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On page 1 showing 1 ~ 20 out of 33 results
Snippet Table

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemistry, Novel object recognition test, Y-Maze, elevated plus maze test, staircase test
Citation: Qubty D, Rubovitch V, Benromano T, Ovadia M, Pick CG. Orally Administered Cinnamon Extract Attenuates Cognitive and Neuronal Deficits Following Traumatic Brain InjuryJ Mol Neurosci. 2021 Jan;71(1):178-186. doi: 10.1007\/s12031-020-01688-4. Epub 2020 Sep 8.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Error ladder test, Histology, Novel objective recognition (NOR) test, Sticky tape test, Western blotting, immunohistochemistry, novel object recognition
Citation: Zakarya R, Sapkota A, Chan YL, Shah J, Saad S, Bottle SE, Oliver BG, Gorrie CA, Chen H.Nitroxides affect neurological deficits and lesion size induced by a rat model of traumatic brain injuryNitric Oxide. 2020 Apr 1;97:57-65. doi: 10.1016/j.niox.2020.02.001. Epub 2020 Feb 13.10.1016/j.niox.2020.02.001

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Long Evans
Assessments: ELISA test, Immunohistochemistry, Morris water maze test, Novel object recognition test, open field test
Citation: Tadepalli SA, Bali ZK, Bruszt N, Nagy LV, Amrein K, Fazekas B, Büki A, Czeiter E, Hernádi I.Long-term cognitive impairment without diffuse axonal injury following repetitive mild traumatic brain injury in ratsBehav Brain Res. 2020 Jan 27;378:112268. doi: 10.1016/j.bbr.2019.112268. Epub 2019 Sep 30.10.1016/j.bbr.2019.112268

TBI Model Type: Fluid percussion injury model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Immunohistochemistry, Neurological Severity Score, Olmos amino cupric silver (Ag) technique, Rotarod, Sleep recordings, forced swim task, morphology analysis, novel object recognition, open field task
Citation: Rowe RK, Harrison JL, Morrison HW, Subbian V, Murphy SM, Lifshitz J.J Neurotrauma. 2019 Apr 15;36(8):1318-1334. doi: 10.1089/neu.2018.5980. Epub 2018 Dec 18.10.1089/neu.2018.5980

Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ELISA, Immunohistochemistry, LICOR imaging, Novel object recognition, Open field test, novel object placement memory tests, western blot analysis
Citation: Delic V, Karp JH, Guzman M, Arismendi GR, Stalnaker KJ, Burton JA, Murray KE, Stamos JP, Beck KD, Sokratian A, West AB, Citron BA.Acta Neuropathol Commun. 2022 Nov 26;10(1):170. doi: 10.1186/s40478-022-01475-9.10.1186/s40478-022-01475-9

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Malondialdehyde and glutathione peroxidase ­ assays, Immunohistochemistry, haematoxylin, superoxide dismutase activity, catalase activity, Statistical analysis
Citation: Çetin A, Deveci E.Evaluation of PECAM-1 and p38 MAPK expressions in cerebellum tissue of rats treated with caffeic acid phenethyl ester: a biochemical and immunohistochemical studyFolia Morphol (Warsz). 2019;78(2):221-229. doi: 10.5603/FM.a2018.0085. Epub 2018 Dec 13.10.5603/FM.a2018.0085

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague Dawley
Assessments: ELISA, Immunohistochemistry
Citation: Dhir T, Weiss E, Wolanin K, Randhawa S, Samuel S, Minimo C, Becker G, McGreen B, Kriza C, Patel N, Kaplan M, Leung P.The impact of enoxaparin administration in relationship to hemorrhage in mild traumatic brain injuryInjury. 2018 Dec;49(12):2174-2177. doi: 10.1016/j.injury.2018.09.027. Epub 2018 Sep 14.10.1016/j.injury.2018.09.027

