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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Contract research organization (CRO) that specializes in advanced tissue technologies. It offers services in histology, immunohistochemistry, digital pathology, and image analysis.
Proper citation: Reveal Biosciences (RRID:SCR_001021) Copy
http://www.scienceexchange.com/facilities/persmed
Life science consultancy and analysis service company. Analysis services include microarray analysis, next generation sequencing, experiment design, and biostatistics. Consultancy centers around experimental design in approaches involving large sets of patient-derived data.
Proper citation: PersMed (RRID:SCR_001025) Copy
Company which provides a suite of molecular biology and genomic services, including DNA sequencing by Sanger and Next Generation Sequencing. All services are offered at a research, GLP or clinical grade levels.
Proper citation: ACGT Inc. (RRID:SCR_001026) Copy
http://www.cbs.dtu.dk/services/gwBrowser/
An interactive web application for visualizing genomic data of sequenced prokaryotic chromosomes. It allows users to carry out various analyses such as mapping alignments of homologous genes to other genomes, mapping of short sequencing reads to a reference chromosome, and calculating DNA properties such as curvature or stacking energy along the chromosome. The GeneWiz browser produces an interactive graphic that enables zooming from a global scale down to single nucleotides, without changing the size of the plot. Its ability to disproportionally zoom provides optimal readability and increased functionality compared to other browsers. The tool allows the user to select the display of various genomic features, color setting and data ranges. Custom numerical data can be added to the plot allowing, for example, visualization of gene expression and regulation data. Further, standard atlases are pre-generated for all prokaryotic genomes available in GenBank, providing a fast overview of all available genomes, including recently deposited genome sequences.
Proper citation: GeneWiz browser (RRID:SCR_001454) Copy
http://viewer.shigen.info/cgi-bin/crispr/crispr.cgi
Web tool to show micro homology sequences striding over double strand break point created by CRISPR/Cas9 system. Used to search for CRISPR target site with micro-homology sequences. Used to predict deletion pattern.
Proper citation: NBRP Medaka CRISPR target site (RRID:SCR_018159) Copy
https://www.estimationstats.com/#/
Web application for data analysis and visualizing effect sizes. Data analysis with estimation graphics.
Proper citation: Estimation Stats (RRID:SCR_018321) Copy
http://www.detaibio.com/sms2/protein_gravy.html
Web protein hydrophilicity analysis tool.
Proper citation: protein hydrophilicity analysis tool (RRID:SCR_023015) Copy
http://www.salk.edu/science/core-facilities/behavior-testing-core/
Core facility that provides the resources to investigate sensory, motor and complex behavioral testing in rat and mouse models. The facility offers standard neurobehavioral tests, customized test batteries, training for independent use of the equipment, data interpretation and anlaysis.
Proper citation: Salk Institute Behavior Testing Core Facility (RRID:SCR_014840) Copy
Core provides consultation, training, software and educational tools in bioinformatics and graphics.
Proper citation: Whitehead Institute Bioinformatics and Research Computing Core Facility (RRID:SCR_017150) Copy
http://www.arrayserver.com/wiki/index.php?title=ArrayStudio_Online_Help
Software package which provides statistics and visualization for analysis of high dimensional quantification data including microarray or RTPCR data or Taqman data, genotype data including SNP or Copy Number data and Next Generation Sequencing data. Provides integrated environment for analyzing and visualizing high dimensional data.
Proper citation: Array Studio (RRID:SCR_010970) Copy
Database for microarray data storage, retrieval, analysis, and visualization.
Proper citation: UNC Microarray Database (RRID:SCR_010979) Copy
http://www.cbil.upenn.edu/cgi-bin/tess/tess
TESS is a web tool for predicting transcription factor binding sites in DNA sequences. It can identify binding sites using site or consensus strings and positional weight matrices from the TRANSFAC, JASPAR, IMD, and our CBIL-GibbsMat database. You can use TESS to search a few of your own sequences or for user-defined CRMs genome-wide near genes throughout genomes of interest. Search for CRMs Genome-wide: TESS now has the ability to search whole genomes for user defined CRMs. Try a search in the AnGEL CRM Searches section of the navigation bar.. You can search for combinations of consensus site sequences and/or PWMs from TRANSFAC or JASPAR. Search DNA for Binding Sites: TESS also lets you search through your own sequence for TFBS. You can include your own site or consensus strings and/or weight matrices in the search. Use the Combined Search under ''Site Searches'' in the menu or use the box for a quick search. TESS assigns a TESS job number to all sequence search jobs. The job results are stored on our server for a period of time specified in the search submit form. During this time you may recall the search results using the form on this page. TESS can also email results to you as a tab-delimited file suitable for loading into a spreadsheet program. Query for Transcription Factor Info: TESS also has data browsing and querying capabilities to help you learn about the factors that were predicted to bind to your sequence. Use the Query TRANSFAC or Query Matrices links above or use the search interface provided from the home page.
