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Integrated Clinical Trials is a virtual database currently indexing clinical trials from: EU Clinical Trials Register and ClinicalTrials.gov.
(last updated: Nov 28, 2022)
Clinical Trials Information| Database | Title | Recruitment | Conditions | Intervention | Sponsored By | Gender | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Clinicaltrials.gov | Intermittent Fasting Versus Daily Caloric Restriction for Weight Loss | Active, not recruiting | Obesity | Behavioral, Behavioral - Daily Caloric Restriction (DCR), Intermittent Fasting (IMF) | University of Colorado, Denver, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Other, NIH | 18 Years - 60 Years | N/A | Interventional | The primary aim of this study is to is to determine if intermittent fasting (IMF) is an effective dietary strategy for treatment of obesity. A 1 year randomized trial will be used to compare weight loss generated by IMF versus Daily Caloric Restriction (DCR). The targeted weekly energy deficit is designed to be similar (~30%) and a comprehensive behavioral support program will be provided to both groups. The primary outcome is weight change at the end of the 1 year intervention; follow up measures will also be obtained 6 months after completing the intervention. This study will provide robust data regarding weight loss effectiveness of IMF and will further our understanding of the impact of IMF on energy balance. | ||
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Clinicaltrials.gov | Motivation for Exercise and Physical Activity Adherence | Completed | Obesity | Behavioral - MOVE | University of Colorado, Denver, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Other, NIH | 18 Years - 60 Years | Observational | The limited success of our current approaches to increase adoption and maintenance of physical activity in adults with overweight and obesity is a substantial barrier to effectively address the current obesity epidemic. This mentored F32 application addresses the significant public health issue of obesity and associated risk of major chronic diseases by using mixed methods research to optimize an innovative, theoretically based physical activity intervention designed to enhance motivation for exercise in adults with overweight and obesity. | |||
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Clinicaltrials.gov | Linking Temporal Patterns of Modifiable Behaviors to Weight Loss Outcomes | Enrolling by invitation | Obesity, Weight Change, Body | University of Colorado, Denver, National Heart, Lung, and Blood Institute (NHLBI), Other, NIH | 18 Years - 60 Years | Observational [Patient Registry] | This study is designed as an observational trial. The objective of this study is to follow-up with participants 3 years after completion of an 18-month comprehensive behavioral weight loss intervention. Outcomes of interest include change in body weight, body composition, physical activity, energy intake, and sleep. In addition, investigators will explore the associations between current physical activity, sleep, and energy intake patterns and body weight regulation. | ||||
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Clinicaltrials.gov | Mediators of Abnormal Reproductive Function in Obesity (MARO) | Completed | Infertility, Female, Obesity | Other, Dietary Supplement, Drug, Drug - Microdialysis, Vascepa - Fish Oil, Aspirin, Pioglitazone | University of Colorado, Denver, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Other, NIH | Female | 18 Years - 60 Years | Early Phase 1 | Interventional | The study is seeking to understand how being overweight and obese makes women less fertile. The studies the investigators have done so far indicate that there is a hormone or other substance produced by fat that goes into the blood and reduces reproductive hormones in women who are overweight and obese. The present study will try to find the most promising substances by studying small numbers of women and trying to remove the substances that are causing the problem. Hypothesis: A circulating factor or factors, either hormonal, inflammatory or metabolic, causes relative pituitary hypofunction and correction of this reproductive deficit will allow obese women with infertility who have failed to reduce their body weight to normal to conceive, and may also prevent the horizontal passage of an adverse metabolic phenotype to the offspring. |
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