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On page 1 showing 1 ~ 20 out of 47 results
Snippet Table

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Grip Test, Brain water content, Immunofluorescence, Immunohistochemistry (IHC), Mitochondrial MDA, SOD Content, Prussian Blue Staining, Reactive Oxygen Species Content, TUNEL staining, Western blot, dihydroethidium staining
Citation: Zhu Y, Wang H, Fang J, Dai W, Zhou J, Wang X, Zhou M. SS-31 Provides Neuroprotection by Reversing Mitochondrial Dysfunction after Traumatic Brain InjuryOxid Med Cell Longev. 2018 Aug 27;2018:4783602. doi: 10.1155\/2018\/4783602. eCollection 2018. PMC6129854

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: PCR, Western blot
Citation: Ji X, Zhang W, Zhang L, Zhang L, Zhang Y, Tang P. Inhibition of p21-activated kinase 1 by IPA-3 attenuates secondary injury after traumatic brain injury in miceBrain Res. 2014 Oct 17;1585:13-22. doi: 10.1016\/j.brainres.2014.08.026. Epub 2014 Aug 20.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Hematoxylin and Eosin, Immunohistochemistry (IHC)
Citation: Feng Y, Gao Y, Wang T, Tao L, Qiu S, Zhao X. A longitudinal study of the mechanical properties of injured brain tissue in a mouse modelJ Mech Behav Biomed Mater. 2017 Jul;71:407-415. doi: 10.1016\/j.jmbbm.2017.04.008. Epub 2017 Apr 8.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Glasgow Coma Scale, TUNEL staining, Immunohistochemistry (IHC)
Citation: Zhaba WD, Deji QZ, Gao SQ, Han YL, Gao CC, Deng HJ, Liu XL, Li T, Zhou ML. Deferoxamine reduces amyloid-beta peptides genesis and alleviates neural apoptosis after traumatic brain injuryNeuroreport. 2021 Apr 7;32(6):472-478. doi: 10.1097\/WNR.0000000000001619.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Spectrometer
Citation: Shochat A, Abookasis D. Differential effects of early postinjury treatment with neuroprotective drugs in a mouse model using diffuse reflectance spectroscopyNeurophotonics. 2015 Jan;2(1):015001. doi: 10.1117\/1.NPh.2.1.015001. Epub 2015 Jan 22. PMC4478758

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemistry, Novel object recognition test, Y-Maze, elevated plus maze test, staircase test
Citation: Qubty D, Rubovitch V, Benromano T, Ovadia M, Pick CG. Orally Administered Cinnamon Extract Attenuates Cognitive and Neuronal Deficits Following Traumatic Brain InjuryJ Mol Neurosci. 2021 Jan;71(1):178-186. doi: 10.1007\/s12031-020-01688-4. Epub 2020 Sep 8.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemistry (IHC), Western blot, spectrophotometer
Citation: Li X, Wang H, Gao Y, Li L, Tang C, Wen G, Yang Y, Zhuang Z, Zhou M, Mao L, Fan Y. Quercetin induces mitochondrial biogenesis in experimental traumatic brain injury via the PGC-1α signaling pathwayAm J Transl Res. 2016 Aug 15;8(8):3558-66. eCollection 2016. PMC5009408

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Cavalieri’s method, Hematoxylin and Eosin, Neurological Severity Score (NSS), ORT, Rotarod test, Western blot, Y Maze
Citation: Ji X, Peng D, Zhang Y, Zhang J, Wang Y, Gao Y, Lu N, Tang P. Astaxanthin improves cognitive performance in mice following mild traumatic brain injuryBrain Res. 2017 Mar 15;1659:88-95. doi: 10.1016\/j.brainres.2016.12.031. Epub 2016 Dec 31.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemistry (IHC), Nissl staining, Western blot, Brain water content, grip test, spectrophotometer, Neurological Severity Score (NSS)
Citation: Liang J, Wu S, Xie W, He H. Ketamine ameliorates oxidative stress-induced apoptosis in experimental traumatic brain injury via the Nrf2 pathwayDrug Des Devel Ther. 2018 Apr 16;12:845-853. doi: 10.2147\/DDDT.S160046. eCollection 2018. PMC5907785

