On page 1 showing 1 ~ 20 out of 47 results
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Grip Test, Brain water content, Immunofluorescence, Immunohistochemistry (IHC), Mitochondrial MDA, SOD Content, Prussian Blue Staining, Reactive Oxygen Species Content, TUNEL staining, Western blot, dihydroethidium staining
Citation: Zhu Y, Wang H, Fang J, Dai W, Zhou J, Wang X, Zhou M. SS-31 Provides Neuroprotection by Reversing Mitochondrial Dysfunction after Traumatic Brain InjuryOxid Med Cell Longev. 2018 Aug 27;2018:4783602. doi: 10.1155\/2018\/4783602. eCollection 2018. PMC6129854
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Enzyme-linked immunosorbent assay (ELISA), Elevated plus maze, Immunofluorescence, open field test, TUNEL staining, Western blot
Citation: Xie LL, Li SS, Fan YJ, Qi MM, Li ZZ. Melatonin alleviates traumatic brain injury-induced anxiety-like behaviors in rats: Roles of the protein kinase A\/cAMP-response element binding signaling pathwayExp Ther Med. 2022 Apr;23(4):248. doi: 10.3892\/etm.2022.11173. Epub 2022 Jan 31. PMC8855513
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: EEG/EMG recording, Neurological Severity Score (NSS), Novel object recognition test, open field test, Hematoxylin and Eosin, Immunofluorescence, uniaxial accelerometer
Citation: Büchele F, Morawska MM, Schreglmann SR, Penner M, Muser M, Baumann CR, Noain D. Novel Rat Model of Weight Drop-Induced Closed Diffuse Traumatic Brain Injury Compatible with Electrophysiological Recordings of Vigilance StatesJ Neurotrauma. 2016 Jul 1;33(13):1171-80. doi: 10.1089\/neu.2015.4001. Epub 2015 Nov 13.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: flow cytometry, ATP detection, Bradford method, Hematoxylin and eosin, Immunofluorescence, L-lactate assay kit, Morris Water Maze (MWM)
Citation: Dong T, Zhang Q, Hamblin MR, Wu MX. Low-level light in combination with metabolic modulators for effective therapy of injured brainJ Cereb Blood Flow Metab. 2015 Sep;35(9):1435-44. doi: 10.1038\/jcbfm.2015.87. Epub 2015 May 13. PMC4640344
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: Swiss Albino
Assessments: Immunofluorescence, modified Neurological Severity Score (mNSS)
Citation: Karakaya D, Cakir-Aktas C, Uzun S, Soylemezoglu F, Mut M. Tailored Therapeutic Doses of Dexmedetomidine in Evolving Neuroinflammation after Traumatic Brain InjuryNeurocrit Care. 2022 Jun;36(3):802-814. doi: 10.1007\/s12028-021-01381-3. Epub 2021 Nov 16.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Evans blue permeability assay, Immunofluorescence staining, TUNEL staining, Western blot, Immunofluorescence, modified Neurological Severity Score (mNSS)
Citation: Li H, Sun J, Du J, Wang F, Fang R, Yu C, Xiong J, Chen W, Lu Z, Liu J. Clostridium butyricum exerts a neuroprotective effect in a mouse model of traumatic brain injury via the gut-brain axisNeurogastroenterol Motil. 2018 May;30(5):e13260. doi: 10.1111\/nmo.13260. Epub 2017 Nov 27.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: No strain reported
Assessments: immunofluorescence, Western blot
Citation: Cai Z, Zhu W, Zhao H, Yang P, Yang Y, Xu F. Dynamic Expression of Platelet-Derived Growth Factor-D and Phosphorylated Platelet-Derived Growth Factor Receptor-Β after Traumatic Brain Injury in RatsClin Lab. 2020 Nov 1;66(11). doi: 10.7754\/Clin.Lab.2020.200328.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ATP Assay, Behavioral Testing, Activity score, Brain water content, Fluoro-jade C staining (FJC), Immunofluorescence, Neurological score, RT-PCR, TUNEL staining, Western blot
Citation: Chen C, Lu L, Zhu J, Gu X, Liu B, Li D, Chen G. Miro1 provides neuroprotection via the mitochondrial trafficking pathway in a rat model of traumatic brain injuryBrain Res. 2021 Dec 15;1773:147685. doi: 10.1016\/j.brainres.2021.147685. Epub 2021 Oct 9.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Hang test, Immunofluorescence, Nissl staining, Western blot, tail suspension test
Citation: Selvakumar GP, Ahmed ME, Iyer SS, Thangavel R, Kempuraj D, Raikwar SP, Bazley K, Wu K, Khan A, Kukulka K, Bussinger B, Zaheer S, Burton C, James D, Zaheer A. Absence of Glia Maturation Factor Protects from Axonal Injury and Motor Behavioral Impairments after Traumatic Brain InjuryExp Neurobiol. 2020 Jun 30;29(3):230-248. doi: 10.5607\/en20017. PMC7344375
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: TUNEL staining, Brain water content, Fluoro-Jade B staining (FJB), Immunofluorescence, RT- PCR, Western blot, modified Garcia score
Citation: Rui Q, Ni H, Gao F, Dang B, Li D, Gao R, Chen G. LRRK2 Contributes to Secondary Brain Injury Through a p38\/Drosha Signaling Pathway After Traumatic Brain Injury in RatsFront Cell Neurosci. 2018 Mar 1;12:51. doi: 10.3389\/fncel.2018.00051. eCollection 2018. PMC5837969
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Immunofluorescence, TUNEL staining, Western blot, spectrophotometer
Citation: Dai W, Wang H, Fang J, Zhu Y, Zhou J, Wang X, Zhou Y, Zhou M. Curcumin provides neuroprotection in model of traumatic brain injury via the Nrf2-ARE signaling pathwayBrain Res Bull. 2018 Jun;140:65-71. doi: 10.1016\/j.brainresbull.2018.03.020. Epub 2018 Apr 4.
