Curator Dashboard

An executive agency of the Department of Health in the United Kingdom to protect and improve the nation''s health and well-being, and reduce health inequalities. It employs 5,500 staff, who are mostly scientists, researchers and public health professionals. They have 15 local centers and 4 regions (north of England, south of England, Midlands and east of England, and London). They work closely with public health professionals in Wales, Scotland and Northern Ireland, and internationally. Its formation came as a result of reorganization of the National Health Service (NHS) in England. It took on the role of the Health Protection Agency, the National Treatment Agency for Substance Misuse and a number of other health bodies. They are responsible for: * making the public healthier by encouraging discussions, advising government and supporting action by local government, the NHS and other people and organisations * supporting the public so they can protect and improve their own health * protecting the nation''s health through the national health protection service, and preparing for public health emergencies * sharing information and expertise with local authorities, industry and the NHS, to help them make improvements in the public''s health * researching, collecting and analyzing data to improve our understanding of health and come up with answers to public health problems * reporting on improvements in the public''s health so everyone can understand the challenge and the next steps * helping local authorities and the NHS to develop the public health system and its specialist workforce

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software to visualize and qualitatively analyze mass spectrometry data. Used to display chromatograms and spectra, detect and integrate chromatographic peaks, search mass spectral libraries, simulate mass spectra, subtract background spectra, apply scan filters, annotate plots with text and graphics, create and save layouts, view the status of various instrument parameters during data acquisition, and create a 2D or 3D representation of an analysis displaying the acquired mass/wavelength scans. Part of liquid chromatography mass spectrometry system.

• Resource
• RRID
• 4 years ago - by Anonymous

European research collaboration aimed at understanding the ways in which researchers are evaluated by their peers and by institutions, and at assessing how the science system can be improved and enhanced. This FP7 project is a cooperation among nine European research institutes with Professor Paul Wouters (CWTS ����?? Leiden University) as principal investigator.

• Resource
• SciCrunch
• 14 years ago - by Anonymous

Provides preclinical drug discovery and development services to facilitate discovery of small molecules that have potential to become cancer therapeutics.Offers expertise in drug discovery and facilitates process of uncovering novel treatments for cancer. Services include target evaluation and assay development; small molecule library preparation, screening, and curation; high throughput screening enablement; plate imaging and transfers; assay identification, development and implementation; standard and customized assays (including live cell metabolic assays, cell death assays, clonogenic assays, and alphascreen); support for hit-to-lead pharmacology (including pharmacokinetics and ADME/T); data analytics for hit-picking; investigational new drug (IND) enablement; and full pipeline project management.Offers consultation, training, educational workshops and seminars.

• Resource
• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Partially funded through Harvard Catalyst, the Clinical Research Coordinator Core is available to support and collaborate with investigators and their research teams in all phases of clinical research, providing services that include assisting with the organization, implementation and completion of clinical research studies.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Offers curated collection of high end scientific instrumentation to enable physicochemical characterization of nanoscale materials, devices, and systems under wide range of experimental conditions.Technical capabilities and expertise include surface analysis by Scanning Probe Microscopy (SPM); hydrodynamic size and surface charge analysis by Dynamic Light Scattering (DLS) and Zeta Potential (ZP) measurements; elemental and chemical analysis by Inductively Coupled Plasma Mass Spectrometry (ICP-MS).

• Resource
• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core facility that provides the following services: ES cell transfection (electroporation), Thawing/expansion of targeted ES cells, Microinjection of ES cells into blastocysts, Microinjection of DNA constructs into egg pronuclei for generating transgenic mice, Microinjection of BAC DNAs, DNA injection and microdissection, Lentiviral transgenics service, Injection of induced pluripotent stem cells for testing totipotency, Tail biopsy service, Breeding services, Mouse manipulation consultation. The Brigham & Women''s Hospital Transgenic Core Facility provides services for generating transgenic and knockout mice. Established in 1992, the BWH Core Facility has been providing gene targeting and microinjection services using state-of-the-art facilities and equipment. Dr. Lina Du, formerly a plastic surgeon in Beijing and an expert in microvascular surgery, performs both blastocyst and pronuclear injections. She has over 15 years of experience in embryo manipulation and the generation transgenic mice. The Core Facility has all of the equipment necessary for generation of transgenic mice including a Nikon Diaphot microscope equipped with Nomarski Optics and Narishige micromanipulators for microinjections, Nikon surgical microscopes for egg isolation ad transfer, a sutter needle puller and a de Fonbrune microforge. The facility maintains mice necessary for egg donors, egg recipients, and vasectomized males. This is a non-profit facility and charges are based upon anticipated mouse costs, maintenance of mice and equipment, and purchase of necessary surgical supplies and chemicals. The ES cell culture service has been offered for 6 years. Our staff carries out electroporation of targeting vectors into ES cells and provides investigators with DNA to identify ES cells carrying the desired recombination events. Then they expand the appropriate ES Cells for microinjection into blastocysts by the BWH Transgenic Core.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Offers training, assisted and unassisted use of microscopes and equipment, as well as consultations and collaborations. Support includes single particle cryo-EM, Cryo-ET, Micro-ED,simple characterization of samples in vitrified aqueous mixtures (e.g. nanoparticle size, etc.).

