Searching across hundreds of databases
Modern genetic approaches are powerful in providing access to diverse cell types in the brain and facilitating the study of their function. Here, we report a large set of driver and reporter transgenic mouse lines, including 23 new driver lines targeting a variety of cortical and subcortical cell populations and 26 new reporter lines expressing an array of molecular tools. In particular, we describe the TIGRE2.0 transgenic platform and introduce Cre-dependent reporter lines that enable optical physiology, optogenetics, and sparse labeling of genetically defined cell populations. TIGRE2.0 reporters broke the barrier in transgene expression level of single-copy targeted-insertion transgenesis in a wide range of neuronal types, along with additional advantage of a simplified breeding strategy compared to our first-generation TIGRE lines. These novel transgenic lines greatly expand the repertoire of high-precision genetic tools available to effectively identify, monitor, and manipulate distinct cell types in the mouse brain.
Pubmed ID: 30007418 RIS Download
Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.
Software performing alignment of high-throughput RNA-seq data. Aligns RNA-seq reads to reference genome using uncompressed suffix arrays.
View all literature mentionsThis polyclonal targets IgY (IgG) (H+L)
View all literature mentionsThis polyclonal targets IgG (H+L)
View all literature mentionsThis unknown targets Mouse IgG (H+L)
View all literature mentionsThis polyclonal targets GFP
View all literature mentionsThis monoclonal targets Choline Acetyltransferase
View all literature mentionsThis polyclonal targets Rabbit Tryptophan hydroxylase 2
View all literature mentionsThis monoclonal targets Serotonin Transporter clone 17-7A4
View all literature mentionsThis polyclonal targets Tyrosine Hydroxylase antibody - Neuronal Marker
View all literature mentionsThis unknown targets The immunogen used was recombinant 2A from foot and mouth virus1. The epitope is believed to be within the
View all literature mentionsThis monoclonal targets parvalbumin
View all literature mentionsSoftware performing alignment of high-throughput RNA-seq data. Aligns RNA-seq reads to reference genome using uncompressed suffix arrays.
View all literature mentionsSoftware used for visualizing and graphing data, image processing, and programming. It is designed for use by scientists and engineers and supports large data sets, evenly spaced data, and various data import formats. The software includes a suite of image processing operations for image filtering, manipulation, and quantification and is completely programmable.
View all literature mentionsProgramming language for all operating systems that lets users work more quickly and integrate their systems more effectively. Often compared to Tcl, Perl, Ruby, Scheme or Java. Some of its key distinguishing features include very clear and readable syntax, strong introspection capabilities, intuitive object orientation, natural expression of procedural code, full modularity, exception-based error handling, high level dynamic data types, extensive standard libraries and third party modules for virtually every task, extensions and modules easily written in C, C (or Java for Python, or .NET languages for IronPython), and embeddable within applications as a scripting interface.
View all literature mentionsMulti paradigm numerical computing environment and fourth generation programming language developed by MathWorks. Allows matrix manipulations, plotting of functions and data, implementation of algorithms, creation of user interfaces, and interfacing with programs written in other languages, including C, C++, Java, Fortran and Python. Used to explore and visualize ideas and collaborate across disciplines including signal and image processing, communications, control systems, and computational finance.
View all literature mentionsSoftware package as distribution of ImageJ and ImageJ2 together with Java, Java3D and plugins organized into coherent menu structure. Used to assist research in life sciences.
View all literature mentionsStatistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.
View all literature mentionsOpen source Java based image processing software program designed for scientific multidimensional images. ImageJ has been transformed to ImageJ2 application to improve data engine to be sufficient to analyze modern datasets.
View all literature mentionsMus musculus with name B6.Cg-Chrm2tm1.1Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Igs7tm170.1(tetO-GFP*/TPTE2*.CAG-tTA2)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Igs7tm169.1(tetO-GFP*/TPTE2*.CAG-tTA2)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Igs7tm162.1(tetO-GCaMP6s.CAG-tTA2)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Igs7tm161.1(tetO-EGFP.CAG-tTA2)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Igs7tm148.1(tetO-GCaMP6f.CAG-tTA2)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Igs7tm140.1(tetO-EGFP.CAG-tTA2)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Igs7tm139.1(tetO-EGFP.CAG-tdTomato.-tTA2)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Igs7tm136.1(tetO-COP3*/COP4*/EYFP)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Igs7tm134.1(tetO-COP4*H134R/EYFP)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Igs7tm133.1(tetO-apx1*)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Igs7tm90.1(tetO-COP4*/EGFP)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Gt(ROSA)26Sortm80.1(CAG-COP4*L132C/EYFP)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Gt(ROSA)26Sortm75.1(CAG-tdTomato*)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Gt(ROSA)26Sortm40.1(CAG-aop3/EGFP)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6;129S-Gt(ROSA)26Sortm34.1(CAG-Syp/tdTomato)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Vipr2em1.1(cre)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Slc32a1tm1.1(flpo)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6;129S-Slc17a8tm1.1(cre)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6;129S-Slc17a6tm1.1(flpo)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Rorbtm3.1(flpo)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Rasgrf2tm2.1(folA/flpo)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6;129S-Penktm2(cre)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6;129S-Pdyntm1.1(cre/ERT2)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Oxtrtm1.1(cre)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Npytm1.1(flpo)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Npr3tm1.1(cre)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6;129S-Htr1atm1.1(cre)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Gnb4tm1.1(cre/ERT2)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Fezf1tm1.1(cre/folA)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6;129S-Esr2tm1.1(cre)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6;129S-Cartpttm1.1(cre)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Calb1tm1.1(folA/cre)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6;129S-Calb1tm2.1(cre)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6;129S-Gt(ROSA)26Sortm65.1(CAG-tdTomato)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.129S4-Gt(ROSA)26Sortm3(phiC31*)Sor/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/J from IMSR.
View all literature mentionsThe SciCrunch Infrastructure was developed as a cooperative data platform to be used by diverse communities in making data more FAIR.
scicrunch.org