TBI Model Type: Weight-drop model
Organism Species: mouse
Assessments: Behavioral, Fluoro-Jade C, Immunofluorescence, Immunohistochemical, Laser scanning confocal microscopy, Long Term Potentiation, NOR, Y maze
Citation: Lecca D, Bader M, Tweedie D, Hoffman AF, Jung YJ, Hsueh SC, Hoffer BJ, Becker RE, Pick CG, Lupica CR, Greig NH.(-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged miceNeurobiol Dis. 2019 Oct;130:104528. doi: 10.1016/j.nbd.2019.104528. Epub 2019 Jul 8.PMC671615210.1016/j.nbd.2019.104528
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Image acquisition, Immunofluorescence, righting reflex, skeleton analysis method
Citation: White MR, VandeVord PJ.Front Cell Neurosci. 2023 Feb 15;17:1076851. doi: 10.3389/fncel.2023.1076851. eCollection 2023.10.3389/fncel.2023.1076851
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Nissl staning, Beam walk test, Bradford method, Immunohistochemistry (IHC), TUNEL staining, EMSA, ELISA, Immunofluorescence
Citation: Zhang D, Hu Y, Sun Q, Zhao J, Cong Z, Liu H, Zhou M, Li K, Hang C.Neuroscience. 2013 May 15;238:209-17. doi: 10.1016/j.neuroscience.2013.02.022. Epub 2013 Feb 24.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ELISA, Immunofluorescence, Lesion volume, Nissl staining, Beam balance test, Brain water content, Prehensile traction test
Citation: Zhao GW, Wang Y, Li YC, Jiang ZL, Sun L, Xi X, He P, Wang GH, Xu SH, Ma DM, Ke KF.J Ethnopharmacol. 2014;151(1):694-703. doi: 10.1016/j.jep.2013.11.041. Epub 2013 Dec 1.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Western blotting, immunofluorescence, length of neurites
Citation: Surgucheva I, He S, Rich MC, Sharma R, Ninkina NN, Stahel PF, Surguchov A.Role of synucleins in traumatic brain injury — an experimental in vitro and in vivo study in mice.Mol Cell Neurosci. 2014 Nov;63:114-23. doi: 10.1016/j.mcn.2014.10.005.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunofluorescence
Citation: Kreipke CW, Morgan RL, Petrov T, Rafols JA.Neurol Res. 2007 Sep;29(6):604-9. doi: 10.1179/016164107X166317.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunofluorescence, Western blot
Citation: Kreipke CW, Morgan R, Roberts G, Bagchi M, Rafols JA.Neurol Res. 2007 Jun;29(4):369-74. doi: 10.1179/016164107X204684.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Rotarod test, modified Neurologic Severity Score (mNSS), Immunofluorescence, Hematoxylin and eosin, Immunohistochemistry (IHC)
Citation: Bonilla C, Zurita M, Otero L, Aguayo C, Vaquero J.Brain Inj. 2009 Aug;23(9):760-9. doi: 10.1080/02699050903133970.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawlay
Assessments: TUNEL staining, transmission electron microscope, Enzyme-linked immunosorbent assay (ELISA), Immunofluorescence, Neurological Severity Score (NSS), Morris Water Maze (MWM), Western blot, Brain water content
Citation: Shen M, Wang S, Wen X, Han XR, Wang YJ, Zhou XM, Zhang MH, Wu DM, Lu J, Zheng YL. Dexmedetomidine exerts neuroprotective effect via the activation of the PI3K\/Akt\/mTOR signaling pathway in rats with traumatic brain injuryBiomed Pharmacother. 2017 Nov;95:885-893. doi: 10.1016\/j.biopha.2017.08.125. Epub 2017 Sep 10.
