ApiNATOMY

ApiNATOMY

ApiNATOMY is a collection of methodologies that produces simple anatomy schematics and provides for the overlay of anatomy-related information onto the same diagram. It is used to build routing and connectivity graphs for anatomical entities. Such graphs support queries that, for instance, identify neural connections that course through a tract, nerve, or ganglion. ApiNATOMY-based knowledge, therefore, allows the SPARC user to determine the nuclei/grey matter regions affected by the transection of a nerve or the stimulation of a ganglion. The same routing information leveraged by the flat map graphical user interface (GUI; http://open-physiology-viewer.surge.sh/) may be used to discover metadata, SPARC experimental data, or simulation models that are located along the route of a tract, nerve, or ganglion. The development of multiscale route knowledge graphs is leveraging the ApiNATOMY knowledge representation.

A graphical depiction of an ApiNATOMY model relevant to defensive breathing and Superior Cervical Ganglion physiology is shown below.