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Regulation of Fatty Acid Oxidation by Twist 1 in the Metabolic Adaptation of T Helper Lymphocytes to Chronic Inflammation.

Kristyna Hradilkova | Patrick Maschmeyer | Kerstin Westendorf | Heidi Schliemann | Olena Husak | Anne Sae Lim von Stuckrad | Tilmann Kallinich | Kirsten Minden | Pawel Durek | Joachim R Grün | Hyun-Dong Chang | Andreas Radbruch
Arthritis & rheumatology (Hoboken, N.J.) | 2019

Inflamed tissue is characterized by low availability of oxygen and nutrients. Yet CD4+ T helper lymphocytes persist over time in such tissue and probably contribute to the chronicity of inflammation. This study was undertaken to analyze the metabolic adaptation of these cells to the inflamed environment.

Pubmed ID: 31131995

Research resources used in this publication

None found

Antibodies used in this publication

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Associated grants

  • Agency: Deutsche Forschungsgemeinschaft, International
    Id: SFB650
  • Agency: Leibniz-Gemeinschaft, International
  • Agency: Horizon 2020 Framework Programme, International
    Id: 777357
  • Agency: FP7 Ideas: European Research Council, International
    Id: 268987
  • Agency: Rheumastiftung, International
  • Agency: BSRT graduate school, International
  • Agency: EUTRAIN, International
  • Agency: European Union, International
    Id: FP7-PEOPLE-2011-ITN-289903

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