We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
A database-based neuron simulation tool. An innovative approach to large-scale, biologically plausible, neural-network simulation library. Based on data structures and methods directly coded into database, information flow implying separation of data representing neurons, conceived to share load on multiple machines and calibrating operational load on each machine.
Core provides sample preparation, metal extraction, dissolved solids measurement, analytic consultation, and technical writing assistance) in support of wide range of clinical and biomedical research projects.Instruments include Agilent 5100 SVDV Inductively-Coupled Plasma-Optical Emission Spectrometer, SPS3 Robotic Autosampler,MARS5 Microwave Sample Digestion Oven,ICPExpert Advanced Workstation.Analytic Capabilities:Simultaneous, multi-element quantitation over wide dynamic range;Broad elemental detection capability with high precision and sensitivity;Compatible with range of clinical, nutritional, basic research, and pharmaceutical samples;Tolerant of high total dissolved solids and complex matrix components;NIST-traceable calibrants, standards, and other QA/QC controls included in analyses.
Provides services and instrumentation including Illumina Next-Generation Sequencing, Single Cell Analysis and Spatial Transcriptomics. These techniques are developed and optimized by our lab scientists to deliver the highest-possible quality sequencing data from a wide variety of sample types such as peripheral blood, bone marrow, fresh frozen tissue and FFPE-derived tumor samples.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 28,2023. Platform for Neuroscientists to describe neurons and neural circuitry. Registered users may edit. The ultimate goal is advance the field of Neuromics by creating an encyclopedia of neurons and neural circuitry. NOTE: The database is no longer being maintained due to lack of funding.
Software tool to perform intersectional genetics-related operations to find VEnCodes using databases provided by FANTOM5 consortium, namely CAGE enhancer and transcription start site (TSS) databases.
Software R package contains functions for drawing survival curves using 'ggplot2'.
A single nucleotide variant caller optimised for identifying somatic variants in low cellularity cancer samples.
Software R package for computing and annotating genomic ranges. Used for storing and manipulating genomic intervals and variables defined along genome.
Core offers recombinant protein expression and purification in E. coli systems to investigators for functional and structural studies. Services include vector construction, expression optimization, protein purification using FPLC, and isotopically labeled protein expression for NMR. Clients can choose from expression strain delivery, optimized protocols, and/or purified protein, with fast turnaround times and consultation throughout the process.
THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone., documented on August 1, 2015. Consortium that aims to facilitate interdisciplinary collaborations to advance the understanding of pancreatic islet development and function, with the goal of developing innovative therapies to correct the loss of beta cell mass in diabetes, including cell reprogramming, regeneration and replacement. They are responsible for collaboratively generating the necessary reagents, mouse strains, antibodies, assays, protocols, technologies and validation assays that are beyond the scope of any single research effort. The scientific goals for the BCBC are to: * Use cues from pancreatic development to directly differentiate pancreatic beta cells and islets from stem / progenitor cells for use in cell-replacement therapies for diabetes, * Determine how to stimulate beta cell regeneration in the adult pancreas as a basis for improving beta cell mass in diabetic patients, * Determine how to reprogram progenitor / adult cells into pancreatic beta-cells both in-vitro and in-vivo as a mean for developing cell-replacement therapies for diabetes, and * Investigate the progression of human type-1 diabetes using patient-derived cells and tissues transplanted in humanized mouse models. Many of the BCBC investigator-initiated projects involve reagent-generating activities that will benefit the larger scientific community. The combination of programs and activities should accelerate the pace of major new discoveries and progress within the field of beta cell biology.
Web tool for display, annotation and management of phylogenetic trees. Accessible with any modern web browser.
Software interface for interacting with brain atlases. Python client to brain atlas framework that integrates brain parcellations and reference spaces at different spatial scales, and connects them with broad range of multimodal regional data features. It aims to facilitate programmatic and reproducible incorporation of brain parcellations and brain region features from different sources into neuroscience workflows.
A blog that explores local science, nature, and environment issues & experiences in Northern California. A collaborative effort, our many writers come from local museums, zoos, science centers and research institutions, as well as KQED''s TV and Radio producers covering stories in the field.
