We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
List of proteins commonly found in proteomics experiments that are present either by accident or through unavoidable contamination of protein samples. List is based on analysis of current version of GPMDB, as well as suggestions by users. Current version of cRAP in FASTA format can be obtained from the GPM FTP site.
Core provides advanced mass-spectrometric instrumentation and for both proteomics and metabolomic experiments. Performs qualitative and quantitative analysis of proteins and post-translationally modified peptides and both targeted and untargeted LC/GC-MS based metabolomics.
The Parkinson''s UK Brain Bank is the UK''s largest brain bank dedicated to Parkinson''s. We collect the brain, spinal cord and a sample of cerebrospinal fluid from people with and without Parkinson''s after death. We supply tissue to researchers investigating Parkinson''s in the UK and around the world who are working towards a cure for Parkinson''s. Vital research relies upon the generosity of donors and their families who make the vital gift of brain donation after death. Become a brain donor and help us to find a cure and improve life for everyone affected by Parkinson''s. Just one donated brain can be used in up to 50 different research studies. The Parkinson''s UK Brain Bank is currently supporting more than 100 research projects. And we have more than 6,000 registered potential donors. Our tissue is: * free - unlike other banks, we don''t charge researchers for tissue * high quality - we collect most tissue within 24 hours of death * fast - we aim to supply tissue within 4 weeks * neuropathologically diagnosed - according to the latest criteria And we can: * issue ethical approval for projects that fit our research criteria - saving you time * provide tissue suitable for all modern research techniques - including snap frozen and fixed samples * offer expertise and training to researchers working with human tissue We don''t just supply brain tissue. We also know a lot about our donors, which means we can provide tissue to match your project. Donated tissue come with clinical notes from the healthcare team. And every donor provides details of their symptoms, medical history, lifestyle and medications. This makes our offer of tissue and information unique.
Medical image repository to store medical research data.
Core is a multi-user facility located on the 4th floor in the Translational Research Building (TRB) at A4-132. Histology facility offers services for processing tissue samples, automated equipment for tissue processing, paraffin embedding, micro-sectioning, and staining. Our technicians offer consultation, experimental design, and troubleshooting and work closely with researchers to get the most optimal tissue sections tailored to each project. The facility also provides training on the microtome and paraffin embedder to allow flexibility in workflow.
Ontology of Computer retrieval of Information on Scientific Projects (CRISP).
Free online archive and distribution server for complete but unpublished manuscripts in the medical, clinical, and related health sciences. Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health related behavior and should not be reported in news media as established information. Research articles, systematic reviews and meta analyses, clinical research design protocols and data articles may be posted.
Core provides services in Assay Development, Assays Experimental Design, Immune Monitoring, Cytokine Assays, ELISA, multiplex Flow based and Luminex based Bead Arrays, Project Based Flow Cytometry and Data Analysis.
Podcasts (Audio and video files over the internet) form the Translational Genomics Research Institute.
Develops research projects in pediatric genetics and provides essential services in molecular biology and genetics to Nemours clinicians and research staff and to affiliates researchers of University of Delaware and Thomas Jefferson University. Resource for staff of Alfred I. duPont Hospital for Children, Nemours affiliates, COBRE / INBRE investigators and outside customers. Offers expertise in molecular genetics and genomics. Operates according to policies set forth by federal CLIA standards.Services provided include Ion Torrent PGM Next Generation Sequencing, QuantStudio (QS) 3D Digital PCR, Cell Line Authentication, Nucleic Acid Quality Number (AATI Fragment Analyzer),Genotyping including Allelic Discrimination Probes (SNP Real-Time PCR), Affymetrix Microarray (CNV CytoScan, SNP arrays), Fragment Analysis (Capillary Electrophoresis up to 1200 bp), DNA Sequencing (Sanger Sequencing), Expression Analysis including Affymetrix Microarray (global gene expression, transcriptome assays), Pathway-focused Real-Time qPCR (mRNA and miRNA). Shared Instrumentation including Beckman Biomek 3000 Liquid Handler, NanoDrop 2000c, ABI7900 384-well Real-Time Genetic Analyzer, PCR Tamer, Thermocyclers.
Software R package to reduce and visualize Gene Ontology terms. Used for interpreting lists of Gene Ontology terms.
A software library for analyzing DNase-seq data.
Dataset of scholarly articles, including full text, on COVID-19, SARS-CoV-2, and related coronaviruses. Machine readable resource provided to enable application of natural language processing and other AI techniques. Open resource for global research community. Updated weekly as new research is published in peer-reviewed publications and archival services like bioRxiv, medRxiv, and others.
