On page 1 showing 1 ~ 14 out of 14 results
TBI Model Type: Blast model
Organism Species: pig
Organism Strain: No strain reported
Assessments: stress relaxation, Fractional Zener constitutive model, fractional Zener constitutive model, unconfined compression test
Citation: McCarty AK, Zhang L, Hansen S, Jackson WJ, Bentil SA. Viscoelastic properties of shock wave exposed brain tissue subjected to unconfined compression experimentsJ Mech Behav Biomed Mater. 2019 Dec;100:103380. doi: 10.1016\/j.jmbbm.2019.103380. Epub 2019 Aug 8.
TBI Model Type: Controlled cortical impact model
Organism Species: ferret
Organism Strain: No strain reported
Assessments: Diffusion tensor imaging(DTI), Immunohistochemistry (IHC), Magnetic resonance imaging (MRI), T2-weighted imaging
Citation: Hutchinson EB, Schwerin SC, Radomski KL, Irfanoglu MO, Juliano SL, Pierpaoli CM. Quantitative MRI and DTI Abnormalities During the Acute Period Following CCI in the FerretShock. 2016 Sep;46(3 Suppl 1):167-76. doi: 10.1097\/SHK.0000000000000659. PMC4978600
TBI Model Type: Controlled cortical impact model
Organism Species: pig
Organism Strain: No strain reported
Assessments: Histology, Immunohistochemistry (IHC), microdialysis
Citation: Kilbaugh TJ, Bhandare S, Lorom DH, Saraswati M, Robertson CL, Margulies SS. Cyclosporin A preserves mitochondrial function after traumatic brain injury in the immature rat and pigletJ Neurotrauma. 2011 May;28(5):763-74. doi: 10.1089\/neu.2010.1635. Epub 2011 Apr 12. PMC3125546
TBI Model Type: Weight-drop model
Organism Species: zebrafish
Organism Strain: No strain reported
Assessments: Learning, Glutamate Excitotoxicity, Immunoblot, Memory, qRT-PCR, ataxia, bending, circling, corkscrew swimming, clonic-seizure metrics, modified Puppala, Fluid Content Measurement
Citation: Hentig J, Campbell LJ, Cloghessy K, Lee M, Boggess W, Hyde DR. Prophylactic Activation of Shh Signaling Attenuates TBI-Induced Seizures in Zebrafish by Modulating Glutamate Excitotoxicity through Eaat2aBiomedicines. 2021 Dec 24;10(1):32. doi: 10.3390\/biomedicines10010032. PMC8773121
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: No strain reported
Assessments: immunofluorescence, Western blot
Citation: Cai Z, Zhu W, Zhao H, Yang P, Yang Y, Xu F. Dynamic Expression of Platelet-Derived Growth Factor-D and Phosphorylated Platelet-Derived Growth Factor Receptor-Β after Traumatic Brain Injury in RatsClin Lab. 2020 Nov 1;66(11). doi: 10.7754\/Clin.Lab.2020.200328.
TBI Model Type: Weight-drop model
Organism Species: zebrafish
Organism Strain: No strain reported
Assessments: Differential gene expression analysis, qRT-PCR, T-maze
Citation: Maheras AL, Dix B, Carmo OMS, Young AE, Gill VN, Sun JL, Booker AR, Thomason HA, Ibrahim AE, Stanislaw L, Dallego JC, Ngo CN, Chen A, Fortini BK, Spence RD. Genetic Pathways of Neuroregeneration in a Novel Mild Traumatic Brain Injury Model in Adult ZebrafisheNeuro. 2018 Jan 3;5(1):ENEURO.0208-17.2017. doi: 10.1523\/ENEURO.0208-17.2017. eCollection 2018 Jan-Feb. PMC5752677
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: No strain reported
Assessments: Evaluation scoring system, Evans blue extravasation, Malondialdehyde assay, Morris Water Maze (MWM), Western Blot
Citation: Wang M, Luo L. An Effective NADPH Oxidase 2 Inhibitor Provides Neuroprotection and Improves Functional Outcomes in Animal Model of Traumatic Brain InjuryNeurochem Res. 2020 May;45(5):1097-1106. doi: 10.1007\/s11064-020-02987-3. Epub 2020 Feb 18.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: No strain reported
Assessments: Immunohistochemistry (IHC)
Citation: Zhang Z, Zhang ZY, Wu Y, Schluesener HJ.Neuroimmunomodulation. 2012;19(1):10-9. doi: 10.1159/000326771. Epub 2011 Nov 7.
