We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Core specializes in metabolomic analysis. Provides Orbitrap Exploris 240 mass spectrometer, as well as dedicated staff for consultation and the analysis of biological samples.
Software for sequential partitioning, clustering and peak detection of centroided LC-MS mass spectrometry data (.mzXML). Interactive result and raw data plot.
Source code of a Cytoscape plugin for functional enrichment visualization. It organizes gene-sets, such as pathways and Gene Ontology terms, into a network to reveal which mutually overlapping gene-sets cluster together.
Web server for accurate local and global model quality estimates. Composite scoring function to derive entire structure and residue absolute quality estimates on basis of one single model.
Consortium serving to develop and qualify promising biomarkers in order to help accelerate the delivery of successful new technologies, medicines and therapies for prevention, early detection, diagnosis and treatment of disease. Current core disease areas of focus include Cancer, Inflammation and Immunity, Metabolic Disorders, and Neuroscience. One of the most difficult tasks facing biomarker assessment and evaluation is harmonizing the approaches of various stakeholders--government, industry, non-profits and foundations, providers, and academic institutions. Consortium founding members and other partners recognize the critical need for a coordinated cross-sector partnership effort. The Biomarkers Consortium brings together the expertise and resources of various partners to rapidly identify, develop, and qualify potential high-impact biomarkers. Biomarkers Consortium Goals: * Facilitate the development and qualification of biomarkers using new and existing technologies; * Help qualify biomarkers for specific applications in diagnosing disease, predicting therapeutic response or improving clinical practice; * Generate information useful to inform regulatory decision making; * Make consortium project results broadly available to the entire scientific community.
Alignment software for large-scale protein contact or protein-protein interaction prediction optimized for speed through shorter runtimes. FreeContact provides the opportunity to compute contact predictions in any environment (desktop or cloud).
Provides specialized resources and expertise to support scientists that want to incorporate systemic measures of mouse activity, metabolism and feeding. The systems are also embedded within light regulated environments to capture circadian, time of day, based outcomes.Supports scientists wanting to perform circadian type analyses with either pre-clinical or clinical time series data. Supports scientists wanting to incorporate -Omics measures into their studies with experience in genomics, proteomics and metabolomics assays/analyses. These services are available to support new investigators, early-stage investigators and current investigators in aging.
A free, open-source, computationally efficient Java program for comparative analyses of QTL mapping data and population simulation that runs on any computer operating system. (entry from Genetic Analysis Software) It is written with a plug-in architecture for ready extensibility. The software accommodates line-cross mating designs consisting of any arbitrary sequence of selfing, backcrossing, intercrossing and haploid-doubling steps that includes map, population, and trait simulators; and is scriptable. Source code is available on request.
Software for an integrated network combining multiple biological network database sources into a single human protein interactome. The software package contains gene interaction pairs corresponding to the unified global network.
Core Facility with conventional, full-spectrum, cell sorting and flow cytometry services. Training provided by core personnel.
Ontology for describing NMR experiments and acquisitions.
Software for a Python feature selection repository that contains a variety of feature selection algorithms, including traditional feature selection algorithms and some structural and streaming feature selection algorithms. It serves as a platform for facilitating feature selection application, research and comparative study.
Facility utilizes LabMA system developed by Luminex Co., for protein analysis that permits simultaneous quantitative analysis of up to 100 different proteins, peptides, or RNA molecules in single microtiter well. Commercially available assays from Millipore, R&D Systems, Bio-Rad or Thermofisher are also used for analysis.
Organization that provides biomedical researchers with online tools and a web portal enabling them to access, review, and integrate disparate ontological resources in all aspects of biomedical investigation and clinical practice. A major focus of the work involves the use of biomedical ontologies to aid in the management and analysis of data derived from complex experiments.
Software tool as robust preprocessing pipeline for functional MRI.Used for preprocessing of diverse fMRI data.
Core provides consultation regarding study design, statistical analyses, power and sample size calculations and data collection for clinical and translational studies and grant applications. BERD offers consultation for collecting and managing data using the REDCap system. BERD also offers a series of workshops to provide essential elements involved in data collection, data management and creating reports for research studies.
Community-driven organization that develops and disseminates software for geophysics and related fields. They host codes in a wide range of disciplines in geodynamics and computational science including geodynamo, long-term tectonics, magma migration, mantle dynamics, seismology, and short-term crustal dynamics.
Software for determination of cryo-EM structures. It employs an empirical Bayesian approach to refinement of (multiple) 3D reconstructions or 2D class averages in electron cryo-microscopy.
Core provides collection of obstetric biological materials from prenatal visits through delivery along with annotated clinical information. In addition to specimen access, MOMI staff can provide study design assistance as needed.
Software for meta-analysis of genome-wide SNP association results.