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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.med.unc.edu/marsicolunginstitute/core-facilities/histology-core
Core that provides light microscopy services like prosection, tissue fixation, processing, embedding, sectioning, staining and cover slipping of paraffin, frozen and soft plastic tissue sections, as well as specialized and routine fixation, tissues processing, ultramicrotomy, staining, photomicrograph production, and analysis.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Histology Core (RRID:SCR_015385) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/mousemodelscore
Core that provides support and expertise for mouse colony maintenance, breeding strategies, mouse lung phenotyping protocols, and submission of live-animal applications to maintain compliance with IACUC guidelines.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Mouse Models Core (RRID:SCR_015389) Copy
https://www.med.unc.edu/marsicolunginstitute
Research team dedicated to finding a cure for cystic fibrosis lung disease. This team utilizes ion transport physiology, transgenic and gene-targeted mouse models, Phase I clinical trials, and more to research this cause.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center (RRID:SCR_015388) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/pre-clinical-core
Core whose objectives include evaluation of pre-clinical drug candidates in vitro, pre-clinical drug candidates ex vivo, and pre-clinical drug candidates in vivo.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Pre-Clinical Core (RRID:SCR_015387) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/molecular-biology-core
Core facility that provides expertise, equipment, training, and reagents to serve the molecular biology needs for cystic fibrosis research.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Molecular Biology Core (RRID:SCR_015384) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/michael-hooker-microscopy-core
Core that provides advanced digital light microscopy, image processing and analysis resources for users from the UNC Chapel Hill campus. It also offers instrumentation and instruction to enable users to acquire, process and analyze images from a wide variety of sample types.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Michael Hooker Microscopy Core Facility (RRID:SCR_015390) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/ClinicalTranslationalCore
Core whose services include biospecimen collection and storage, development of lung imaging outcomes, imaging training, and biostatical analysis.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Clinical Translational Core (RRID:SCR_015391) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/TissueProcurmentandCellCultureCore
Core that provides standardized cell cultures for cystic fibrosis research, notably normal, cystic fibrosis and disease control cells, tissues and fluids. Its functions include tissue procurement, airway epithelial cell isolation and culture, collecting airway surface liquid from in vivo and in vitro samples, genetic manipulation of cell cultures, creating and characterizing novel cell lines, and translation of technology and reagents to the greater cystic fibrosis research community.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Tissue Procurement and Cell Culture Core (RRID:SCR_015394) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/mucuscore
Core that provides a service to quantify the concentration of given mucus samples for both total mucus concentration and the absolute relative contributions of each secreted mucin. It also provides quantitation of extracellular DNA. The mucus biphysics subcore component, provides core users with information on the biophysical properties of the mucus layer and its interaction with the cell surface.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Mucus and Mucin Biochemistry and Biophysics Core (RRID:SCR_015393) Copy
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