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Saussurea costus alleviates ulcerative colitis by regulating the gut microbiota and improving intestinal barrier integrity.

Wen-Lin Pang | Tian-Gang Li | Yin-Ying Wang | Li-Yun Song | Li Li | Xiao-Ya Li | Yong Qiu | Zhong-Shan Yang
Frontiers in cellular and infection microbiology | 2025

The global health challenge of ulcerative colitis (UC) has been classified by the WHO as a modern refractory disease, commonly referred to as green cancer, with limited treatment options still available, highlighting the urgent need for the development of new therapeutic strategies. Recent pharmacological research has shown that traditional Chinese medicine saussurea costus (SC) possesses beneficial antibacterial and anti-inflammatory properties. Nevertheless, its underlying mechanism remains elusive.

Pubmed ID: 39936162

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