On page 1 showing 1 ~ 20 out of 39 results
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beam balance test, Morris Water Maze (MWM), Beam walk test
Citation: Dixon CE, Clifton GL, Lighthall JW, Yaghmai AA, Hayes RL. A controlled cortical impact model of traumatic brain injury in the ratJ Neurosci Methods. 1991 Oct;39(3):253-62. doi: 10.1016\/0165-0270(91)90104-8.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Harlan
Assessments: Beam balance test, Morris Water Maze (MWM), Beam task test, Beam walk test
Citation: Cheng JP, Shaw KE, Monaco CM, Hoffman AN, Sozda CN, Olsen AS, Kline AE. A relatively brief exposure to environmental enrichment after experimental traumatic brain injury confers long-term cognitive benefitsJ Neurotrauma. 2012 Nov 20;29(17):2684-8. doi: 10.1089\/neu.2012.2560. Epub 2012 Aug 27. PMC3510443
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Morris Water Maze (MWM)
Citation: Adelson PD, Fellows-Mayle W, Kochanek PM, Dixon CE. Morris water maze function and histologic characterization of two age-at-injury experimental models of controlled cortical impact in the immature ratChilds Nerv Syst. 2013 Jan;29(1):43-53. doi: 10.1007\/s00381-012-1932-4. Epub 2012 Oct 23.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Image analysis, Morris Water Maze (MWM)
Citation: Barot J, Saxena B. Therapeutic effects of eugenol in a rat model of traumatic brain injury: A behavioral, biochemical, and histological studyJ Tradit Complement Med. 2021 Jan 8;11(4):318-327. doi: 10.1016\/j.jtcme.2021.01.003. eCollection 2021 Jul. PMC8240337
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunohistochemistry (IHC), Morris Water Maze (MWM), Neurological Severity Score (NSS), Western blot, Brain water content
Citation: Cui CM, Gao JL, Cui Y, Sun LQ, Wang YC, Wang KJ, Li R, Tian YX, Cui JZ. Chloroquine exerts neuroprotection following traumatic brain injury via suppression of inflammation and neuronal autophagic deathMol Med Rep. 2015 Aug;12(2):2323-8. doi: 10.3892\/mmr.2015.3611. Epub 2015 Apr 15.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL
Assessments: Histology, Morris Water Maze (MWM)
Citation: Smith DH, Soares HD, Pierce JS, Perlman KG, Saatman KE, Meaney DF, Dixon CE, McIntosh TK. A model of parasagittal controlled cortical impact in the mouse: cognitive and histopathologic effectsJ Neurotrauma. 1995 Apr;12(2):169-78. doi: 10.1089\/neu.1995.12.169.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: flow cytometry, ATP detection, Bradford method, Hematoxylin and eosin, Immunofluorescence, L-lactate assay kit, Morris Water Maze (MWM)
Citation: Dong T, Zhang Q, Hamblin MR, Wu MX. Low-level light in combination with metabolic modulators for effective therapy of injured brainJ Cereb Blood Flow Metab. 2015 Sep;35(9):1435-44. doi: 10.1038\/jcbfm.2015.87. Epub 2015 May 13. PMC4640344
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Elevated plus maze, Forced swim test, Horizontal ladder beam, Immunohistochemistry (IHC), Morris Water Maze (MWM), Rotarod, Tail suspension test, Western Blots, optical fractionator probe
Citation: Gold EM, Vasilevko V, Hasselmann J, Tiefenthaler C, Hoa D, Ranawaka K, Cribbs DH, Cummings BJ. Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral DeficitsASN Neuro. 2018 Jan-Dec;10:1759091418781921. doi: 10.1177\/1759091418781921. PMC6050992
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6-SJLF1
Assessments: Conditioned fear testing, Morris Water Maze (MWM), Rotorod test, Histology, shock sensitivity testing
Citation: Brody DL, Mac Donald C, Kessens CC, Yuede C, Parsadanian M, Spinner M, Kim E, Schwetye KE, Holtzman DM, Bayly PV. Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injuryJ Neurotrauma. 2007 Apr;24(4):657-73. doi: 10.1089\/neu.2006.0011. PMC2435168
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Amyloid precursor protein, Cortical contusion volume, Immunoglobulin, Immunohistochemistry (IHC), Morris Water Maze (MWM), Neurological Severity Score (NSS), Neuroscore, Regional hippocampal neurodegeneration
Citation: Pleasant JM, Carlson SW, Mao H, Scheff SW, Yang KH, Saatman KE. Rate of neurodegeneration in the mouse controlled cortical impact model is influenced by impactor tip shape: implications for mechanistic and therapeutic studiesJ Neurotrauma. 2011 Nov;28(11):2245-62. doi: 10.1089\/neu.2010.1499. Epub 2011 Apr 21. PMC3218388
