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The DRG provides differential gene expression data relevant to addiction where data types include the effects of a drug, strain, or knockout on a particular gene, in a particular brain region. Share your data set.
(last updated: Apr 8, 2017)
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Expression Gene Information Molecule| Resource | Gene Name | Probe ID | Brain Region | Exp vs Control | Organism | Expression | |||
|---|---|---|---|---|---|---|---|---|---|
| Yu et al., Physiol Genomics. 2005 | Brain creatine kinase (Ckb) | Striatum | Adenosine A2A receptor (A2AR) knock out vs. Wild type | Adenosine A2A receptor (A2AR) knock out Mouse: Male, roughly 6-8 weeks Adolescent - Adult mouse | Decreased expression | dna microarray | Vehicle | table:2, Comparative analysis of striatal gene expression regulated by A2AR KO and the A2AR antagonist SCH, A. A2AR KO-VEH vs. WT-VEH | |
| Zachariou et al., Biol.Psych 2008 | Fibroblast growth factor receptor 4 | 1427845_at | Locus ceruleus | Morphine pellet vs. Sham pellet | Adenylyl cyclase 8 Knockout Mouse: Male, 2-4 months Adult mouse | Increased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in AC8 KO |
| Zachariou et al., Biol.Psych 2008 | RIKEN cdna A730032A03 gene | 1457832_at | Locus ceruleus | Morphine pellet vs. Sham pellet | Adenylyl cyclase 8 Knockout Mouse: Male, 2-4 months Adult mouse | Decreased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in AC8 KO |
| Zachariou et al., Biol.Psych 2008 | Progestin and adipoq receptor family member viii | 1435246_at | Locus ceruleus | Morphine pellet vs. Sham pellet | Adenylyl cyclase 1 Knockout Mouse: Male, 2-4 months Adult mouse | Increased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in AC1 KO |
| Zachariou et al., Biol.Psych 2008 | Transglutaminase 2, c polypeptide | 1437277_x_at | Locus ceruleus | Morphine pellet vs. Sham pellet | Adenylyl cyclase 1 Knockout Mouse: Male, 2-4 months Adult mouse | Increased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in AC1 KO |
| Zachariou et al., Biol.Psych 2008 | Vacuolar protein sorting 13A (yeast) | 1459518_at | Locus ceruleus | Adenylyl cyclase 1 Knockout vs. Wildtype | Adenylyl cyclase 1 Knockout Mouse: Male, 2-4 months Adult mouse | Increased expression | dna microarray | None | table:S2, Baseline regulation of gene expression in the LC, Genes Significantly Regulated by AC1 KO vs WT |
| Zachariou et al., Biol.Psych 2008 | Expressed sequence c80292 | 1448056_at | Locus ceruleus | Morphine pellet vs. Sham pellet | Adenylyl cyclase 1 Knockout Mouse: Male, 2-4 months Adult mouse | Decreased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in AC1 KO |
| Zachariou et al., Biol.Psych 2008 | Transcribed locus | 1445314_at | Locus ceruleus | Morphine pellet vs. Sham pellet | C57BL/6 (Wildtype control) Mouse: Male, 2-4 months Adult mouse | Decreased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in WT |
| Zachariou et al., Biol.Psych 2008 | Nucleolar and spindle associated protein 1 | 1442830_at | Locus ceruleus | Morphine pellet vs. Sham pellet | Adenylyl cyclase 1 Knockout Mouse: Male, 2-4 months Adult mouse | Increased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in AC1 KO |
| Zachariou et al., Biol.Psych 2008 | NACHT, leucine rich repeat and PYD containing 4A | 1438077_at | Locus ceruleus | Adenylyl cyclase 1 Knockout vs. Wildtype | Adenylyl cyclase 1 Knockout Mouse: Male, 2-4 months Adult mouse | Increased expression | dna microarray | None | table:S2, Baseline regulation of gene expression in the LC, Genes Significantly Regulated by AC1 KO vs WT |
| Zachariou et al., Biol.Psych 2008 | Solute carrier family 39 (metal ion transporter), member 8 | 1416832_at | Locus ceruleus | Morphine pellet vs. Sham pellet | Adenylyl cyclase 8 Knockout Mouse: Male, 2-4 months Adult mouse | Decreased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in AC8 KO |
| Zachariou et al., Biol.Psych 2008 | Coiled-coil domain containing 99 | 1424971_at | Locus ceruleus | Morphine pellet vs. Sham pellet | C57BL/6 (Wildtype control) Mouse: Male, 2-4 months Adult mouse | Decreased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in WT |
| Zachariou et al., Biol.Psych 2008 | Fibromodulin | 1437685_x_at | Locus ceruleus | Morphine pellet vs. Sham pellet | Adenylyl cyclase 8 Knockout Mouse: Male, 2-4 months Adult mouse | Decreased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in AC8 KO |
| Zachariou et al., Biol.Psych 2008 | Mu27g11.x1 Soares_thymus_2nbmt Mus musculus cdna clone IMAGE:640676 3', mrna sequence. | 1453827_at | Locus ceruleus | Morphine pellet vs. Sham pellet | Adenylyl cyclase 8 Knockout Mouse: Male, 2-4 months Adult mouse | Decreased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in AC8 KO |
| Zachariou et al., Biol.Psych 2008 | L0022A02-3 NIA Mouse E12.5 Female Mesonephros and Gonads | 1458517_at | Locus ceruleus | Adenylyl cyclase 1 Knockout vs. Wildtype | Adenylyl cyclase 1 Knockout Mouse: Male, 2-4 months Adult mouse | Increased expression | dna microarray | None | table:S2, Baseline regulation of gene expression in the LC, Genes Significantly Regulated by AC1 KO vs WT |
| Zachariou et al., Biol.Psych 2008 | Olfactory receptor 78 | 1421507_at | Locus ceruleus | Morphine pellet vs. Sham pellet | C57BL/6 (Wildtype control) Mouse: Male, 2-4 months Adult mouse | Increased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in WT |
| Zachariou et al., Biol.Psych 2008 | BB560574 RIKEN full-length enriched | 1437502_x_at | Locus ceruleus | Morphine pellet vs. Sham pellet | Adenylyl cyclase 8 Knockout Mouse: Male, 2-4 months Adult mouse | Increased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in AC8 KO |
| Zachariou et al., Biol.Psych 2008 | Transcribed locus | 1444517_at | Locus ceruleus | Adenylyl cyclase 1 Knockout vs. Wildtype | Adenylyl cyclase 1 Knockout Mouse: Male, 2-4 months Adult mouse | Increased expression | dna microarray | None | table:S2, Baseline regulation of gene expression in the LC, Genes Significantly Regulated by AC1 KO vs WT |
| Zachariou et al., Biol.Psych 2008 | Serine (or cysteine) peptidase inhibitor, clade B, member 1a | 1416318_at | Locus ceruleus | Morphine pellet vs. Sham pellet | Adenylyl cyclase 8 Knockout Mouse: Male, 2-4 months Adult mouse | Decreased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in AC8 KO |
| Zachariou et al., Biol.Psych 2008 | Riken cdna 1110017i16 gene | 1428994_s_at | Locus ceruleus | Morphine pellet vs. Sham pellet | Adenylyl cyclase 1 Knockout Mouse: Male, 2-4 months Adult mouse | Increased expression | dna microarray | Chronic morphine | table:S1, Morphine regulation of gene expression in the LC in WT, AC1 KO, and AC8 KO, Genes Significantly Regulated by Morphine in AC1 KO |
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