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Integrated Clinical Trials is a virtual database currently indexing clinical trials from: EU Clinical Trials Register and ClinicalTrials.gov.
(last updated: Nov 28, 2022)
Clinical Trials Information| Database | Title | Recruitment | Conditions | Intervention | Sponsored By | Gender | |||||
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Clinicaltrials.gov | SWOG-8819 Collecting, Analyzing, and Storing Tissue Samples From Patients With Non-Hodgkin's Lymphoma | Completed | Lymphoma | Other, Other, Other - biologic sample preservation procedure, immunohistochemistry staining method, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 16 Years - N/A | Observational | RATIONALE: Collecting and storing samples of tissue from patients with cancer to study in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer. It may also help doctors learn how patients respond to treatment. PURPOSE: This laboratory study is collecting, analyzing, and storing tissue samples from patients with non-Hodgkin's lymphoma. | |||
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Clinicaltrials.gov | S9031-S9126-S9333-S9500-A, Studying Bone Marrow and Blood Samples From Patients With Acute Myeloid Leukemia | Completed | Leukemia | Genetic, Genetic, Genetic, Genetic, Genetic, Other - DNA analysis, DNA methylation analysis, RNA analysis, gene expression analysis, reverse transcriptase-polymerase chain reaction, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 18 Years - N/A | Observational | RATIONALE: Studying samples of bone marrow and blood in the laboratory from patients with cancer may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is looking at bone marrow and blood samples from patients with acute myeloid leukemia. | |||
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Clinicaltrials.gov | SWOG-9023, DNA Analysis of Tumor Tissue From Patients With Metastatic Kidney Cancer | Completed | Kidney Cancer | Genetic, Genetic, Genetic, Genetic, Other, Other - DNA ploidy analysis, DNA stability analysis, chromosomal translocation analysis, cytogenetic analysis, flow cytometry, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | N/A - N/A | Observational | RATIONALE: DNA analysis of tumor tissue may help doctors predict how well patients will respond to treatment. PURPOSE: This laboratory study is analyzing the DNA in tumor tissue from patients with metastatic kidney cancer. | |||
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Clinicaltrials.gov | S8809-S9800-S9911TM- Biological Markers in Patients With Follicular Lymphoma Treated on Clinical Trial SWOG-8809, SWOG-9800, or SWOG-9911 | Completed | Lymphoma | Genetic, Other, Other - microarray analysis, immunohistochemistry staining method, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 16 Years - 120 Years | Observational | RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may also help doctors predict how patients respond to treatment. PURPOSE: This laboratory study is examining biological markers in patients with follicular lymphoma treated on clinical trial SWOG-8809, SWOG-9800, or SWOG-9911. | |||
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Clinicaltrials.gov | S9031-S9333-S0112-S0301-A Biomarkers Associated With Response to Cytarabine in Samples From Older Patients With Acute Myeloid Leukemia | Completed | Leukemia | Genetic, Genetic, Other, Other - gene expression analysis, proteomic profiling, flow cytometry, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 56 Years - N/A | Observational | RATIONALE: Studying samples of blood and tissue from patients with cancer treated with cytarabine in the laboratory may help doctors learn more about the effects of cytarabine on cells. It may also help doctors understand how well patients respond to treatment. PURPOSE: This research trial studies biomarkers associated with response to cytarabine in samples from older patients with acute myeloid leukemia. | |||
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Clinicaltrials.gov | S8516-S8736-S9125-S9240 Research Study of Genes in Tissue Samples From Patients With B-cell Non-Hodgkin Lymphoma | Completed | Lymphoma | Genetic, Other, Other - polymorphism analysis, laboratory biomarker analysis, pharmacogenomic studies | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 18 Years - N/A | Observational | RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is looking at genes in tissue samples from patients with B-cell non-Hodgkin lymphoma. | |||
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Clinicaltrials.gov | S0106A, Biomarkers in Samples From Patients With Newly Diagnosed Acute Myeloid Leukemia Treated With Cytarabine-Based Chemotherapy | Completed | Leukemia | Genetic, Other, Other - proteomic profiling, flow cytometry, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 18 Years - 60 Years | Observational | RATIONALE: Studying samples of bone marrow and blood from patients with cancer in the laboratory may help doctors predict how well patients will respond to treatment. PURPOSE: This research study studies biomarkers in samples from patients with newly diagnosed acute myeloid leukemia treated with cytarabine-based chemotherapy. | |||
