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Established in 1980, the Life Extension Foundation is a nonprofit organization, whose long-range goal is to radically extend the healthy human lifespan by discovering scientific methods to control aging and eradicate disease. The largest organization of its kind in the world, the Life Extension Foundation has always been at the forefront of discovering new scientific breakthroughs for use in developing novel disease prevention and treatment protocols to improve the quality and length of human life. Through its private funding of research programs aimed at identifying and developing new therapies to slow and even reverse the aging process, the Life Extension Foundation seeks to reduce, and ultimately eliminate, such age-related killers as heart disease, stroke, cancer and Alzheimer''s disease. Long-time members are keenly aware of the scientific research that Life Extension Foundation funds to develop validated methods to slow and reverse the aging process. Less known is Life Extension''s multi-prong program to develop safer and more effective cancer therapies. One reason we focus so heavily on cancer research is that this dreaded disease represents a roadblock in our ability to develop effective means to combat aging.

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• SciCrunch
• 16 years ago - by Anonymous

Provides NGS services for research and clinical samples in CLIP and CAP accredited laboratory.Services include consultation, sample processing, sequencing and data analysis , as well as interpretation and reporting.Service support for genomics based applications including experimental design, bioinformatics, development of novel assays, grant writing and manuscript preparation. We are experienced in broad range of biological disciplines including basic biology, infectious diseases, cancer, neurobiology, immunology and clinical research. Clinical Genomics lab has extensive experience in molecular diagnostics and clinical research, and specializes in clinical biomarker discovery, validation and diagnostic test development.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Software R package for computation of adjusted rand-index and other such scores. Used for efficient computations of standard clustering comparison measures.

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• RRID
• 2 months ago - submitted by Zhenhao Shi

The Museum of Comparative Anthropogeny (MOCA) is a collection of comparative information regarding humans and our closest evolutionary cousins (chimpanzees, bonobos, gorillas and orangutans i.e, great apes), with an emphasis on uniquely human features. MOCA is organized by Domains, each grouping Topics by areas of interest and scientific discipline. Each topic entry will eventually cover existing information about a particular difference (alleged or documented) between humans and non-human hominids. Comparisons of these non-human hominids with humans are difficult, as so little is known about their phenotypic features (phenomes), in contrast to humans. Ethical, fiscal and practical issues also limit collection of further information about great apes. MOCA attempts to collect existing information about human-specific differences from great apes, currently scattered in the literature. Having such information in one location could lead to new insights and multi-disciplinary interactions, and to ethically-sound studies to explain differences, and uniquely human specializations. MOCA is not targeted at experts in specific disciplines, but rather aims to communicate basic information to a broad audience of scientists from many backgrounds, and to the interested lay public. MOCA includes not only aspects wherein there are known or apparent differences between humans and great apes, but additionally, topics for which popular wisdom about claimed or assumed differences is not entirely correct. It is for all these reasons that MOCA is called a Museum, and not an Encyclopedia or Database.

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• SciCrunch
• 16 years ago - by Anonymous

Software tool for prediction of lysine acetyltransferase specific modification sites from protein sequences.

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• RRID-Legacy
• 5 years ago - submitted by Jiayi Wan

Core offers guidance, collaboration, and services in animal models and in vivo imaging for cancer research. Provided services include consultation on experimental design, patient-derived xenograft implantation services, treatment and tumor monitoring, in vivo imaging, humanized mouse models, and training in support of cancer research employing animal models.

