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Hydrogen attenuates postoperative pain through Trx1/ASK1/MMP9 signaling pathway.

Juan Li | Shirong Ruan | Jinhui Jia | Qian Li | Rumeng Jia | Li Wan | Xing Yang | Peng Teng | Qilin Peng | Ya-Dan Shi | Pan Yu | Yinbing Pan | Man-Lin Duan | Wen-Tao Liu | Li Zhang | Liang Hu
Journal of neuroinflammation | 2023

Postoperative pain is a serious clinical problem with a poorly understood mechanism, and lacks effective treatment. Hydrogen (H2) can reduce neuroinflammation; therefore, we hypothesize that H2 may alleviate postoperative pain, and aimed to investigate the underlying mechanism.

Pubmed ID: 36737785

Research resources used in this publication

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Antibodies used in this publication

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Associated grants

  • Agency: General Projects of Traditional Chinese Medicine Administration of Jiangsu Province,
    Id: YB201821
  • Agency: Jiangsu Province Hospital (the First Affiliated Hospital with Nanjing Medical University) Clinical Capacity Enhancement Project,
    Id: JSPH-511B-2018-8
  • Agency: the National Natural Science Foundation of China,
    Id: 81971047
  • Agency: the National Natural Science Foundation of China,
    Id: 82204542
  • Agency: The Key Research and Development Plan of Jiangsu province,
    Id: BE2019732
  • Agency: Nanjing special fund for health science and technology development,
    Id: YKK19170
  • Agency: Natural Science Research Project of Universities in Jiangsu Province,
    Id: 21KJB310019

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This is a list of tools and resources that we have found mentioned in this publication.


C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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BV-2 (tool)

RRID:CVCL_0182

Cell line BV-2 is a Transformed cell line with a species of origin Mus musculus (Mouse)

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