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Clinicaltrials.gov | S9704-S0014-S0313A Studying Genes in Samples From Patients With Limited or Advanced Diffuse Large B-Cell Lymphoma | Completed | Lymphoma | Genetic, Genetic, Other, Other - RNA analysis, gene expression analysis, immunohistochemistry staining method, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 18 Years - N/A | Observational | RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may also help doctors find better ways to treat cancer. PURPOSE: This research trial studies genes in samples from patients with limited and advanced diffuse large B-cell lymphoma. | |||
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Clinicaltrials.gov | S8600-S9031-S9333-A, Study of DNA in Samples From Patients With Acute Myeloid Leukemia | Completed | Leukemia | Genetic, Genetic, Genetic, Other, Other - DNA methylation analysis, gene expression analysis, microarray analysis, laboratory biomarker analysis, medical chart review | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 18 Years - N/A | Observational | RATIONALE: Studying samples of blood and bone marrow from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients respond to treatment. PURPOSE: This research trial studies DNA in samples from patients with acute myeloid leukemia. | |||
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Clinicaltrials.gov | S9313B Study of Tumor Tissue Samples From Women With Early-Stage Breast Cancer Enrolled on Clinical Trial SWOG-9313 | Completed | Breast Cancer | Other, Other - immunohistochemistry staining method, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | Female | 18 Years - N/A | Observational | RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients enrolled on clinical trial SWOG-9313 will respond to doxorubicin and cyclophosphamide. PURPOSE: This laboratory study is looking at tumor tissue samples from women with early-stage breast cancer enrolled on clinical trial SWOG-9313. | ||
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Clinicaltrials.gov | S8809-S9800-S9911-S9704-A Study of Blood and Tissue Samples From Patients With Follicular Lymphoma Treated With Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone | Completed | Lymphoma | Genetic, Genetic, Genetic, Other - DNA analysis, polymerase chain reaction, polymorphism analysis, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 18 Years - N/A | Observational | RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment. PURPOSE: This research study is looking at blood and tissue samples from patients with follicular lymphoma treated with rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine, and prednisone. | |||
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Clinicaltrials.gov | S0307A, Long-Term Bone Quality in Women With Breast Cancer Enrolled on Clinical Trial SWOG-S0307 | Withdrawn | Breast Cancer | Drug, Drug, Drug, Drug, Drug, Other, Procedure, Procedure, Procedure - clodronate disodium, demeclocycline hydrochloride, ibandronate sodium, tetracycline hydrochloride, zoledronic acid, laboratory biomarker analysis, adjuvant therapy, computed tomography, dual x-ray absorptiometry | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | Female | 18 Years - N/A | Observational | RATIONALE: Gathering information over time from imaging and laboratory tests of women receiving bisphosphonates for breast cancer may help doctors learn more about long-term bone quality and plan the best treatment. Tetracycline hydrochloride and demeclocycline hydrochloride can mark the new growth of the bone, so it may be seen better under a microscope. PURPOSE: This clinical trial is studying long-term bone quality in women with breast cancer enrolled on clinical trial SWOG-S0307. | ||
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Clinicaltrials.gov | S9031-9333-0106-0112-A Study of Biomarkers in Samples From Patients With Acute Myeloid Leukemia Treated With Standard Chemotherapy With or Without Gemtuzumab Ozogamicin | Completed | Leukemia | Genetic, Genetic, Genetic, Genetic, Genetic, Other - DNA analysis, RNA analysis, gene expression analysis, mutation analysis, polymerase chain reaction, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 18 Years - 88 Years | Observational | RATIONALE: Studying samples of bone marrow and blood from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. PURPOSE: This research trial studies biomarkers in samples from patients with acute myeloid leukemia treated with standard chemotherapy with or without gemtuzumab ozogamicin. | |||
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Clinicaltrials.gov | S9031-S9126-S9333-S9500-B Biomarker Expression in Patients With Acute Myeloid Leukemia | Completed | Leukemia | Genetic, Genetic, Genetic, Genetic, Genetic, Other - DNA analysis, RNA analysis, mutation analysis, polymerase chain reaction, polymorphism analysis, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 18 Years - N/A | Observational | RATIONALE: Studying samples of bone marrow from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is looking at biomarker expression in bone marrow samples from patients with acute myeloid leukemia. | |||
