Sharf et al., Biol Psychiatry. 2008 | Fos FBJ osteosarcoma oncogene | | Ventral tegmental area | SB-334867 vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | | immunohistochemistry | Chronic morphine | table:1, Cell counts for immunohistochemical quantification are indicated., TH and c-Fos double-labeling in the VTA and LC, c-Fos single-labeling in the NAc |
Sharf et al., Biol Psychiatry. 2008 | Th Tyrosine hydroxylase | | Locus ceruleus | SB-334867 vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | | immunohistochemistry | Morphine withdrawal | table:1, Cell counts for immunohistochemical quantification are indicated., TH and c-Fos double-labeling in the VTA and LC, c-Fos single-labeling in the NAc |
Sharf et al., Biol Psychiatry. 2008 | Fos FBJ osteosarcoma oncogene | | Core of nucleus accumbens | SB-334867 vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | No change in staining | immunohistochemistry | Morphine withdrawal | table:1, Cell counts for immunohistochemical quantification are indicated., TH and c-Fos double-labeling in the VTA and LC, c-Fos single-labeling in the NAc |
Sharf et al., Biol Psychiatry. 2008 | Hcrt Hypocretin | | Lateral region of the lateral hypothalamus | Naloxone vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | | immunohistochemistry | Chronic morphine + SB-334867 | table:1, Cell counts for immunohistochemical quantification are indicated., Orexin and c-Fos double-labeling in the LH |
Sharf et al., Biol Psychiatry. 2008 | Fos FBJ osteosarcoma oncogene | | Lateral region of the lateral hypothalamus | SB-334867 vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | | immunohistochemistry | Morphine withdrawal | table:1, Cell counts for immunohistochemical quantification are indicated., Orexin and c-Fos double-labeling in the LH |
Sharf et al., Biol Psychiatry. 2008 | Th Tyrosine hydroxylase | | Locus ceruleus | SB-334867 vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | No change in staining | immunohistochemistry | Chronic morphine | table:1, Cell counts for immunohistochemical quantification are indicated., TH and c-Fos double-labeling in the VTA and LC, c-Fos single-labeling in the NAc |
Sharf et al., Biol Psychiatry. 2008 | Hcrt Hypocretin | | Lateral region of the lateral hypothalamus | SB-334867 vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | | immunohistochemistry | Morphine withdrawal | table:1, Cell counts for immunohistochemical quantification are indicated., Orexin and c-Fos double-labeling in the LH |
Sharf et al., Biol Psychiatry. 2008 | Th Tyrosine hydroxylase | | Lateral region of the lateral hypothalamus | SB-334867 vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | | immunohistochemistry | Chronic morphine | table:1, Cell counts for immunohistochemical quantification are indicated., Orexin and c-Fos double-labeling in the LH |
Sharf et al., Biol Psychiatry. 2008 | Th Tyrosine hydroxylase | | Ventral tegmental area | Naloxone vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | No change in staining | immunohistochemistry | Chronic morphine + SB-334867 | table:1, Cell counts for immunohistochemical quantification are indicated., TH and c-Fos double-labeling in the VTA and LC, c-Fos single-labeling in the NAc |
Sharf et al., Biol Psychiatry. 2008 | Th Tyrosine hydroxylase | | Ventral tegmental area | Naloxone vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | | immunohistochemistry | Chronic morphine + SB-334867 | table:1, Cell counts for immunohistochemical quantification are indicated., TH and c-Fos double-labeling in the VTA and LC, c-Fos single-labeling in the NAc |
Sharf et al., Biol Psychiatry. 2008 | Th Tyrosine hydroxylase | | Dorsomedial hypothamalus | Naloxone vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | Increased staining | immunohistochemistry | Chronic morphine | table:1, Cell counts for immunohistochemical quantification are indicated., Orexin and c-Fos double-labeling in the LH |
Sharf et al., Biol Psychiatry. 2008 | Th Tyrosine hydroxylase | | Dorsomedial hypothamalus | SB-334867 vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | | immunohistochemistry | Morphine withdrawal | table:1, Cell counts for immunohistochemical quantification are indicated., Orexin and c-Fos double-labeling in the LH |
Sharf et al., Biol Psychiatry. 2008 | Th Tyrosine hydroxylase | | Locus ceruleus | Naloxone vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | No change in staining | immunohistochemistry | Chronic morphine | table:1, Cell counts for immunohistochemical quantification are indicated., TH and c-Fos double-labeling in the VTA and LC, c-Fos single-labeling in the NAc |
Sharf et al., Biol Psychiatry. 2008 | Fos FBJ osteosarcoma oncogene | | Ventral tegmental area | SB-334867 vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | No change in staining | immunohistochemistry | Morphine withdrawal | table:1, Cell counts for immunohistochemical quantification are indicated., TH and c-Fos double-labeling in the VTA and LC, c-Fos single-labeling in the NAc |
Sharf et al., Biol Psychiatry. 2008 | Fos FBJ osteosarcoma oncogene | | Shell of nucleus accumbens | Naloxone vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | Increased staining | immunohistochemistry | Chronic morphine | table:1, Cell counts for immunohistochemical quantification are indicated., TH and c-Fos double-labeling in the VTA and LC, c-Fos single-labeling in the NAc |
Sharf et al., Biol Psychiatry. 2008 | Th Tyrosine hydroxylase | | Lateral region of the lateral hypothalamus | Naloxone vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | No change in staining | immunohistochemistry | Chronic morphine + SB-334867 | table:1, Cell counts for immunohistochemical quantification are indicated., Orexin and c-Fos double-labeling in the LH |
Sharf et al., Biol Psychiatry. 2008 | Th Tyrosine hydroxylase | | Dorsomedial hypothamalus | SB-334867 vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | | immunohistochemistry | Chronic morphine | table:1, Cell counts for immunohistochemical quantification are indicated., Orexin and c-Fos double-labeling in the LH |
Sharf et al., Biol Psychiatry. 2008 | Fos FBJ osteosarcoma oncogene | | Core of nucleus accumbens | Naloxone vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | Increased staining | immunohistochemistry | Chronic morphine | table:1, Cell counts for immunohistochemical quantification are indicated., TH and c-Fos double-labeling in the VTA and LC, c-Fos single-labeling in the NAc |
Sharf et al., Biol Psychiatry. 2008 | Fos FBJ osteosarcoma oncogene | | Ventral tegmental area | Naloxone vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | | immunohistochemistry | Chronic morphine + SB-334867 | table:1, Cell counts for immunohistochemical quantification are indicated., TH and c-Fos double-labeling in the VTA and LC, c-Fos single-labeling in the NAc |
Sharf et al., Biol Psychiatry. 2008 | Th Tyrosine hydroxylase | | Ventral tegmental area | SB-334867 vs. Saline | C57BL/6J Mouse: Male, 8-12 weeks prior to the onset of the experiments Adult mouse | No change in staining | immunohistochemistry | Morphine withdrawal | table:1, Cell counts for immunohistochemical quantification are indicated., TH and c-Fos double-labeling in the VTA and LC, c-Fos single-labeling in the NAc |