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: ELISA, Neurological Severity Score, TUNEL histochemistry, immunohistochemistry, real-time RT-PCR
Citation: Leinhase I, Rozanski M, Harhausen D, Thurman JM, Schmidt OI, Hossini AM, Taha ME, Rittirsch D, Ward PA, Holers VM, Ertel W, Stahel PF.Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in miceJ Neuroinflammation. 2007 May 2;4:13. doi: 10.1186/1742-2094-4-13.PMC186780810.1186/1742-2094-4-13

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Flow Cytometry, Immunohistochemistry, hematoxylin and eosin
Citation: Lee J, Costantini TW, D'Mello R, Eliceiri BP, Coimbra R, Bansal V.Altering leukocyte recruitment following traumatic brain injury with ghrelin therapy.J Trauma Acute Care Surg. 2014 Nov;77(5):709-715. doi: 10.1097/TA.0000000000000445.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Image Analysis, Immunohistochemistry, Image Analysis, Immunohistochemistry
Citation: Sköld MK, von Gertten C, Sandberg-Nordqvist AC, Mathiesen T, Holmin S.VEGF and VEGF receptor expression after experimental brain contusion in ratJ Neurotrauma. 2005 Mar;22(3):353-67. doi: 10.1089/neu.2005.22.353.10.1089/neu.2005.22.353

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Lewis
Assessments: Immunohistochemistry
Citation: Liu Y, Liu Z, Li X, Luo B, Xiong J, Gan W, Jiang M, Zhang Z, Schluesener HJ, Zhang Z.Accumulation of connective tissue growth factor+ cells during the early phase of rat traumatic brain injury.Diagn Pathol. 2014 Jul 10;9:141. doi: 10.1186/1746-1596-9-141.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawle
Assessments: Immunohistochemistry, Microtubule-Associated Protein, Morris Water Maze
Citation: Marklund N, Clausen F, Lewén A, Hovda DA, Olsson Y, Hillered L.alpha-Phenyl-tert-N-butyl nitrone (PBN) improves functional and morphological outcome after cortical contusion injury in the ratActa Neurochir (Wien). 2001;143(1):73-81. doi: 10.1007/s007010170141.10.1007/s007010170141

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague–Dawley
Assessments: BBB permeability, ELISA, Electron microscopy, Gravimetric analysis, Neurochemical assays, Nissl staining, Western blot analysis, beam-balancing test, immunohistochemistry
Citation: Wang GH, Jiang ZL, Li YC, Li X, Shi H, Gao YQ, Vosler PS, Chen J.Free-radical scavenger edaravone treatment confers neuroprotection against traumatic brain injury in ratsJ Neurotrauma. 2011 Oct;28(10):2123-34. doi: 10.1089/neu.2011.1939. Epub 2011 Sep 27.PMC319136810.1089/neu.2011.1939

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain water content, M29, 79-dichlorodihydrofluorescein diacetate (DCFH-DA) staining, Morris Water Maze, Neurological Severity Scores, Nissl staining, TdT-mediated dUTP Nick-End Labeling, We performed modified Neurological Severity Scores (mNSS), rotarod test, and Morris Water Maze (MWM) test, respectively (n = 8 for each group), enzyme linked immunosorbent assay, immunofluorescence, immunohistochemistry, quantitative real time polymerase chain reaction, rotarod test, western blot
Citation: Wang H, Zhou XM, Wu LY, Liu GJ, Xu WD, Zhang XS, Gao YY, Tao T, Zhou Y, Lu Y, Wang J, Deng CL, Zhuang Z, Hang CH, Li W.Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injuryJ Neuroinflammation. 2020 Jun 15;17(1):188. doi: 10.1186/s12974-020-01863-9.PMC729463110.1186/s12974-020-01863-9

