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Immunology is a wikibook with the following contents: * Introduction * Organs of the Immune System * Cells of the Immune System * Antigens * Antibodies * Immune System Genetics * Antibody/Antigen Interactions * Major Histocompatibility Complex * Antigen Processing and Presentation * T Cells * B Cells * Cell-Mediated Immune Response * Cytokines * The Complement System * Inflammation * Hypersensitivity * Infectious Disease * Immunodeficiency * Autoimmunity * Transplants * Cancer * Vaccines * Experimental Methods in Immunology You may download as a PDF or print it.

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• SciCrunch
• 17 years ago - by Anonymous

National High Magnetic Field Laboratory (MagLab) site. It provides researchers with advanced NMR, MRI, and spectroscopy tools (human/animal imaging) for biomedical studies, specializing in high-field magnetic resonance technology. Hosts spectrometers and scanners, including high-field NMR (up to 1.5 GHz), MR microscopy, and human/animal MRI systems (e.g., 3T and 900 MHz). Offers expertise in high-resolution solution NMR, solid-state NMR, and specialized imaging for in vivo animal models and humans.Features an RF coil lab that designs, builds, and tests custom MRI/NMR coils to optimize data collection. Supports research into Alzheimer's, cancer, metabolism, and brain development.

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• SciCrunch
• 7 years ago - submitted by Leah Booher

Global provider of genetically modified rodent models and innovative cell and gene therapy solutions for research and development, including: disease model development, AAV discovery, drug efficacy studies, and more.

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• RRID
• 2 years ago - submitted by Mason Pairish

Founded in 1982 and headquartered in Virginia Beach, VA, LifeNet Health Inc., is a leading biomedical alloengineering organization and organ and tissue donation agency whose mission is saving lives and restoring health. LifeNet Health of Florida is a fully owned subsidiary dedicated to the recovery of tissue in Northern Florida, improving the awareness of tissue donation and educating the public about donation in the Northern Florida Community. Our mission is to improve upon the awareness of tissue donation within the community as well as to provide human tissue for transplant. We strive to give back to the community by providing an extensive public education program regarding donation, as well as being involved and making contributions that we feel will benefit the local community as a whole. Our efforts with total quality management have solidified our belief that LifeNet Health of Florida, Inc., must be driven by excellence in service and uncompromising quality. By the continuous improvement of processes and services leading to a better understanding of the entire donor process for both hospital personnel and members of our community.

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• SciCrunch
• 16 years ago - by Anonymous

Repository of sequenced antibodies, integrating curated information about antibody and its antigen with cross links to standardized databases of chemical and protein entities. Manually curated repository of sequenced antibodies, developed by Geneva Antibody Facility at University of Geneva, in collaboration with CALIPHO and Swiss Prot groups at SIB Swiss Institute of Bioinformatics. Database provides list of sequenced antibodies with their known targets. Each antibody is assigned unique ID number that can be used in academic publications to increase reproducibility of experiments.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

This is the description of your tool/resource, which will be shown on the Tool/Resource Summary page, in search results, etc. It should not be as comprehensive and as formal as the Tool/Resource Purpose and Summary description (step 3), so please feel free to use concise and catchy wording. Maximum length is 1023 characters. This description may be changed once the tool/resource has been registered.

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• NIF
• 2 years ago - by Anonymous

Database of the most recent sequence updates and annotations for the L. major genome. New annotations are constantly being added to keep up with published manuscripts and feedback from the Trypanosomatid research community. You may search by Protein Length, Molecular Mass, Gene Type, Date, Location, Protein Targeting, Transmembrane Helices, Product, GO, EC, Pfam ID, Curation and Comments, and Dbxrefs. BLAST and other tools are available. Leishmania species cause a spectrum of human diseases in tropical and subtropical regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase haploid genome of Leishmania major (Friedlin strain) and predict 911 RNA genes, 39 pseudogenes, and 8272 protein-coding genes, of which 36% can be ascribed a putative function. These include genes involved in host-pathogen interactions, such as proteolytic enzymes, and extensive machinery for synthesis of complex surface glycoconjugates. The Pathogen Genomics group at the Wellcome Trust Sanger Institute played a major role in sequencing the genome of Leishmania major (see Ivens et al.) Details of the centres involved and which chromosomes they sequenced, are given. The sequence data were obtained by adopting several parallel approaches, including complete cosmid sequencing, whole chromosome shotguns and/or BAC sequencing/skimming. The Leishmania parasite is an intracellular pathogen of the immune system targeting macrophages and dendritic cells. The disease Leishmaniasis affects the populations of 88 counties worldwide with symptoms ranging from disfiguring cutaneous and muco-cutaneous lesions that can cause widespread destruction of mucous membranes to visceral disease affecting the haemopoetic organs. In collaboration with GeneDB, the EuPathDB genomic sequence data and annotations are regularly deposited on TriTrypDB where they can be integrated with other datasets and queried using customized queries.

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• SciCrunch
• 16 years ago - by Anonymous

Software R package for estimating structural equation models using instrumental variables.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Software package for optimal matching in R. Distance based bipartite matching using minimum cost flow, oriented to matching of treatment and control groups in observational studies. Routines are provided to generate distances from generalised linear models (propensity score matching), formulas giving variables on which to limit matched distances, stratified or exact matching directives, or calipers, alone or in combination.