Data and information collection and repository for biological activities of small molecules and small interfering RNAs (siRNAs) hosted by the US National Institutes of Health (NIH). Used to select and summarize the bioactivities of tested substances.
Software pipeline for universal mapping of ATAC-seq.
The core mission of the AXA Research Fund is to finance basic research contributing to understand and prevent risks. We support innovative and cutting-edge projects within three areas: environmental, life, and socio-economic risks. Only research institutions may submit applications. * Funding for research projects, postdoc and graduate fellowships, and long and short term projects * Encourages international applicants and research around the world Research projects funded by the Fund must fall within the scope of one of the themes identified by the AXA Scientific Board. The themes for 2011 are identified below: * Life risks ** Aging & Long-term care ** Biomedical risks ** Addictions and risky behaviors * Socio-economic risks ** Geopolitical risks ** Macroeconomic and financial systemic risks ** Individual and collective behaviors when facing uncertainties ** Large corporate risks * Environmental risks ** Climate change ** Natural hazards ** Human driven environmental changes
Software tool to searches one or more input files for lines containing a match to a specified pattern. Prints lines that contain match for one or more patterns. Command-line utility for searching plain-text data sets for lines that match regular expression. When finds match, it copies line to standard output (by default), or produces whatever other sort of output you have requested with options.
Stand-alone Raspberry Pi-enabled IoT system to monitor near-realtime sensor data in MyVivarium web app. Used to track environmental conditions of vivaria.
The CEI Science & Technology Network (S&TN), launched at the beginning of 2004, is composed of sevenTrieste-based research centres and their partners in the CEI region. With the aim to strengthen scientific and technological cooperation, the S&TN provides financial support for the organization of seminars, conferences, workshops and training courses. Young scientists from CEI countries, especially non-EU member States, are offered the opportunity to attend such activities and carry out scientific research on various topics in one of the seven Lead Institutions (LIs). The area of cooperation of each Lead Institution is separately defined in a three-year Protocol complemented by an annual Work Programme. During 2004-2009, the Network''s Lead Institutions implemented a number of activities, some of which in partnership with other institutions from CEI countries. This cooperation started up the Secondary Network whose further enhancement will be the main challenge in the future years. The CEI Research Fellowship Programme The CEI Research Fellowship Programme was established in 2005 to enable mobility across the CEI region by giving selected scientists the possibility of carrying out research in one of the Network''s Lead Institutions. In the time-frame 2005 - 2009, the request for fellowships has constantly increased and witnessed the effectiveness of the Programme. Taking this into account, in 2008 the CEI-ES started to explore EU funding opportunities in order to develop its Research Fellowship Programme. A joint proposal named CERES (CEI Research Fellowship Programme) was submitted to the European Commission under the Seventh Framework Programme for Research and Technological Development (FP7). CERES was approved and is currently under implementation. EU Funding opportunities for the CEI Science & Technology Network Following the successful experience of CERES, the CEI-ES, along with the Network''s Lead Institutions, will continue to look into funding opportunities offered by the EU with the ultimate aim to support mobility of researchers across the CEI area and promote significant progress in the S&T sector.
Consortium to unite efforts and resources from experts across globe to advance effective, antibody based therapies against novel coronavirus, SARS-CoV-2. Represents multidisciplinary convergence of structural biology, virologists, immunologists, clinicians and bioinformaticians from academic and industry settings. Collects antibodies for testing as part of CoVICS. Contributed antibodies are blinded and will only be known as code name. Antibody contributors will be able to see performance of their own molecules and take part in analysis. Contributors retain ownership of their antibodies and may continue to publish on them using original antibody names. Goal is to determine relative in vitro potency and in vivo efficacy using centralized standardized assays to identify best individual mAbs and rational combinations of mAbs. Consortium will recommend ideal therapeutic molecules for human use to protect vulnerable populations from COVID-19 disease. CoVIC database (CoVIC-DB) will serve as clearinghouse for monoclonal antibodies against SARS-CoV-2. Database will catalog contributed antibodies in searchable resource and provide interactive analysis tools for comparisons among them.