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Neuropsychiatric, Rotarod, forced swim test, immunohistochemistry
Citation: Niziolek GM, Boudreau RM, Baker J, Friend LA, Makley AT, Edwards MJ, Gulbins E, Goodman MD.Acid Sphingomyelinase Inhibition Mitigates Histopathological and Behavioral Changes in a Murine Model of Traumatic Brain InjuryJ Neurotrauma. 2020 Sep 1;37(17):1902-1909. doi: 10.1089/neu.2019.6436. Epub 2020 May 4.PMC748489510.1089/neu.2019.6436

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Behavioral, Elevated Plus Maze Paradigm, Fluoro Jade B, Immunohistochemistry, Novel Object Recognition Paradigm, Western Blotting, Y-Maze Paradigm, glial fibrillary acidic protein, neuronal nuclear antigen
Citation: Bader M, Li Y, Tweedie D, Shlobin NA, Bernstein A, Rubovitch V, Tovar-Y-Romo LB, DiMarchi RD, Hoffer BJ, Greig NH, Pick CG.Neuroprotective Effects and Treatment Potential of Incretin Mimetics in a Murine Model of Mild Traumatic Brain InjuryFront Cell Dev Biol. 2020 Jan 10;7:356. doi: 10.3389/fcell.2019.00356. eCollection 2019.PMC696503110.3389/fcell.2019.00356

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Bederson test, Evans blue fluorescence, MRI, Perls staining, TUNEL, Western blot, behavioral, brain water content, enzyme-linked immunosorbent assay, immunohistochemistry, magnetic resonance imaging, myelin basic protein (MBP) expression, quantitative real-time PCR
Citation: Wei L, Zhang J, Zhang B, Geng J, Tan Q, Wang L, Chen Z, Feng H, Zhu G.Complement C3 participates in the function and mechanism of traumatic brain injury at simulated high altitudeBrain Res. 2020 Jan 1;1726:146423. doi: 10.1016/j.brainres.2019.146423. Epub 2019 Oct 22.10.1016/j.brainres.2019.146423

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain Water, H & E stain, Immunofluorescence, Immunohistochemistry, Western Blot
Citation: Yi HJ, Lee JE, Lee DH, Kim YI, Cho CB, Kim IS, Sung JH, Yang SH.The role of NLRP3 in traumatic brain injury and its regulation by pioglitazoneJ Neurosurg. 2019 Sep 27;133(4):1083-1091. doi: 10.3171/2019.6.JNS1954. Print 2020 Oct 1.10.3171/2019.6.JNS1954

Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Electrophysiology, Elevated plus maze, Immunohistochemistry, Magnetic resonance image, modified Barnes maze, three-chamber social approach task
Citation: Nolan A, Hennessy E, Krukowski K, Guglielmetti C, Chaumeil MM, Sohal VS, Rosi S.J Neurotrauma. 2018 Oct 15;35(20):2425-2434. doi: 10.1089/neu.2018.5731. Epub 2018 Jul 2.10.1089/neu.2018.5731

TBI Model Type: Fluid percussion injury model
Organism Species: rat
Organism Strain: Long-Evans
Assessments: Caspase activity assays, Cavalieri probe method, Conditioned freezing response test, Counting APC-positive cells, Counting NeuN-positive cells, Histology, Immunohistochemistry, Object recognition test, Quantification of TrkA phosphorylation, Western blot analysis, cell counts, immunocytochemistry, kainate sensitivity test, microglia activation, myelin loss, paw placement test
Citation: Delbary-Gossart S, Lee S, Baroni M, Lamarche I, Arnone M, Canolle B, Lin A, Sacramento J, Salegio EA, Castel MN, Delesque-Touchard N, Alam A, Laboudie P, Ferzaz B, Savi P, Herbert JM, Manley GT, Ferguson AR, Bresnahan JC, Bono F, Beattie MS.Brain. 2016 Jun;139(Pt 6):1762-82. doi: 10.1093/brain/aww074. Epub 2016 Apr 15.10.1093/brain/aww074


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