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Publication

Protein imbalance in the development of skeletal muscle wasting in tumour-bearing mice.

Jacob L Brown | David E Lee | Megan E Rosa-Caldwell | Lemuel A Brown | Richard A Perry | Wesley S Haynie | Kendra Huseman | Kavithalakshmi Sataranatarajan | Holly Van Remmen | Tyrone A Washington | Michael P Wiggs | Nicholas P Greene
Journal of cachexia, sarcopenia and muscle | 2018

Cancer cachexia occurs in approximately 80% of cancer patients and is a key contributor to cancer-related death. The mechanisms controlling development of tumour-induced muscle wasting are not fully elucidated. Specifically, the progression and development of cancer cachexia are underexplored. Therefore, we examined skeletal muscle protein turnover throughout the development of cancer cachexia in tumour-bearing mice.

Pubmed ID: 30328290

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Associated grants

  • Agency: BLRD VA, United States
    Id: I01 BX002595
  • Agency: NIAMS NIH HHS, United States
    Id: R15 AR069913
  • Agency: NIA NIH HHS, United States
    Id: T32 AG052363
  • Agency: NIH HHS, United States
    Id: R15AR069913

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Statistical Analysis System (tool)

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Software platform to explore, analyze and visualize data. SAS 9.4 is part of SAS Platform. Standardized data governance and management from statistical software company SAS.

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The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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