Centre includes eight specialty laboratories including the Genome Sciences Centre, and the Terry Fox Laboratory. The BC Cancer Foundation raises funds for cancer research and enhancements to care at the BC Cancer Agency.
Software package to provide interface for the most frequent tasks of survival analysis, with focus on the needs of clinical oncology. The syntax follows the tidyverse philosophy and is made to be used in a pipeline.
Consortium to comprehensively map long-distance brain connections and their variability. It is acquiring data and developing analysis pipelines for several modalities of neuroimaging data plus behavioral and genetic data from healthy adults.
The Gregor Mendel Institute of Molecular Plant Biology (GMI) was founded by the Austrian Academy of Sciences in 2000 in the form of a company to promote research excellence within the field of plant molecular biology. It is the only international centre for basic plant research in Austria. The GMI is located at the Vienna Biocenter Campus within the purpose-built Austrian Academy of Sciences Life Sciences Center Vienna, completed in January 2006. The Vienna Biocenter Campus, which encompasses both independent and academic research institutes as well as biotechnology companies, provides an ideal environment for the GMI. Neighbouring institutes include the Research Institute of Molecular Pathology (IMP), the Institute of Molecular Biotechnology (IMBA), as well as the Max F. Perutz Laboratories of the University of Vienna and of the Medical University of Vienna. Research at the GMI is curiosity driven and covers many aspects of molecular genetics, from basic mechanisms of epigenetics to population genetics. Arabidopsis thaliana is used as the primary model organism, and research groups are evaluated annually by an international external Scientific Advisory Board. The working language of the GMI is English. Research at the GMI is carried out by independent research groups, led either by senior group leaders with contracts of unlimited duration, or junior group leaders with temporary (5 3 years) appointments. GMI''s research activities are supported by its administration and a platform consisting of the GMI''s own services, including state-of-the-art plant growth facilities, as well as joint services with the Research Institute of Molecular Pathology and the Institute of Molecular Biotechnology Funding Our employees are expected to apply for grants and additional financial support from various external national and international funding bodies. The list below provides an overview of the funding opportunities that could be relevant for GMI members. The Frderassistent of the FFG (in German) or the Frderkompass of the Federal Ministry of Transport, Innovation and Technology (in German) can also be used to find appropriate funding.
Specialized research and technical core at the Université de Technologie de Compiègne (UTC), specifically within the BMBI (Bio-Mechanics and Bio-Engineering) CNRS lab, dedicated to the engineering of biological systems. Designed to support training, research, and development activities in the healthcare field, acting as a bridge between engineering and biology. Integrates complementary technological facilities dedicated to the engineering, production, culture, and characterization of biological systems, ranging from simple models to complex structures. It brings together expertise covering the entire experimental workflow, from the design and fabrication of technological devices and biological supports to their cultivation, monitoring, and functional analysis.
Community wiki for an open-content textbooks collection that anyone can improve or add to, start new books, and join project-related discussions in the reading rooms. Contributors maintain the property rights to their contributions, while the Creative Commons Attribution-ShareAlike License and the GNU Free Documentation License makes sure that the submitted version and its derivative works will always remain freely distributable and reproducible. Categories include: Computing, Engineering, Humanities, Languages, Mathematics, Miscellaneous, Science, Social sciences, All subjects. Wikibooks has two sub-projects; Wikijunior which is aimed at children and the Cookbook which is a collection of recipes and culinary topics. * 2,440 books with 40,746 pages (March 2012)
http://www.cdc.gov/niosh/oep/funding.html
Software C++ API for acquiring neurophysiological data directly into the NWB (Neurodata Without Borders) format. Our goal is to provide a lightweight API to integrate with existing acquisition systems.
genes2mind is a tool for rapid exploratory analysis of psychotropic drug-induced gene expression in the brain. We present here an open resource containing comparison of effects of various classes of psychotropic drugs on transcriptional alterations of ~20,000 genes in the mouse brain (C57BL/6J). Data stored in the database include raw gene expression values as well as results of drug comparison. * Genomic Signature Identification section allows for the identification of drug-specific genomic signatures. * Genomic Signature Analysis section allows for further inspection and visualization of the signatures using multidimensional data analysis (PCA), co-expression analysis and heatmaps. * Single Gene Inspection allows for brief review of expression of specific candidate genes using barplots.
The Okinawa Institute of Science and Technology Promotion Corporation (OIST PC) was established in September 2005 to conduct best in the world research and education in science and technology, and to prepare the ground for the creation of a new graduate University in Okinawa. Our concept was to grow the project out of interdisciplinary research in areas that integrate components from biology, physics, chemistry, mathematics and computation science. We have done so by recruiting researchers in Neurosciences, Molecular Sciences and Mathematical and Computational Biology, and we have recently added Environmental Science as a new focus. OIST P.C. is unique in that we are a Japanese government-funded agency, but maintain independence in developing and conducting our research and academic programs. We drive towards excellence, and we are committed to developing programs to enable outstanding researchers to be given the opportunity to conduct independent research and to excel in their chosen research topics, as well as extending to talented students the chance to access a world-class education program in Okinawa. At a time when worldwide support for research is increasingly risk-averse and obtaining funding places an ever-growing burden on faculty, OIST promotes innovative research in a highly facilitating and supportive environment. In addition to seminars and workshops, Okinawa Institute of Science and Technology Promotion Corporation (OIST) provides students from Japanese and overseas universities with education and research opportunities through a system of collaborative graduate programs and placements. Prior to the opening of the graduate university in FY 2012, these allow students to receive research guidance in a broad range of topics from Principal Investigators of research laboratories at OIST (units) through two different student research assistantships.
Core provides multi-modal imaging services for academic investigators, national collaborators, and industrial partners.It facilitates longitudinal studies in animal models using MRI, PET, CT, and ultrasound, offering services such as image acquisition, analysis, and consultations for research, therapy assessment, and disease progression tracking.