On page 1 showing 1 ~ 20 out of 249 results
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beam balance test, Morris Water Maze (MWM), Beam walk test
Citation: Dixon CE, Clifton GL, Lighthall JW, Yaghmai AA, Hayes RL. A controlled cortical impact model of traumatic brain injury in the ratJ Neurosci Methods. 1991 Oct;39(3):253-62. doi: 10.1016\/0165-0270(91)90104-8.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beam walk test, open field test, Five serial choice reaction time task, time-to-right
Citation: Mychasiuk R, Hehar H, Esser MJ. A mild traumatic brain injury (mTBI) induces secondary attention-deficit hyperactivity disorder-like symptomology in young ratsBehav Brain Res. 2015 Jun 1;286:285-92. doi: 10.1016\/j.bbr.2015.03.010. Epub 2015 Mar 11.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunohistochemistry (IHC), Zinc staining
Citation: Choi BY, Kim JH, Kim HJ, Lee BE, Kim IY, Sohn M, Suh SW. Zinc chelation reduces traumatic brain injury-induced neurogenesis in the subgranular zone of the hippocampal dentate gyrusJ Trace Elem Med Biol. 2014 Oct;28(4):474-81. doi: 10.1016\/j.jtemb.2014.07.007. Epub 2014 Aug 4.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Enzyme-linked immunosorbent assay (ELISA), Modified limb-placing, Western Blot, modified Voetsch neuroscore
Citation: Chang CZ, Wu SC, Kwan AL, Lin CL. Magnesium Lithospermate B Implicates 3'-5'-Cyclic Adenosine Monophosphate\/Protein Kinase A Pathway and N-Methyl-d-Aspartate Receptors in an Experimental Traumatic Brain InjuryWorld Neurosurg. 2015 Oct;84(4):954-63. doi: 10.1016\/j.wneu.2015.05.075. Epub 2015 Jun 18.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: qRT-PCR
Citation: Tang YL, Fang LJ, Zhong LY, Jiang J, Dong XY, Feng Z. Hub genes and key pathways of traumatic brain injury: bioinformatics analysis and in vivo validationNeural Regen Res. 2020 Dec;15(12):2262-2269. doi: 10.4103\/1673-5374.284996. PMC7749465
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar Albino
Assessments: Histology, Lowry method, Tissue Caspase-3, Tissue Glutathione Peroxidase, Tissue Malondialdehyde, Tissue Superoxide Dismutase
Citation: Özay R, Türkoğlu E, Gürer B, Dolgun H, Evirgen O, Ergüder Bİ, Hayırlı N, Gürses L, Şekerci Z, Yılmaz ER. Does Decorin Protect Neuronal Tissue via Its Antioxidant and Antiinflammatory Activity from Traumatic Brain Injury? An Experimental StudyWorld Neurosurg. 2017 Jan;97:407-415. doi: 10.1016\/j.wneu.2016.09.115. Epub 2016 Oct 12.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar Albino
Assessments: Histology, Lowry method, Tissue Caspase-3 Analysis, Tissue Glutathione Peroxidase Analysis, Tissue Malondialdehyde Analysis, Tissue Nitric Oxide Analysis, Tissue Superoxide Dismutase Analysis
Citation: Özay R, Türkoğlu ME, Gürer B, Dolgun H, Evirgen O, Ergüder Bİ, Hayırlı N, Gürses L, Şekerci Z. The Protective Effect of Omeprazole Against Traumatic Brain Injury: An Experimental StudyWorld Neurosurg. 2017 Aug;104:634-643. doi: 10.1016\/j.wneu.2017.04.136. Epub 2017 Apr 28.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Enzyme-linked immunosorbent assay (ELISA), level of homocysteine, qRT-PCR
Citation: Tommy T, Islam AA, Hatta M, Bukhari A, Nasrullah, Adhimarta W, Aminuddin, Zainuddin AA. Effect of folinic acid on serum homocysteine, TNFα, IL-10, and HMGB1 gene expression in head injury modelAnn Med Surg (Lond). 2021 Apr 6;65:102273. doi: 10.1016\/j.amsu.2021.102273. eCollection 2021 May. PMC8100092
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Harlan
Assessments: Beam balance test, Morris Water Maze (MWM), Beam task test, Beam walk test
Citation: Cheng JP, Shaw KE, Monaco CM, Hoffman AN, Sozda CN, Olsen AS, Kline AE. A relatively brief exposure to environmental enrichment after experimental traumatic brain injury confers long-term cognitive benefitsJ Neurotrauma. 2012 Nov 20;29(17):2684-8. doi: 10.1089\/neu.2012.2560. Epub 2012 Aug 27. PMC3510443
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Enzyme-linked immunosorbent assay, Immunohistochemistry (IHC), Neurological function, RT-PCR, Western blot, Differential gene expression analysis
Citation: Xiong LL, Hu Y, Zhang P, Zhang Z, Li LH, Gao GD, Zhou XF, Wang TH. Neural Stem Cell Transplantation Promotes Functional Recovery from Traumatic Brain Injury via Brain Derived Neurotrophic Factor-Mediated NeuroplasticityMol Neurobiol. 2018 Mar;55(3):2696-2711. doi: 10.1007\/s12035-017-0551-1. Epub 2017 Apr 18.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Morris Water Maze (MWM)