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• RRID
• 2 years ago - by Anonymous

The PSP Association is dedicated to the support of people with Progressive Supranuclear Palsy (PSP) and those who care for them. We also support those with the related, but rarer, disease Cortico Basal Degeneration (CBD). We fund research to better understand the possible causes of PSP and CBD, to find ways to achieve earlier and better diagnosis and to develop treatments that could potentially slow down, or even halt, the progression of these diseases. We support patients, families and carers through the services we offer on a UK-wide basis, through our Nurse Specialist helpline, our Local Support Groups, our publications (including the comprehensive Carers'' Information Pack) and our Annual Symposium for carers and therapists. We raise awareness of PSP and CBD on a local and national level and work in partnership with the relevant bodies and umbrella organisations in the UK to seek to make a positive difference to the lives of people with PSP and CBD. Registered charity numbers: England & Wales 1037087 / Scotland: SC041199.

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• SciCrunch
• 16 years ago - by Anonymous

Collection of color illustrations that follow main events of embryogenesis and post embryonic development of Drosophila.

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• RRID-Legacy
• 7 years ago - submitted by Ethan Badger

Community-driven cancer classification platform encompassing rare and common cancers that provides clinically relevant and appropriately granular cancer classification for clinical decision support systems and oncology research. Cancer classification system for precision oncology.

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• RRID
• 1 year ago - by Anonymous

The Human Reference Genetic Material Repository makes available DNA from a single individual, J. Craig Venter, whose genome has been sequenced and assembled. The DNA samples are prepared from a lymphoblastoid cell line established at Coriell Cell Repositories from a sample of peripheral blood. The DNA samples are available in 50 microgram aliquots. The lymphoblastoid cell line is not available for distribution. The human DNA sample provided is that of J. Craig Venter whose DNA from white blood cells and sperm was sequenced using Sanger chemistry (ABI Capillary Electrophoresis Platforms 3700 and 3730xl), assembled using the Celera Assembler and was published in PLoS Biology . J. Craig Venter, born on 14 October 1946, is a Caucasian male of self-reported European-American ancestry. The data available on this sample, whose genome assembly is referred to as HuRef, includes: * Whole Genome Shotgun Sequencing data * Sequence trace set deposited by JCVI in the NCBI trace archive * Human Genome Browser displaying sequence assembly, DNA variants and gene annotations Additional data sets from this study include: * Full set of Sanger reads used for genome assembly * SNP and insertion/deletion variant on the human genome sequence coordinates (NCBI version 36) * Affymetrix 500K GeneChip data * Illumina HumanHap650Y Genotyping BeadChip data Given the amount of data publicly available the genomic content of this sample, HuRef will be useful as a reference for many genetic studies.

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• SciCrunch
• 16 years ago - by Anonymous

Project focused on generating targeted knockout mutations in mouse ES cells. Second phase, KOMP2, relies upon successful generation of strains of knockout mice from these ES cells. Information from JAX about their contributions to KOMP project.

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• RRID-Legacy
• 7 years ago - submitted by Ethan Badger

Software repository is part of the open Metadata Initiative for Neuroscience Data Structures (openMINDS). It extends openMINDS, by providing metadata schemas for representing publications in neuroscience, including interactive publications such as Live Papers. It includes schemas for articles, books, preprints, blog posts, live papers, etc., linked to other openMINDS entities such as Datasets. The schemas closely follow those in Schema.org but extend them for improved interoperability with openMINDS.

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• RRID
• 1 year ago - submitted by Lyuba Zehl

Software that places query sequences on a fixed reference phylogenetic tree to maximize phylogenetic likelihood or posterior probability according to a reference alignment. Pplacer is designed to be fast, to give useful information about uncertainty, and to offer advanced visualization and downstream analysis.

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• SciCrunch
• 13 years ago - by Anonymous

Database for insights into single cell gene expression profiles during human developmental processes. Interactive database provides DE gene lists in each developmental pathway, t-SNE map, and GO and KEGG enrichment analysis based on these differential genes.

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• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Facility offers preparation and visualization ranging from standard 2D EM methods to high resolution 3D cryo-EM. Instruments, training and assisted use are available for Brandeis faculty, staff, and lab members, as well as members of the broader scientific community, including other academic institutions and for-profit organizations.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

California Transplant Services (CTS) is a full service eye and tissue bank headquartered in Carlsbad, California. CTS is a California non-profit public benefit corporation qualified by the IRS as a section 501(c)3 public charity, licensed by the California Department of Public Health as a Tissue Bank and registered and inspected by the United States Food and Drug Administration. We were also inspected by the American Association of Tissue Banks in September of 2003 and awarded Accreditation in December 2003. California Transplant Services is a Member of the Eye Bank Association of America. We are registered in California with the Office of Charitable Trusts. Most of CTS California Transplant''s fulltime staff are Certified Tissue Bank Specialists (CTBS) by the AATB or Certified Eye Bank Technicians (CEBT) by the Eye Bank Association of America. CTS staffing includes fulltime and part time tissue procurement specialists. CTS helps tissue banks by providing 24 hour tissue placement services from it''s west coast USA distribution center. CTS has provided cornea and bone tissue placement services nationwide since 1994.

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• SciCrunch
• 16 years ago - by Anonymous

Integrated genomic and functional genomic database for Entamoeba and Acanthamoeba parasites. Contains genomes of three Entamoeba species and microarray expression data for E. histolytica. Integrates whole genome sequence and annotation and includes experimental data and environmental isolate sequences provided by community researchers.

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• RRID-Legacy
• 7 years ago - by Anonymous