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Immunohistochemistry (IHC), Nissl staining, Western blot, grip test, spectrophotometer
Citation: Fu C, Wang Q, Zhai X, Gao J. Sinomenine reduces neuronal cell apoptosis in mice after traumatic brain injury via its effect on mitochondrial pathwayDrug Des Devel Ther. 2018 Jan 5;12:77-84. doi: 10.2147\/DDDT.S154391. eCollection 2018. PMC5759853

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Western blot, X-ray
Citation: Rubovitch V, Shachar A, Werner H, Pick CG.Neurochem Int. 2011 Mar;58(4):443-6. doi: 10.1016/j.neuint.2011.01.009. Epub 2011 Jan 8.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Immunofluorescence, TUNEL staining, Western blot, spectrophotometer
Citation: Dai W, Wang H, Fang J, Zhu Y, Zhou J, Wang X, Zhou Y, Zhou M. Curcumin provides neuroprotection in model of traumatic brain injury via the Nrf2-ARE signaling pathwayBrain Res Bull. 2018 Jun;140:65-71. doi: 10.1016\/j.brainresbull.2018.03.020. Epub 2018 Apr 4.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Elevated Plus Maze, Novel Object Recognition, Western Blot
Citation: Rubovitch V, Pharayra A, Har-Even M, Dvir O, Mattson MP, Pick CG.Dietary Energy Restriction Ameliorates Cognitive Impairment in a Mouse Model of Traumatic Brain InjuryJ Mol Neurosci. 2019 Apr;67(4):613-621. doi: 10.1007/s12031-019-01271-6. Epub 2019 Feb 8.PMC658839710.1007/s12031-019-01271-6

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: TTC staining method, Current responses, Enzyme-linked immunosorbent assay, Nissl staining, brain water content, immunofluorescent staining, neurological severity score, wet and dry weight method
Citation: Zhai PP, Xu LH, Yang JJ, Jiang ZL, Zhao GW, Sun L, Wang GH, Li X.Reduction of inflammatory responses by L-serine treatment leads to neuroprotection in mice after traumatic brain injury.Neuropharmacology. 2015 Aug;95:1-11. doi: 10.1016/j.neuropharm.2015.02.026. Epub 2015 Mar 5.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Elevated Plus maze test, Novel Object Recognition task, Y maze test
Citation: Schreiber S, Lin R, Haim L, Baratz-Goldstien R, Rubovitch V, Vaisman N, Pick CG.Enriched environment improves the cognitive effects from traumatic brain injury in mice.Behav Brain Res. 2014 Sep 1;271:59-64. doi: 10.1016/j.bbr.2014.05.060. Epub 2014 Jun 4.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Evans blue (EB) extravasation, TUNEL assay, Western blot
Citation: Lu XY, Wang HD, Xu JG, Ding K, Li T.NADPH oxidase inhibition improves neurological outcome in experimental traumatic brain injury.Neurochem Int. 2014 Apr;69:14-9. doi: 10.1016/j.neuint.2014.02.006. Epub 2014 Feb 28.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Western blot
Citation: Lu XY, Wang HD, Xu JG, Ding K, Li T.Pretreatment with tert-butylhydroquinone attenuates cerebral oxidative stress in mice after traumatic brain injury.J Surg Res. 2014 May 1;188(1):206-12. doi: 10.1016/j.jss.2013.11.1106. Epub 2013 Dec 1.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Morris water maze (MWM), Hidden Platform, Novel object recognition (NOR), Y-Maze Test
Citation: Eakin K, Baratz-Goldstein R, Pick CG, Zindel O, Balaban CD, Hoffer ME, Lockwood M, Miller J, Hoffer BJ.Efficacy of N-acetyl cysteine in traumatic brain injury.PLoS One. 2014 Apr 16;9(4):e90617. doi: 10.1371/journal.pone.0090617. eCollection 2014.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: ELISA, EMSA, Immunohistochemistry (IHC), lactulose/mannitol (L/M) test, limulus amebocyte lysate (LAL) test
Citation: Jin W, Wang H, Ji Y, Hu Q, Yan W, Chen G, Yin H.Cytokine. 2008 Oct;44(1):135-40. doi: 10.1016/j.cyto.2008.07.005. Epub 2008 Aug 21.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: ELISA, TUNEL staining, Grip test, rt-PCR
Citation: Jin W, Wang H, Yan W, Zhu L, Hu Z, Ding Y, Tang K.J Neurotrauma. 2009 Jan;26(1):131-9. doi: 10.1089/neu.2008.0655.

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The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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