Software R package for tidying output of statistical models.
The TIGR database is a collection of plant transcript sequences. Transcript assemblies are searchable using BLAST and accession number. The construction of plant transcript assemblies (TAs) is similar to the TIGR gene indices. The sequences that are used to build the plant TAs are expressed transcripts collected from dbEST (ESTs) and the NCBI GenBank nucleotide database (full length and partial cDNAs). "Virtual" transcript sequences derived from whole genome annotation projects are not included. All plant species for which more than 1,000 ESTs or cDNA sequences are available are included in this project. TAs are clustered and assembled using the TGICL tool (Pertea et al., 2003), Megablast (Zhang et al., 2000) and the CAP3 assembler (Huang and Madan, 1999). TGICL is a wrapper script which invokes Megablast and CAP3. Sequences are initially clustered based on an all-against-all comparisons using Megablast. The initial clusters are assembled to generate consensus sequences using CAP3. Assembly criteria include a 50 bp minimum match, 95% minimum identity in the overlap region and 20 bp maximum unmatched overhangs. Any EST/cDNA sequences that are not assembled into TAs are included as singletons. All singletons retain their GenBank accession numbers as identifiers. Plant TA identifiers are of the form TAnumber_taxonID, where number is a unique numerical identifier of the transcript assembly and taxonID represents the NCBI taxon id. In order to provide annotation for the TAs, each TA/singleton was aligned to the UniProt Uniref database. For release 1 TAs, a masked version of the Uniref90 database was used. For release 2 and onwards, a masked version of the UniRef100 database is used. Alignments were required to have at least 20% identity and 20% coverage. The annotation for the protein with the best alignment to each TA or singleton was used as the annotation for that sequence. Additionally, the relative orientation of each TA/singleton to the best matching protein sequence was used to determine the orientation of each TA/singleton. Some sequences did not have alignments to the protein database that met our quality criteria, and those sequences have neither annotation nor orientation assignments. The release number for the plant TAs refers to the release version for a particular species. For the initial build, all TA sets are of version 1. Subsequent TA updates for new releases will be carried out when the percentage increase of the EST and cDNA counts exceeds 10% of the previous release and when the increase contains more than 1,000 new sequences. New releases will also include additional plant species with more than 1,000 EST or cDNA sequences that have become publicly available.
Web page created by American Diabetes Association. Contains resources and information about COVID-19 for diabetes professionals and patients. ADA also provides online forum, webinar series and podcast. Online forum to exchange questions, answers, and best practices with leading clinicians from diabetes community. All ADA members can contribute, and any interested health professional can read forum and responses.
CyTOF Core shares equipment and expertise with researchers. Provided instruments include: Helios CyTOF System (Suspension CyTOF), Hyperion CyTOF System (Imaging CyTOF), Attune Flow Cytometer, ÄKTA Pure FPLC, NanoDrop 2000c Spectrophotometer. Offered services include Human immune profiling panel for 29-color analysis of cells in suspension; Mouse immune profiling panel for 16-color analysis of cells in suspension; Custom CyTOF antibody conjugation; Data acquisition of cells in suspension using Helios CyTOF; Image acquisition of tissue sections using Hyperion CyTOF.
Resource Discovery System is a web-accessible and searchable inventory of biomedical research resources. Powered by the Resource Discovery System (RDS) that includes a standards-based informatics infrastructure * Biositemaps Information Model * Biomedical Resource Ontology Extensions * Web Services distributed web-accessible inventory framework * Biositemap Resource Editor * Resource Discovery System Source code and project documentation to be made available on an open-source basis. Contributing institutions: University of Pittsburgh, University of Michigan, Stanford University, Oregon Health & Science University, University of Texas Houston. Duke University, Emory University, University of California Davis, University of California San Diego, National Institutes of Health, Inventory Resources Working Group Members
Software tool as free color blindness simulator for Windows, Mac and Linux. Design for Color Impaired. Takes guesswork out of designing for color blindness by showing you in real time what people with common color vision impairments will see.Color Oracle is open source, available on GitHub for Mac and Windows/Java.
Research facility dedicated to the study and testing of various marine and hydrodynamic phenomena. It is part of the Department of Naval Architecture and Marine Engineering at the University of Michigan. Conducts research and experiments related to fluid dynamics, ship design, offshore engineering, and other areas relevant to marine and naval architecture.