• Resource
• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core facility that provides the following services: Mouse breeding management, Mouse irradiation service, Technical services for laboratory animal experimentation, Veterinary care, Animal care training.

The facility provides services and resources for investigators looking to accomplish animal research objectives. This includes housing mice and rats, purchasing animals, training researchers regarding proper animal care and use, and monitoring the safety of all personnel with laboratory animal contact in conjunction with Dana-Farber?s Environmental Health and Safety and Occupational Health Services. Dana-Farber has established an Institutional Care and Use Committee (IACUC) to oversee the Institute?s animal program, facilities, and projects involving the use of animals. The IACUC serves as the approval body for all protocols involving animal research, and assists faculty, students and staff in upholding Dana-Farber?s commitment to providing the finest care and most humane utilization of laboratory animals. In addition to basic husbandry services, the ARF staff provides technical and veterinary services, mouse breeding management and mouse irradiation.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Cloud-based executable research platform for discovering and running scientific code. Code Ocean is designed to give researchers and developers a way to share, discover and run code published in academic journals and conferences. Users can upload code and data in various programming languages and link working code in a computational environment with the associated article, with Code Ocean assigning a Digital Object Identifier (DOI) to the algorithm.

• Resource
• dkNET
• 10 years ago - submitted by Maryann Martone

Core facility that provides the following services: Drosophila genome-wide and focused cell-based RNAi libraries, Custom synthesis of double-stranded RNAs for Drosophila cell-based RNAi.

The DRSC facilitates genome-wide and related cell-based screening at our state-of-the-art facility. Since our beginnings in 2003, we have successfully guided screeners through the process, including help with assay development and optimization, data and image analysis, and planning of follow-up assays. Screens performed at the DRSC have resulted in an impressive number of publications on a wide range of topics in high-profile journals.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Equipped with magnetoencephalography (MEG) scanner to detect immediate changes in electrical brain activity. Provides 306 channel whole head MEG system (TRIUX, Neo, MEGin) and 128 channels EEG amplifier.MEG helmet does coverage for whole cortex, 1220 cm2. MEG system has three measurement positions:supine, lower and upper seated. MEG system is housed within magnetic shielded room equipped with active shielding and automated helium recycler.

• Resource
• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core facility that provides the following services: DNA Synthesis Service.

The DNA Synthesis Lab serves the research community with custom oligonucleotides. The lab is capable of high-throughput standard, degenerate and modified oligo synthesis.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

THIS IS A TEST

• Resource
• NIF
• 4 years ago - by Anonymous

This Research Core provides training and research support in genotyping and quantification of nucleic acids. The Core facility has equipment needed to genotype DNA samples and to measure nucleic acid concentrations in isolation or in tissue samples.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Software R package provides integrated analysis workflow for analysis of mass spectrometry proteomics data for differential protein expression or differential enrichment.

• Resource
• RRID
• 4 years ago - by Anonymous

Tool that provides an interactive method to examine quantitative relationships between brain regions defined by different digital atlases or parcellation methods. Its current focus is for human brain imaging, though the techniques generalize to other domains. The method offers a quantitative answer to the nomenclature problem in neuroscience by comparing brain parts on the basis of their geometrical definitions rather than on the basis of name alone. Thus far these tools have been used to quantitatively compare eight distinct parcellations of the International Consortium for Brain Mapping (ICBM) single-subject template brain, each created using existing atlasing methods. This resources provides measures of global and regional similarity, and offers visualization techniques that allow users to quickly identify the correspondences (or lack of correspondences) between regions defined by different atlases.

• Resource
• SciCrunch
• 14 years ago - by Anonymous

Core to apply advanced molecular genetic techniques in rodent models of physiology and disease. Generates novel mutant mouse strains by using gene targeting in embryonic stem cells (ESCs) and by developing novel methods of modifying rodent genomes and assaying genetically modified cells in vivo.Offers sperm and embryo cryopreservation and storage technologies for strain preservation and recovery.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

One of the country''s leading procurement organizations and is just one of eight nationwide to house organ, tissue, and eye donation in one location. With the addition of community blood banking services in the summer of 2007, Upstate New York Transplant Services became the only organization nationwide to offer such services in conjunction with organ, tissue, and eye donation. Licensed by the NY State Dept. of Health, FDA-Registered Accredited by the Eye Bank Association of America (EBAA) and American Association of Tissue Banks (AATB)

• Resource
• SciCrunch
• 16 years ago - by Anonymous

Software R package for unbiased cell type recognition of scRNA-seq data. Performs unbiased cell type recognition from single-cell RNA sequencing data, by leveraging reference transcriptomic datasets of pure cell types to infer cell of origin of each single cell independently.

• Resource
• RRID
• 4 years ago - by Anonymous