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Long-term administration of olanzapine induces adiposity and increases hepatic fatty acid desaturation protein in female C57BL/6J mice.

Po-Hsun Hou | Geng-Ruei Chang | Chin-Pin Chen | Yen-Ling Lin | I-Shuan Chao | Ting-Ting Shen | Frank Chiahung Mao
Iranian journal of basic medical sciences | 2018

Weight gain and metabolic disturbances such as dyslipidemia, are frequent side effects of second-generation antipsychotics, including olanzapine. This study examined the metabolic effects of chronic olanzapine exposure. In addition, we investigated the hepatic fatty acid effects of olanzapine in female C57BL/6J mice fed a normal diet.

Pubmed ID: 29922430

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Scion Image (tool)

RRID:SCR_008673

THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. Commercial software vendor.

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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