On page 1 showing 1 ~ 20 out of 43 results
TBI Model Type: Fluid percussion injury model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Western blot, optical density, qRT-PCR
Citation: Tian Y, Zhao R, Li X, Zhou J, Zhan D, Wang Y, He Y, Zhang J, Yuan H. Alterations of microRNAs expression profiles in small extracellular vesicle after traumatic brain injury in miceExp Anim. 2022 Mar 7. doi: 10.1538\/expanim.21-0148. Online ahead of print.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Evans blue extravasation, Neurological Severity Score (NSS), Novel object recognition test, Rotarod test, TUNEL staining, Western blot, lactate dehydrogenase release
Citation: Evanson NK, Guilhaume-Correa F, Herman JP, Goodman MD. Optic tract injury after closed head traumatic brain injury in mice: A model of indirect traumatic optic neuropathyPLoS One. 2018 May 10;13(5):e0197346. doi: 10.1371\/journal.pone.0197346. eCollection 2018. PMC5944994
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Hematoxylin and Eosin, Neurological Severity Score (NSS), Nissl staining, Timm stain
Citation: Ezaki J, Shimada R, Shibuya M, Kibayashi K. Hippocampal neuronal degeneration in the traumatic brain injury mouse: non-trivial effect of scalp incisionNeurol Res. 2016 Nov;38(11):994-1002. doi: 10.1080\/01616412.2016.1228746. Epub 2016 Sep 10.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Prussian blue staining, Cerebral blood flow, COIS imaging, Immunohistochemistry (IHC), seizure activity
Citation: Bouley J, Chung DY, Ayata C, Brown RH Jr, Henninger N. Cortical Spreading Depression Denotes Concussion InjuryJ Neurotrauma. 2019 Apr 1;36(7):1008-1017. doi: 10.1089\/neu.2018.5844. Epub 2018 Aug 24. PMC6444888
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Elevated plus maze, Forced swim test, Horizontal ladder beam, Immunohistochemistry (IHC), Morris Water Maze (MWM), Rotarod, Tail suspension test, Western Blots, optical fractionator probe
Citation: Gold EM, Vasilevko V, Hasselmann J, Tiefenthaler C, Hoa D, Ranawaka K, Cribbs DH, Cummings BJ. Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral DeficitsASN Neuro. 2018 Jan-Dec;10:1759091418781921. doi: 10.1177\/1759091418781921. PMC6050992
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Amyloid precursor protein, Cortical contusion volume, Immunoglobulin, Immunohistochemistry (IHC), Morris Water Maze (MWM), Neurological Severity Score (NSS), Neuroscore, Regional hippocampal neurodegeneration
Citation: Pleasant JM, Carlson SW, Mao H, Scheff SW, Yang KH, Saatman KE. Rate of neurodegeneration in the mouse controlled cortical impact model is influenced by impactor tip shape: implications for mechanistic and therapeutic studiesJ Neurotrauma. 2011 Nov;28(11):2245-62. doi: 10.1089\/neu.2010.1499. Epub 2011 Apr 21. PMC3218388
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Acoustic startle response, Body curl test, Elevated-plus maze, Forced swim test, Lesion volume, Morris Water Maze (MWM), open field test, prepulse inhibition
Citation: Washington PM, Forcelli PA, Wilkins T, Zapple DN, Parsadanian M, Burns MP. The effect of injury severity on behavior: a phenotypic study of cognitive and emotional deficits after mild, moderate, and severe controlled cortical impact injury in miceJ Neurotrauma. 2012 Sep;29(13):2283-96. doi: 10.1089\/neu.2012.2456. Epub 2012 Aug 3. PMC3430487
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: mean arterial blood pressure (MAP), Fluoro-Jade C staining (FJC), Hematoxylin and Eosin
Citation: Dennis AM, Haselkorn ML, Vagni VA, Garman RH, Janesko-Feldman K, Bayir H, Clark RS, Jenkins LW, Dixon CE, Kochanek PM. Hemorrhagic shock after experimental traumatic brain injury in mice: effect on neuronal deathJ Neurotrauma. 2009 Jun;26(6):889-99. doi: 10.1089\/neu.2008.0512. PMC2694227
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Fluoro-Jade C staining (FJC), Immunohistochemistry (IHC)
Citation: Hetzer SM, Shalosky EM, Torrens JN, Evanson NK. Chronic Histological Outcomes of Indirect Traumatic Optic Neuropathy in Adolescent Mice: Persistent Degeneration and Temporally Regulated Glial ResponsesCells. 2021 Nov 28;10(12):3343. doi: 10.3390\/cells10123343. PMC8699438
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Polyunsaturated Fatty Acids analysis, Sphingolipids analysis, Immunohistochemistry (IHC), Pavlovian fear conditioning, RT-PCR, Sphingomyelinase Assay, electroretinogram recording, open-field behavior assessment, optokinetic reflex measurement, tail suspension test