TBI Model Type: Controlled cortical impact model
Organism Species: ferret
Organism Strain: No strain reported
Assessments: Histology
Citation: Lighthall JW. Controlled cortical impact: a new experimental brain injury modelJ Neurotrauma. 1988;5(1):1-15. doi: 10.1089\/neu.1988.5.1.
TBI Model Type: Controlled cortical impact model
Organism Species: ferret
Organism Strain: No strain reported
Assessments: Histology
Citation: Lighthall JW, Goshgarian HG, Pinderski CR. Characterization of axonal injury produced by controlled cortical impactJ Neurotrauma. 1990 Summer;7(2):65-76. doi: 10.1089\/neu.1990.7.65.
TBI Model Type: Weight-drop model
Organism Species: zebrafish
Organism Strain: No strain reported
Assessments: Sonic Hedgehog Modulation, Evans Blue Assay, Fluid Content Measurement, Hoshi protocol, Image Acquisition, Immediate and Delayed Recall, Immunohistochemistry (IHC), Learning, Locomotion velocity, qRT-PCR, Sensorimotor Assay, Shuttle Box Assay Testing Apparatus, Startle Response Habituation, TUNEL staining, Vascular Injury, optical density, tonic-clonic seizure metrics
Citation: Hentig J, Cloghessy K, Lahne M, Jung YJ, Petersen RA, Morris AC, Hyde DR. Zebrafish Blunt-Force TBI Induces Heterogenous Injury Pathologies That Mimic Human TBI and Responds with Sonic Hedgehog-Dependent Cell Proliferation across the NeuroaxisBiomedicines. 2021 Jul 22;9(8):861. doi: 10.3390\/biomedicines9080861. PMC8389629
TBI Model Type: Controlled cortical impact model
Organism Species: ferret
Organism Strain: No strain reported
Assessments: Adhesive tape detection test, Gait, Immunohistochemistry (IHC), Magnetic resonance imaging (MRI), Novel object recognition test, Open field test
Citation: Schwerin SC, Hutchinson EB, Radomski KL, Ngalula KP, Pierpaoli CM, Juliano SL. Establishing the ferret as a gyrencephalic animal model of traumatic brain injury: Optimization of controlled cortical impact proceduresJ Neurosci Methods. 2017 Jun 15;285:82-96. doi: 10.1016\/j.jneumeth.2017.05.010. Epub 2017 May 10. PMC6320441
TBI Model Type: Other
Organism Species: pig
Organism Strain: No strain reported
Assessments: Histology, Immunohistochemistry (IHC), microdialysis
Citation: Kilbaugh TJ, Bhandare S, Lorom DH, Saraswati M, Robertson CL, Margulies SS. Cyclosporin A preserves mitochondrial function after traumatic brain injury in the immature rat and pigletJ Neurotrauma. 2011 May;28(5):763-74. doi: 10.1089\/neu.2010.1635. Epub 2011 Apr 12. PMC3125546
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: No strain reported
Assessments: Immunohistochemistry (IHC), Ladder walk, Neurological Severity Score (NSS), open field test, qRT-PCR, Western blot
Citation: Förstner P, Knöll B. Interference of neuronal activity-mediated gene expression through serum response factor deletion enhances mortality and hyperactivity after traumatic brain injuryFASEB J. 2020 Mar;34(3):3855-3873. doi: 10.1096\/fj.201902257RR. Epub 2020 Jan 12.