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Acoustic startle response, Body curl test, Elevated-plus maze, Forced swim test, Lesion volume, Morris Water Maze (MWM), open field test, prepulse inhibition
Citation: Washington PM, Forcelli PA, Wilkins T, Zapple DN, Parsadanian M, Burns MP. The effect of injury severity on behavior: a phenotypic study of cognitive and emotional deficits after mild, moderate, and severe controlled cortical impact injury in miceJ Neurotrauma. 2012 Sep;29(13):2283-96. doi: 10.1089\/neu.2012.2456. Epub 2012 Aug 3. PMC3430487
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, Morris Water Maze (MWM), Neurologic Deficit Scoring, Western Blot, Novel object recognition test, RT-PCR
Citation: Cheng T, Yang B, Li D, Ma S, Tian Y, Qu R, Zhang W, Zhang Y, Hu K, Guan F, Wang J. Wharton's Jelly Transplantation Improves Neurologic Function in a Rat Model of Traumatic Brain InjuryCell Mol Neurobiol. 2015 Jul;35(5):641-9. doi: 10.1007\/s10571-015-0159-9. Epub 2015 Feb 1. PMC4481175
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Elevated plus maze, Forced swim test, Horizontal ladder beam, Immunohistochemistry (IHC), Morris Water Maze (MWM), Rotarod, Tail suspension test, Western Blots, optical fractionator probe
Citation: Gold EM, Vasilevko V, Hasselmann J, Tiefenthaler C, Hoa D, Ranawaka K, Cribbs DH, Cummings BJ. Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral DeficitsASN Neuro. 2018 Jan-Dec;10:1759091418781921. doi: 10.1177\/1759091418781921. PMC6050992
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Histology, Morris Water Maze (MWM)
Citation: Shishido H, Kishimoto Y, Kawai N, Toyota Y, Ueno M, Kubota T, Kirino Y, Tamiya T. Traumatic brain injury accelerates amyloid-β deposition and impairs spatial learning in the triple-transgenic mouse model of Alzheimer's diseaseNeurosci Lett. 2016 Aug 26;629:62-67. doi: 10.1016\/j.neulet.2016.06.066. Epub 2016 Jun 29.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ELISA, Beam walk test, Morris water maze (MWM), Western blot, Immunohistochemistry (IHC)
Citation: Tian L, Guo R, Yue X, Lv Q, Ye X, Wang Z, Chen Z, Wu B, Xu G, Liu X.Brain Res. 2012 Feb 27;1440:47-55. doi: 10.1016/j.brainres.2011.12.059. Epub 2012 Jan 8.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Enzyme-linked immunosorbent assay (ELISA), Morris Water Maze (MWM)
Citation: Luo ML, Pan L, Wang L, Wang HY, Li S, Long ZY, Zeng L, Liu Y. Transplantation of NSCs Promotes the Recovery of Cognitive Functions by Regulating Neurotransmitters in Rats with Traumatic Brain InjuryNeurochem Res. 2019 Dec;44(12):2765-2775. doi: 10.1007\/s11064-019-02897-z. Epub 2019 Nov 7.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: No strain reported
Assessments: Evaluation scoring system, Evans blue extravasation, Malondialdehyde assay, Morris Water Maze (MWM), Western Blot
Citation: Wang M, Luo L. An Effective NADPH Oxidase 2 Inhibitor Provides Neuroprotection and Improves Functional Outcomes in Animal Model of Traumatic Brain InjuryNeurochem Res. 2020 May;45(5):1097-1106. doi: 10.1007\/s11064-020-02987-3. Epub 2020 Feb 18.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Catalase (CAT) Assay, Glutathione Peroxidase (GSH-Px) Activity, Morris water maze (MWM), Superoxide dismutase analysis, Terminal Dexynucleotidyl Transferase (TdT)-Mediated dUTP Nick End Labeling (TUNEL) Assay, Thiobarbituric Acid Reactive Substances (TBARS) Levels, Western Blot, Colorimetric kit
Citation: Yang T, Kong B, Gu JW, Kuang YQ, Cheng L, Yang WT, Xia X, Shu HF.Anti-apoptotic and anti-oxidative roles of quercetin after traumatic brain injury.Cell Mol Neurobiol. 2014 Aug;34(6):797-804. doi: 10.1007/s10571-014-0070-9. Epub 2014 May 21.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Morris water maze (MWM), qRT-PCR, Immunofluorescence staining, terminal deoxynucleotidyl transferase-mediated dUTP nick 3-end labeling
Citation: Liu S, Zhang L, Wu Q, Wu Q, Wang T.Chemokine CCL2 induces apoptosis in cortex following traumatic brain injury.J Mol Neurosci. 2013 Nov;51(3):1021-9. doi: 10.1007/s12031-013-0091-8. Epub 2013 Aug 11.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Morris water maze (MWM), Hidden Platform, Novel object recognition (NOR), Y-Maze Test
Citation: Eakin K, Baratz-Goldstein R, Pick CG, Zindel O, Balaban CD, Hoffer ME, Lockwood M, Miller J, Hoffer BJ.Efficacy of N-acetyl cysteine in traumatic brain injury.PLoS One. 2014 Apr 16;9(4):e90617. doi: 10.1371/journal.pone.0090617. eCollection 2014.