Proper citation: TESS: Transcription Element Search System (RRID:SCR_010739) Copy
http://mirtar.mbc.nctu.edu.tw/human/
An integrated web server for identifying miRNA-target interactions in human. The tool enables biologists easily to identify the biological functions and regulatory relationships between a group of known/putative miRNAs and protein coding genes. It also provides perspective of information on the miRNA targets on alternatively spliced transcripts.
Proper citation: miRTar (RRID:SCR_010851) Copy
http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-page+srsq2+-noSession
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. The EBI SRS server is a primary gateway to major databases in the field of molecular biology produced and supported at EBI as well as European public access point to the MEDLINE database provided by US National Library of Medicine (NLM). It is a reference server for latest developments in data and application integration. Features include: concept of virtual databases, integration of XML databases like the Integrated Resource of Protein Domains and Functional Sites (InterPro), Gene Ontology (GO), MEDLINE, Metabolic pathways, etc., user friendly data representation in ''Nice views'', SRSQuickSearch bookmarklets. Quick Searches allow users to make a number of searches without needing to learn how to use SRS in depth. The searches query some of the common databanks without having to go and select them explicitly and without the need to understand the SRS Query Forms. Quick Searches can be performed from either the Start page (when you first open SRS) or the SRS Quick Search page (when you are already in a project). SRS also has the ability to search for links between your current results and related information in other databanks. Additionally, it is able to analyze the results of your search using many bioinformatics analysis tools or applications. This enables you to seek out further information that may be relevant to your initial search.
Proper citation: SRS (RRID:SCR_010736) Copy
http://www.scienceexchange.com/facilities/emory-university
THIS RESOURCE IS NO LONGER IN SERVICE,documented on February 3rd,2022.
Proper citation: Emory University Labs and Facilities (RRID:SCR_011031) Copy
http://rth.dk/resources/rnasnp/
Software / Web Server to predict the effect of SNPs on local RNA secondary structure based on the RNA folding algorithms implemented in the Vienna RNA package.
Proper citation: RNAsnp (RRID:SCR_010837) Copy
http://www.scienceexchange.com/facilities/physiological-proteomics-core-facility-iu
THIS RESOURCE IS NO LONGER IN SERVCE, documented January 23, 2019. Facility enables researchers to identify and quantify proteins in simple or complex samples and characterize protein post-translational modifications or conjugates. PPCF provides the following mass spectrometry-based proteomics services: Protein Identification Protein Quantification Differential Protein Expression Analysis Protein Post-translational Modification Analysis Bioinformatics and Pathway Analysis Biomarker Discovery Please note, a set up fee is applied when the number of samples is less than 10.
Proper citation: Indiana University School of Medicine Physiological Proteomics Core Facility (RRID:SCR_011005) Copy
http://brainandsociety.org/the-brain-observatory
Formerly a topical portal studying the brain which collected and imaged 1000 human brains, the Brain Observatory has partnered with the Institute for Brain and Society to build virtual laboratories that will feed directly into the database of images and knowledge created in the context of the Human Brain Library. The Brain Observatory will also host exhibits, conferences, and events aimed at promoting a heightened awareness of brain research and how its results can benefit personal brain fitness and mental health.
Proper citation: Brain Observatory (RRID:SCR_010641) Copy
A web-based system for the detection of over-represented conserved transcription factor binding sites and binding site combinations in sets of genes or sequences.
Proper citation: oPOSSUM (RRID:SCR_010884) Copy
Tools for microarray quality control and pre-processing.
Proper citation: ArrayAnalysis.org (RRID:SCR_010932) Copy
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