Citation: Mondal K, Takahashi H, Cole J 2nd, Del Mar NA, Li C, Stephenson DJ, Allegood J, Cowart LA, Chalfant CE, Reiner A, Mandal N. Systemic Elevation of n-3 Polyunsaturated Fatty Acids (n-3-PUFA) Is Associated with Protection against Visual, Motor, and Emotional Deficits in Mice following Closed-Head Mild Traumatic Brain InjuryMol Neurobiol. 2021 Nov;58(11):5564-5580. doi: 10.1007\/s12035-021-02501-y. Epub 2021 Aug 8. PMC8655834
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Image Acquisition, Western blot
Citation: Wang C, Shao C, Zhang L, Siedlak SL, Meabon JS, Peskind ER, Lu Y, Wang W, Perry G, Cook DG, Zhu X. Oxidative Stress Signaling in Blast TBI-Induced Tau PhosphorylationAntioxidants (Basel). 2021 Jun 15;10(6):955. doi: 10.3390\/antiox10060955. PMC8232162
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Cytokine Assay, Enzyme-linked immunosorbent assay (ELISA), Immunohistochemistry (IHC), astrocytic, hippocampal neurogenesis, microglia responses, radial arm water maze, Rotarod
Citation: Song S, Kong X, Acosta S, Sava V, Borlongan C, Sanchez-Ramos J. Granulocyte colony-stimulating factor promotes behavioral recovery in a mouse model of traumatic brain injuryJ Neurosci Res. 2016 May;94(5):409-23. doi: 10.1002\/jnr.23714. Epub 2016 Jan 29. PMC4805459
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Elevated plus maze, Forced swim test, Horizontal ladder beam, Immunohistochemistry (IHC), Morris Water Maze (MWM), Rotarod, Tail suspension test, Western Blots, optical fractionator probe
Citation: Gold EM, Vasilevko V, Hasselmann J, Tiefenthaler C, Hoa D, Ranawaka K, Cribbs DH, Cummings BJ. Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral DeficitsASN Neuro. 2018 Jan-Dec;10:1759091418781921. doi: 10.1177\/1759091418781921. PMC6050992
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Corticosterone Enzyme Assay, Novel object recognition test, OxiSelect Total Antioxidant Capacity Assay, Y Maze, immunoblot
Citation: Doulames VM, Vilcans M, Lee S, Shea TB. Social interaction attenuates the extent of secondary neuronal damage following closed head injury in miceFront Behav Neurosci. 2015 Oct 15;9:275. doi: 10.3389\/fnbeh.2015.00275. eCollection 2015. PMC4606018
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Histology, Morris Water Maze (MWM)
Citation: Shishido H, Kishimoto Y, Kawai N, Toyota Y, Ueno M, Kubota T, Kirino Y, Tamiya T. Traumatic brain injury accelerates amyloid-β deposition and impairs spatial learning in the triple-transgenic mouse model of Alzheimer's diseaseNeurosci Lett. 2016 Aug 26;629:62-67. doi: 10.1016\/j.neulet.2016.06.066. Epub 2016 Jun 29.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Beam walk test, Elevated plus maze, Forced swim test, Novel context mismatch test, open field test, qRT-PCR
Citation: Kahriman A, Bouley J, Bosco DA, Shazeeb MS, Henninger N. Differential association of baseline body weight and body-weight loss with neurological deficits, histology, and death after repetitive closed head traumatic brain injuryNeurosci Lett. 2022 Feb 6;771:136430. doi: 10.1016\/j.neulet.2021.136430. Epub 2021 Dec 29. PMC8821174
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Enzyme-linked immunosorbent assay (ELISA), GC-MS analysis, Metabolomic Analysis, Y-maze, discrimination index, Novel object recognition test, open field test
Citation: Alqahtani F, Assiri MA, Mohany M, Imran I, Javaid S, Rasool MF, Shakeel W, Sivandzade F, Alanazi AZ, Al-Rejaie SS, Alshammari MA, Alasmari F, Alanazi MM, Alamri FF. Coadministration of Ketamine and Perampanel Improves Behavioral Function and Reduces Inflammation in Acute Traumatic Brain Injury Mouse ModelBiomed Res Int. 2020 Dec 10;2020:3193725. doi: 10.1155\/2020\/3193725. eCollection 2020. PMC7749776
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Immunohistochemical, Tomography
Citation: Harper MM, Boehme N, Dutca LM, Anderson MG. The Retinal Ganglion Cell Response to Blast-Mediated Traumatic Brain Injury Is Genetic Background DependentInvest Ophthalmol Vis Sci. 2021 Jun 1;62(7):13. doi: 10.1167\/iovs.62.7.13. PMC8196410
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Enzyme-linked immunoassay, Open field test, Western blotting, biochemical, molecular
Citation: Sivandzade F, Alqahtani F, Sifat A, Cucullo L.The cerebrovascular and neurological impact of chronic smoking on post-traumatic brain injury outcome and recovery: an in vivo studyJ Neuroinflammation. 2020 Apr 27;17(1):133. doi: 10.1186/s12974-020-01818-0.PMC718471710.1186/s12974-020-01818-0
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Complete blood count, Quantifying fracture healing
Citation: Morioka K, Marmor Y, Sacramento JA, Lin A, Shao T, Miclau KR, Clark DR, Beattie MS, Marcucio RS, Miclau T 3rd, Ferguson AR, Bresnahan JC, Bahney CS.Sci Rep. 2019 Aug 21;9(1):12199. doi: 10.1038/s41598-019-48126-z.10.1038/s41598-019-48126-z