URL: https://www.jax.org/strain/000664
Proper Citation: RRID:IMSR_JAX:000664
Description: Mus musculus with name C57BL/6J from IMSR.
Species: Mus musculus
Synonyms: B6. B6J. Black 6. C57 Black. C57BL/6JAnu
Notes: gene symbol note: arylalkylamine N-acetyltransferase|NLR family; pyrin domain containing 12|CD5 antigen|nicotinamide nucleotide transhydrogenase|purinergic receptor P2X; ligand-gated ion channel; 7|cytochrome c oxidase subunit 7A2 like|annexin A6|cadherin related 23 (otocadherin)|forebrain weight 2|microwave induced increase in complement receptor B cells|glucose homeostasis QTL 3|latent transforming growth factor beta binding protein 4|glucose homeostasis QTL 1|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|nuclear encoded tRNA arginine 5 (anticodon TCT)|gamma-aminobutyric acid type A receptor subunit alpha 2|MX dynamin-like GTPase 1|forebrain weight 1|aryl-hydrocarbon receptor|beta-2 microglobulin|hemoglobin beta chain complex|glucose homeostasis QTL 2; inbred strain: Aanat|Nlrp12|Cd5|Nnt|P2rx7|Cox7a2l|Anxa6|Cdh23|Fbrwt2|Micrl|Gluchos3|Ltbp4|Gluchos1|Apobec3|n-TRtct5|Gabra2|Mx1|Fbrwt1|Ahr|B2m|Hbb|Gluchos2
Affected Gene: arylalkylamine N-acetyltransferase|NLR family; pyrin domain containing 12|CD5 antigen|nicotinamide nucleotide transhydrogenase|purinergic receptor P2X; ligand-gated ion channel; 7|cytochrome c oxidase subunit 7A2 like|annexin A6|cadherin related 23 (otocadherin)|forebrain weight 2|microwave induced increase in complement receptor B cells|glucose homeostasis QTL 3|latent transforming growth factor beta binding protein 4|glucose homeostasis QTL 1|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|nuclear encoded tRNA arginine 5 (anticodon TCT)|gamma-aminobutyric acid type A receptor subunit alpha 2|MX dynamin-like GTPase 1|forebrain weight 1|aryl-hydrocarbon receptor|beta-2 microglobulin|hemoglobin beta chain complex|glucose homeostasis QTL 2
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Issue
Warning this mouse may be epileptogenic. The cause seems to be that the GABAA receptor is expressed at very low levels compared to other mouse strains including the C57BL/6N, according to Hawkins (2016) and Mulligan (2019).
Source: Integrated Animals
Source Database: JAX Mice and Services