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Clinicaltrials.gov | S0120, Studying Blood and Bone Marrow Samples From Patients With Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, or Plasmacytoma | Completed | Multiple Myeloma, Plasma Cell Myeloma, Precancerous Condition | Genetic, Genetic, Other, Other - cytogenetic analysis, microarray analysis, biologic sample preservation procedure, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | N/A - N/A | Observational | RATIONALE: Studying samples of blood and bone marrow in the laboratory from patients with monoclonal gammopathy of undetermined significance, multiple myeloma, or plasmacytoma may help doctors learn more about changes that occur in DNA and identify biomarkers related to these diseases. It may also help doctors predict how patients will respond to treatment. PURPOSE: This research study is looking at blood and bone marrow samples from patients with monoclonal gammopathy of undetermined significance, multiple myeloma, or plasmacytoma. | |||
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Clinicaltrials.gov | S9333A Study of Blood and Bone Marrow Samples From Patients With Previously Untreated Primary Acute Myeloid Leukemia | Completed | Leukemia | Genetic, Genetic, Other, Other - polyacrylamide gel electrophoresis, western blotting, immunologic technique, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 56 Years - N/A | Observational | RATIONALE: Studying samples of blood and bone marrow from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is looking at blood and bone marrow samples from patients with previously untreated primary acute myeloid leukemia. | |||
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Clinicaltrials.gov | S0106B Studying Bone Marrow Samples From Women With Acute Myeloid Leukemia | Completed | Leukemia | Genetic, Other, Other, Other, Other - gene expression analysis, flow cytometry, fluorescence activated cell sorting, laboratory biomarker analysis, medical chart review | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | Female | 18 Years - N/A | Observational | RATIONALE: Studying samples of bone marrow from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. PURPOSE: This research trial studies bone marrow samples from women with acute myeloid leukemia. | ||
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Clinicaltrials.gov | S9313A Protein Expression Analysis of Breast Cancer Tissue Microarrays From Clinical Trial SWOG-9313 | Completed | Breast Cancer | Genetic, Genetic, Other, Other - gene expression analysis, protein expression analysis, fluorescent antibody technique, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | Female | 18 Years - N/A | Observational | RATIONALE: Studying the proteins expressed in tumor tissue samples in the laboratory from patients with cancer may help doctors learn more about biomarkers related to cancer. It may also help doctors predict how patients respond to treatment. PURPOSE: This laboratory study is looking at protein expression in predicting response to treatment using tumor tissue samples from women with stage I, stage II, or stage IIIA breast cancer treated on clinical trial SWOG-9313. | ||
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Clinicaltrials.gov | S0424 - Carcinogens in Lung Tissue From Smokers (Closed to Entry as of 7/15/07) and Non-Smokers With Newly Diagnosed Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer | Completed | Lung Cancer | Genetic, Genetic, Genetic, Genetic, Genetic, Other, Other, Other, Other, Other, Procedure - chromogenic in situ hybridization, gene expression analysis, mutation analysis, polymerase chain reaction, polymorphism analysis, fluorescent antibody technique, immunohistochemistry staining method, laboratory biomarker analysis, matrix-assisted laser desorption/ionization time of flight mass spectrometry, study of socioeconomic and demographic variables, study of high risk factors | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | 18 Years - 120 Years | Observational | RATIONALE: Studying samples of blood and tissue from smokers (closed to entry as of 7/15/07) and non-smokers with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors learn more about risk factors for lung cancer and may help the study of cancer in the future. PURPOSE: This clinical trial is studying carcinogens in lung tissue from smokers (closed to entry as of 7/15/07) and non-smokers with newly diagnosed stage I, stage II, or stage III non-small cell lung cancer. | |||
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Clinicaltrials.gov | S9346A Blood Samples From Patients With Metastatic Prostate Cancer Previously Treated With Bicalutamide and Goserelin | Completed | Prostate Cancer | Genetic, Genetic, Other - gene expression analysis, polymorphism analysis, laboratory biomarker analysis | Southwest Oncology Group, National Cancer Institute (NCI), Other, NIH | Male | 18 Years - 120 Years | Observational | RATIONALE: Studying samples of blood in the laboratory from patients with cancer may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment. PURPOSE: This research study is studying blood samples from patients with metastatic prostate cancer previously treated with bicalutamide and goserelin. |
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