Citation: Adelson PD, Fellows-Mayle W, Kochanek PM, Dixon CE. Morris water maze function and histologic characterization of two age-at-injury experimental models of controlled cortical impact in the immature ratChilds Nerv Syst. 2013 Jan;29(1):43-53. doi: 10.1007\/s00381-012-1932-4. Epub 2012 Oct 23.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Wistar
Assessments: Neuron-Specific Enolase Light Immuno Assay
Citation: Woertgen C, Rothoerl RD, Brawanski A. Neuron-specific enolase serum levels after controlled cortical impact injury in the ratJ Neurotrauma. 2001 May;18(5):569-73. doi: 10.1089\/089771501300227378.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Image analysis, Morris Water Maze (MWM)
Citation: Barot J, Saxena B. Therapeutic effects of eugenol in a rat model of traumatic brain injury: A behavioral, biochemical, and histological studyJ Tradit Complement Med. 2021 Jan 8;11(4):318-327. doi: 10.1016\/j.jtcme.2021.01.003. eCollection 2021 Jul. PMC8240337
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Enzyme-linked immunosorbent assay (ELISA), Elevated plus maze, Immunofluorescence, open field test, TUNEL staining, Western blot
Citation: Xie LL, Li SS, Fan YJ, Qi MM, Li ZZ. Melatonin alleviates traumatic brain injury-induced anxiety-like behaviors in rats: Roles of the protein kinase A\/cAMP-response element binding signaling pathwayExp Ther Med. 2022 Apr;23(4):248. doi: 10.3892\/etm.2022.11173. Epub 2022 Jan 31. PMC8855513
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: EEG/EMG recording, Neurological Severity Score (NSS), Novel object recognition test, open field test, Hematoxylin and Eosin, Immunofluorescence, uniaxial accelerometer
Citation: Büchele F, Morawska MM, Schreglmann SR, Penner M, Muser M, Baumann CR, Noain D. Novel Rat Model of Weight Drop-Induced Closed Diffuse Traumatic Brain Injury Compatible with Electrophysiological Recordings of Vigilance StatesJ Neurotrauma. 2016 Jul 1;33(13):1171-80. doi: 10.1089\/neu.2015.4001. Epub 2015 Nov 13.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Immunohistochemistry (IHC), Magnetic resonance imaging (MRI)
Citation: Tu TW, Lescher JD, Williams RA, Jikaria N, Turtzo LC, Frank JA. Abnormal Injury Response in Spontaneous Mild Ventriculomegaly Wistar Rat Brains: A Pathological Correlation Study of Diffusion Tensor and Magnetization Transfer Imaging in Mild Traumatic Brain InjuryJ Neurotrauma. 2017 Jan 1;34(1):248-256. doi: 10.1089\/neu.2015.4355. Epub 2016 Apr 11. PMC5198143
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunohistochemistry (IHC), Morris Water Maze (MWM), Neurological Severity Score (NSS), Western blot, Brain water content
Citation: Cui CM, Gao JL, Cui Y, Sun LQ, Wang YC, Wang KJ, Li R, Tian YX, Cui JZ. Chloroquine exerts neuroprotection following traumatic brain injury via suppression of inflammation and neuronal autophagic deathMol Med Rep. 2015 Aug;12(2):2323-8. doi: 10.3892\/mmr.2015.3611. Epub 2015 Apr 15.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Long-Evans
Assessments: open field test, Corticosterone level, Novel object recognition test, foot fault test, NeuN staining, Cresyl violet staining
Citation: Jamnia N, Urban JH, Stutzmann GE, Chiren SG, Reisenbigler E, Marr R, Peterson DA, Kozlowski DA. A Clinically Relevant Closed-Head Model of Single and Repeat Concussive Injury in the Adult Rat Using a Controlled Cortical Impact DeviceJ Neurotrauma. 2017 Apr 1;34(7):1351-1363. doi: 10.1089\/neu.2016.4517. Epub 2016 Dec 2.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wister
Assessments: Enzyme-linked immunosorbent assay (ELISA), Hematoxylin and Eosin, RT-PCR, Western blot, permeability assay
Citation: Lang Y, Fu F, Sun D, Xi C, Chen F. Labetalol Prevents Intestinal Dysfunction Induced by Traumatic Brain InjuryPLoS One. 2015 Jul 17;10(7):e0133215. doi: 10.1371\/journal.pone.0133215. eCollection 2015. PMC4505891
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar–Kyoto
Assessments: BK channel current, CM-H2DCFDA staining, qRT-PCR, pressure myography
Citation: Szarka N, Pabbidi MR, Amrein K, Czeiter E, Berta G, Pohoczky K, Helyes Z, Ungvari Z, Koller A, Buki A, Toth P. Traumatic Brain Injury Impairs Myogenic Constriction of Cerebral Arteries: Role of Mitochondria-Derived H(2)O(2) and TRPV4-Dependent Activation of BK(ca) ChannelsJ Neurotrauma. 2018 Apr 1;35(7):930-939. doi: 10.1089\/neu.2017.5056. Epub 2018 Jan 12. PMC5865628
