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Short-term consumption of a high-fat diet increases host susceptibility to Listeria monocytogenes infection.

Vanessa Las Heras | Adam G Clooney | Feargal J Ryan | Raul Cabrera-Rubio | Pat G Casey | Cara M Hueston | Jorge Pinheiro | Justine K Rudkin | Silvia Melgar | Paul D Cotter | Colin Hill | Cormac G M Gahan
Microbiome | 2019

A westernized diet comprising a high caloric intake from animal fats is known to influence the development of pathological inflammatory conditions. However, there has been relatively little focus upon the implications of such diets for the progression of infectious disease. Here, we investigated the influence of a high-fat (HF) diet upon parameters that influence Listeria monocytogenes infection in mice.

Pubmed ID: 30658700

Research resources used in this publication

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Associated grants

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PRISM (tool)

RRID:SCR_005375

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5,2022.Tool that predicts interactions between transcription factors and their regulated genes from binding motifs. Understanding vertebrate development requires unraveling the cis-regulatory architecture of gene regulation. PRISM provides accurate genome-wide computational predictions of transcription factor binding sites for the human and mouse genomes, and integrates the predictions with GREAT to provide functional biological context. Together, accurate computational binding site prediction and GREAT produce for each transcription factor: 1. putative binding sites, 2. putative target genes, 3. putative biological roles of the transcription factor, and 4. putative cis-regulatory elements through which the factor regulates each target in each functional role.

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RRID:SCR_014583

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RRID:SCR_015687

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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