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• RRID
• 2 months ago - by Anonymous

Dictyostelium discoideum is a great organism to use to teach cellular biology. It exhibits very interesting behaviors, such as chemotaxis and phagocytosis, that can readily be studied in standard laboratories without the need for expensive equipment. Lists of labs being used in real courses settings and all necessary information for performing those experiments are provided. Major headings: * Dictyostelium cell biology course, by Dr. David Knecht, University of Connecticut * Dictyostelium cell biology, by Dr. Derrick Brazill, Hunter College, New York * Report on the number of cells in a slug, contributed by John Bonner * Practical on chemotaxis, by Dr. Thierry Soldati, University of Geneva * Comments from Researchers * References suggested by contributors

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• SciCrunch
• 16 years ago - by Anonymous

Software annotation tool for audio and video recordings. Annotation can be sentence, word or gloss, comment, translation or description of any feature observed in media. Annotations can be created on multiple layers. Tiers can be hierarchically interconnected. Annotation can either be time-aligned to media or it can refer to other existing annotations. Content of annotations consists of Unicode text and annotation documents are stored in XML format (EAF).

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• RRID-Legacy
• 5 years ago - by Anonymous

Core for advanced materials characterization, micro/nanoscale manufacturing, and bioengineering research. NERCF provides open access to more than 20 state-of-the-art research instruments, technical consultation, user training, and collaborative research support for investigators from academia, government laboratories, industry, and external institutions. Major capabilities include scanning electron microscopy, focused ion beam, X-ray computed tomography, metal additive manufacturing, atomic force microscopy, nano-IR spectroscopy, optical profilometry, and mechanical characterization. By integrating advanced manufacturing with multimodal characterization, NERCF supports interdisciplinary research, workforce development, and innovation across Nebraska and beyond.

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• SciCrunch
• 2 months ago - submitted by Edyta Vieth

Evaluates disease-causing potential of sequence alterations.

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• SciCrunch
• 13 years ago - by Anonymous

StemCore Laboratories is a high-throughput genomics facility within the Ottawa Hospital Research Institute (OHRI). Core is capable of facilitating large-scale scientific research and biotechnology projects.Provides infrastructure for genomics, bioinformatics, and proteomics.

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• SciCrunch
• 14 years ago - by Anonymous

Public university located in College Station, Texas, USA.

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• SciCrunch
• 17 years ago - submitted by Andrea Stagg

An algorithm that allows researchers to identify transcript factor binding sites from paired-end sequencing reads. SIPeS uses a dynamic baseline directly through the piling up of fragments to effectively find peaks, overcoming the disadvantage of estimating the average length of DNA fragments from singled-end sequencing achieving more powerful prediction binding sites with high sensitivity and specificity.

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• SciCrunch
• 13 years ago - by Anonymous

Facility provides access to high performance computing environment, BioHPC, which includes both hosted hardware and shared machines. Provides consulting and collaborations for Bioinformatics analysis and workflows.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Core provides expertise in Next Generation Sequencing (NGS) technologies to provide users with full spectrum of genomic services, including microarray analysis (ie genotyping and methylation arrays), NGS library preparation, short-read and long-read sequencing, genotyping.

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• RRID
• 1 month ago - submitted by Edyta Vieth

A free software for Mac OS X which designs long oligos for DNA microarrays, primers for PCR, siRNAs, and more��

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• SciCrunch
• 13 years ago - by Anonymous

Core specializes in oral microbial genomics, taxonomy, phylogenetics and the next generation sequence (NGS) data analysis with both in house and cloud high performance computational resource. In addition to supporting funded bioinformatics projects, Bioinformatics Core will also provide computational support to Forsyth and other researchers for processing, analyzing, and interpreting biological data.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Web-based and standalone application that facilitates multi-omics data visualization, exploration, integration, and analysis by providing easy access to dedicated and interactive protocols. It implements classical ordination techniques and the inference of omics-based (multilayer) networks to mine complex biological systems, and identify robust biomarkers linked to specific contextual parameters or biological states.

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• RRID
• 1 month ago - submitted by Florian Johann Gustav Waleczek

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• SciCrunch
• 15 years ago - submitted by Andrea Stagg

Software R package used to karyoplots. Bioconductor package to plot customizable genomes displaying arbitrary data.

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• RRID-Legacy
• 5 years ago - submitted by Santosh Kumar