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Deficiency of FAM3D (Family With Sequence Similarity 3, Member D), A Novel Chemokine, Attenuates Neutrophil Recruitment and Ameliorates Abdominal Aortic Aneurysm Development.

Li He | Yi Fu | Jingna Deng | Yicong Shen | Yingbao Wang | Fang Yu | Nan Xie | Zhongjiang Chen | Tianpei Hong | Xinjian Peng | Qingqing Li | Jing Zhou | Jingyan Han | Ying Wang | Jianzhong Xi | Wei Kong
Arteriosclerosis, thrombosis, and vascular biology | 2018

Chemokine-mediated neutrophil recruitment contributes to the pathogenesis of abdominal aortic aneurysm (AAA) and may serve as a promising therapeutic target. FAM3D (family with sequence similarity 3, member D) is a recently identified novel chemokine. Here, we aimed to explore the role of FAM3D in neutrophil recruitment and AAA development.

Pubmed ID: 29853563

Associated grants

None

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