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On page 1 showing 1 ~ 8 out of 8 results
Snippet Table

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Coulter AcT 10 Hematology Analyzer, Enzyme-linked immunosorbent assay, Platelet aggregometry, Tail bleed times, Thromboelastometry, righting reflex response time
Citation: Martin GE, Xia B, Kim Y, Johnson MD, Veile R, Friend LA, Makley AT, Caldwell CC, Goodman MD. Platelet Function Changes in a Time-Dependent Manner Following Traumatic Brain Injury in a Murine ModelShock. 2018 Nov;50(5):551-556. doi: 10.1097\/SHK.0000000000001056.

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Immunofluorescence Staining, qRT-PCR
Citation: Morganti JM, Riparip LK, Rosi S.PLoS One. 2016 Jan 25;11(1):e0148001. doi: 10.1371/journal.pone.0148001. eCollection 2016.10.1371/journal.pone.0148001

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Hierarchical clustering analysis, Ingenuity Pathway Analysis, qRT-PCR
Citation: Morganti JM, Riparip LK, Chou A, Liu S, Gupta N, Rosi S.J Neuroinflammation. 2016 Apr 18;13(1):80. doi: 10.1186/s12974-016-0547-1.10.1186/s12974-016-0547-1

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Platelet Aggregation, Thromboelastometry, Western Blots
Citation: Martin GE, Pugh AM, Moran R, Veile R, Friend LA, Pritts TA, Makley AT, Caldwell CC, Goodman MD.Microvesicles generated following traumatic brain injury induce platelet dysfunction via adenosine diphosphate receptorJ Trauma Acute Care Surg. 2019 Apr;86(4):592-600. doi: 10.1097/TA.0000000000002171.PMC643350410.1097/TA.0000000000002171

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Flow Cytometry, Platelet Counts, Viscoelastic coagulation
Citation: Morris MC, John D, Singer KE, Moran R, McGlone E, Veile R, Goetzman HS, Makley AT, Caldwell CC, Goodman MD.Post-TBI splenectomy may exacerbate coagulopathy and platelet activation in a murine modelThromb Res. 2020 Sep;193:211-217. doi: 10.1016/j.thromres.2020.08.002. Epub 2020 Aug 7.PMC748410510.1016/j.thromres.2020.08.002

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Neuropsychiatric, Rotarod, forced swim test, immunohistochemistry
Citation: Niziolek GM, Boudreau RM, Baker J, Friend LA, Makley AT, Edwards MJ, Gulbins E, Goodman MD.Acid Sphingomyelinase Inhibition Mitigates Histopathological and Behavioral Changes in a Murine Model of Traumatic Brain InjuryJ Neurotrauma. 2020 Sep 1;37(17):1902-1909. doi: 10.1089/neu.2019.6436. Epub 2020 May 4.PMC748489510.1089/neu.2019.6436

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: CCX872 pharmacokinetic analysis, ELISA, fluorescent imaging, qRT-PCR, radial arm water maze
Citation: Morganti JM, Jopson TD, Liu S, Riparip LK, Guandique CK, Gupta N, Ferguson AR, Rosi S.J Neurosci. 2015 Jan 14;35(2):748-60. doi: 10.1523/JNEUROSCI.2405-14.2015.10.1523/JNEUROSCI.2405-14.2015

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Rotational Thromboelastometry
Citation: Morris MC, Kassam F, Bercz A, Beckmann N, Schumacher F, Gulbins E, Makley AT, Goodman MD.The Role of Chemoprophylactic Agents in Modulating Platelet Aggregability After Traumatic Brain InjuryJ Surg Res. 2019 Dec;244:1-8. doi: 10.1016/j.jss.2019.06.022. Epub 2019 Jul 3.PMC681570410.1016/j.jss.2019.06.022

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The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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